公开(公告)号：WO2005026460A2

公开(公告)日：2005-03-24

申请号：PCT/US2004/028982

申请日：2004-09-07

申请人： SHAPIRO, Gary ,  MERRY, Scott ,  BAUMAN, Jeffrey

发明人： SHAPIRO, Gary ,  MERRY, Scott ,  BAUMAN, Jeffrey

IPC分类号： E04B

CPC分类号： E04B9/0435 ,  E04B9/0478 ,  E04B9/245 ,  E04F13/12

摘要： A panel, for installation on a ceiling as a component of a matrix grid of similar panels, with the ceiling panels capable of being installed directly on sheetrock ceilings without the otherwise need for affixing a wooden structure to the sheetrock ceiling before affixing the ceiling panels.

摘要翻译： 用于安装在天花板上作为类似面板的矩阵网格的组件的面板，其中天花板面板可以直接安装在平板天花板上，而不需要在贴上天花板面板之前将木结构固定在平板天花板上。

公开(公告)号：WO2023009700A2

公开(公告)日：2023-02-02

申请号：PCT/US2022/038640

申请日：2022-07-28

申请人： TAKEDA PHARMACEUTICAL COMPANY LIMITED ,  SHAPIRO, Gary

发明人： TAKE, Chihiro ,  KASSAI, Yoshiaki ,  HE, Xingyue ,  KUHN, Chantal

IPC分类号： C07K16/28 ,  C07K16/30 ,  C12N15/86 ,  A61K2039/5156 ,  A61K39/0011 ,  A61P35/00 ,  C07K14/523 ,  C07K14/5443 ,  C07K14/7051 ,  C07K2317/622 ,  C07K2319/03

摘要： Disclosed herein are engineered immune cells that specifically recognizes mesothelin and expresses IL-15 and optionally CCL19. Also disclosed herein are isolated nucleic acid molecules comprising a polynucleotide encoding a chimeric antigen receptor (CAR) comprising an antibody that specifically recognizes mesothelin, and a 4- IBB intracellular region; and a polynucleotide encoding IL- 15; and optionally a polynucleotide encoding CCL19, vectors, pharmaceutical compositions comprising the nucleic acid molecules, and methods of using the engineered immune cells.

公开(公告)号：WO2005026460A3

公开(公告)日：2007-02-15

申请号：PCT/US2004028982

申请日：2004-09-07

申请人： SHAPIRO GARY ,  MERRY SCOTT ,  BAUMAN JEFFREY

发明人： SHAPIRO GARY ,  MERRY SCOTT ,  BAUMAN JEFFREY

IPC分类号： E04D1/36 ,  E04B9/04 ,  E04B9/24 ,  E04F13/12

CPC分类号： E04B9/0435 ,  E04B9/0478 ,  E04B9/245 ,  E04F13/12

摘要： A panel, for installation on a ceiling as a component of a matrix grid of similar panels, with the ceiling panels capable of being installed directly on sheetrock ceilings without the otherwise need for affixing a wooden structure to the sheetrock ceiling before affixing the ceiling panels.

摘要翻译： 一个面板，用于安装在天花板上作为类似面板的矩阵网格的组件，天花板面板可以直接安装在平板天花板上，而不需要在贴上天花板板之前将木结构固定在平板天花板上。