PHOSPHORYLATED POLYMERS AND CONJUGATES THEREOF
    2.
    发明申请
    PHOSPHORYLATED POLYMERS AND CONJUGATES THEREOF 审中-公开
    磷化聚合物及其结合物

    公开(公告)号:WO0009166A2

    公开(公告)日:2000-02-24

    申请号:PCT/US9918146

    申请日:1999-08-10

    CPC classification number: A61K47/593

    Abstract: The present invention is directed to absorbable polyesters comprising one or more monophosphate functionality; a conjugate comprising the foregoing polyester and a peptide and/or a bioactive agent; microparticles comprising an absorbable polyester; a conjugate comprising the microparticles and a peptide and/or a bioactive agent; an acylated or alkylated polysaccharide having one or more monophosphate functionality; a conjugate comprising the acylated or alkylated polysaccharide and a peptide and/or a bioactive agent; and pharmaceutical compositions thereof.

    Abstract translation: 本发明涉及包含一种或多种单磷酸官能团的可吸收聚酯; 包含上述聚酯和肽和/或生物活性剂的共轭物; 包含可吸收聚酯的微粒; 包含微粒和肽和/或生物活性剂的缀合物; 具有一个或多个单磷酸官能团的酰化或烷基化多糖; 包含酰化或烷基化多糖和肽和/或生物活性剂的缀合物; 及其药物组合物。

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