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    WOUND HEALING COMPOSITIONS AND TREATMENTS
    2.
    发明申请
    WOUND HEALING COMPOSITIONS AND TREATMENTS 审中-公开
    创伤治疗组合物和治疗

    公开(公告)号：WO2009097077A2

    公开(公告)日：2009-08-06

    申请号：PCT/US2009/000129

    申请日：2009-01-07

    申请人： CODA THERAPEUTICS, INC. ,  MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

    发明人： MORI, Ryoichi ,  MARTIN, Paul ,  DUFT, Bradford, J. ,  SHAW, Tanya

    IPC分类号： C12N15/11 ,  A61K48/00

    CPC分类号： C12N15/1136 ,  C12N2310/11 ,  C12N2310/14

    摘要： Methods and compositions comprising an anti-ostepontin agent and/or a PDGF receptor blocker or antagonist, alone or in combination with one or more anti-connexin agents, for example, one or more anti-connexin polynucleotides and/or one or more anti-connexin peptides or peptidomimetics, are provided for the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications.

    摘要翻译： 包含单独或与一种或多种抗连接蛋白试剂，例如一种或多种抗连接蛋白多核苷酸和/或一种或多种抗连接蛋白多核苷酸组合的抗 - 奥替替药物和/或PDGF受体阻断剂或拮抗剂的方法和组合物， 连接蛋白肽或肽模拟物用于促进和/或改善伤口愈合和/或组织修复，以及用于抗瘢痕形成，抗炎，抗纤维化和抗粘连的适应症。

    IMPAIRED WOUND HEALING COMPOSITIONS AND TREATMENTS
    6.
    发明申请
    IMPAIRED WOUND HEALING COMPOSITIONS AND TREATMENTS 审中-公开
    伤口愈合组合物和治疗

    公开(公告)号：WO2009075882A2

    公开(公告)日：2009-06-18

    申请号：PCT/US2008/013656

    申请日：2008-12-11

    申请人： CoDa Therapeutics, Inc. ,  DUFT, Bradford, J.

    发明人： DUFT, Bradford, J.

    IPC分类号： A61K48/00

    CPC分类号： C12N15/1138 ,  A61K38/10 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2320/31 ,  A61K2300/00

    摘要： Methods and compositions comprising combinations and uses of a first anti-connexin agent and a second anti-connexin agent, for example, one or more anti-connexin polynucleotides and one or more anti-connexin peptides or peptidomimetics, are provided for therapeutic use including uses for the promotion and/or improvement of wounds and wound healing and/or tissue repair.

    摘要翻译： 包含第一抗连接蛋白剂和第二抗连接蛋白剂的组合和用途的方法和组合物，例如一种或多种抗连接蛋白多核苷酸和一种或多种抗连接蛋白肽或肽模拟物 提供用于治疗用途，包括用于促进和/或改善伤口和伤口愈合和/或组织修复。

    IMPAIRED WOUND HEALING COMPOSITIONS AND TREATMENTS
    7.
    发明申请
    IMPAIRED WOUND HEALING COMPOSITIONS AND TREATMENTS 审中-公开
    受伤的治疗组合物和治疗

    公开(公告)号：WO2009075881A2

    公开(公告)日：2009-06-18

    申请号：PCT/US2008013655

    申请日：2008-12-11

    申请人： CODA THERAPEUTICS INC ,  BECKER DAVID L ,  GREEN COLIN R ,  DUFT BRADFORD J

    发明人： BECKER DAVID L ,  GREEN COLIN R ,  DUFT BRADFORD J

    IPC分类号： C07K16/18 ,  A61K38/02 ,  C07K2/00

    CPC分类号： C07K14/78

    摘要： Methods, compounds, compositions, kits and articles of manufacture comprising one or more gap junction modulating agents for treatment of wounds that do not heal at expected rates, including chronic wounds, delayed healing wounds, incompletely healing wounds, and dehiscent wounds in a subject in need thereof.

    摘要翻译： 方法，化合物，组合物，试剂盒和制品，其包含一种或多种间隙连接调节剂，用于治疗以预期速率不愈合的伤口，包括慢性伤口，延迟愈合伤口，不完全愈合的伤口和受试者的开裂伤口 需要。

    TREATMENT OF PAIN WITH GAP JUNCTION MODULATION COMPOUNDS
    10.
    发明申请
    TREATMENT OF PAIN WITH GAP JUNCTION MODULATION COMPOUNDS 审中-公开
    用缝隙调节化合物治疗疼痛

    公开(公告)号：WO2009148613A1

    公开(公告)日：2009-12-10

    申请号：PCT/US2009/003408

    申请日：2009-06-04

    申请人： CODA THERAPEUTICS, INC. ,  DUFT, Bradford, J. ,  GREEN, Colin

    发明人： DUFT, Bradford, J. ,  GREEN, Colin

    IPC分类号： C12N15/11 ,  A61P25/00

    CPC分类号： C12N15/1138 ,  C07K14/705 ,  C12N2310/11 ,  C12N2310/14

    摘要： The present invention relates to delivery, including transdermal delivery, of a therapeutically effective amount of a compound useful for modulating gap junction formation and function, including an oligonucleotide for reducing gap junction formation and function, and methods and compositions for treating a subject suffering from pain associated with a disease, disorder or condition and associated with pain, including but not limited to muscle pain, ligament pain, tendon pain, joint pain and post-operative pain.

    摘要翻译： 本发明涉及治疗有效量的用于调节间隙连接形成和功能的化合物的递送（包括透皮递送），包括用于减少间隙连接形成和功能的寡核苷酸，以及用于治疗患有疼痛的受试者的方法和组合物 与疾病，病症或病症相关并且与疼痛相关，包括但不限于肌肉疼痛，韧带疼痛，肌腱疼痛，关节疼痛和手术后疼痛。