公开(公告)号：WO2012154121A1

公开(公告)日：2012-11-15

申请号：PCT/SE2012/050503

申请日：2012-05-11

Applicant: RIESBECK HEALTHCARE SWEDEN AB ,  RIESBECK, Kristian ,  SU, Yu-Ching

Inventor： RIESBECK, Kristian ,  SU, Yu-Ching

IPC: A61K39/102 ,  A61P31/04 ,  C07K14/285

CPC classification number: A61K39/145 ,  A61K39/0208 ,  A61K39/092 ,  A61K39/102 ,  C07K14/285 ,  C12P21/02

Abstract: A vaccine composition comprising a protein, which can be detected in Haemophilus influenzae , having an amino acid sequence as described in SEQ ID NO: 1, or a fragment thereof, is described. The fragment comprises an amino acid sequence having at least 15 contiguous amino acids from the amino acid sequence of SEQ ID NO: 1, and the fragment (if necessary when coupled to a carrier) is capable of raising an immune response which recognises the polypeptide of SEQ ID NO: 1.

Abstract translation: 描述了包含可在流感嗜血杆菌中检测的具有SEQ ID NO：1所示氨基酸序列的蛋白质或其片段的疫苗组合物。 该片段包含具有SEQ ID NO：1的氨基酸序列的至少15个连续氨基酸的氨基酸序列，并且该片段（如果需要，当与载体偶联时）能够提高识别多肽的免疫应答 SEQ ID NO：1。