公开(公告)号：WO2009097077A3

公开(公告)日：2009-08-06

申请号：PCT/US2009/000129

申请日：2009-01-07

申请人： CODA THERAPEUTICS, INC. ,  MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

发明人： MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

IPC分类号： C12N15/11 ,  A61K48/00

摘要： Methods and compositions comprising an anti-ostepontin agent and/or a PDGF receptor blocker or antagonist, alone or in combination with one or more anti-connexin agents, for example, one or more anti-connexin polynucleotides and/or one or more anti-connexin peptides or peptidomimetics, are provided for the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.

公开(公告)号：WO2009097077A9

公开(公告)日：2009-08-06

申请号：PCT/US2009/000129

申请日：2009-01-07

申请人： CODA THERAPEUTICS, INC. ,  MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

发明人： MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

IPC分类号： C12N15/11 ,  A61K48/00

摘要： Methods and compositions comprising an anti-ostepontin agent and/or a PDGF receptor blocker or antagonist, alone or in combination with one or more anti-connexin agents, for example, one or more anti-connexin polynucleotides and/or one or more anti-connexin peptides or peptidomimetics, are provided for the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.

公开(公告)号：WO2009097077A2

公开(公告)日：2009-08-06

申请号：PCT/US2009/000129

申请日：2009-01-07

申请人： CODA THERAPEUTICS, INC. ,  MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

发明人： MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

IPC分类号： C12N15/11 ,  A61K48/00

CPC分类号： C12N15/1136 ,  C12N2310/11 ,  C12N2310/14

摘要： Methods and compositions comprising an anti-ostepontin agent and/or a PDGF receptor blocker or antagonist, alone or in combination with one or more anti-connexin agents, for example, one or more anti-connexin polynucleotides and/or one or more anti-connexin peptides or peptidomimetics, are provided for the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.

摘要翻译： 包含单独或与一种或多种抗连接蛋白试剂，例如一种或多种抗连接蛋白多核苷酸和/或一种或多种抗连接蛋白多核苷酸组合的抗 - 奥替替药物和/或PDGF受体阻断剂或拮抗剂的方法和组合物， 连接蛋白肽或肽模拟物用于促进和/或改善伤口愈合和/或组织修复，以及用于抗瘢痕形成，抗炎，抗纤维化和抗粘连的适应症。