Abstract:
The present invention relates to a composition for preventing and treating obesity containing highly water-soluble ß-cyclodextrin derivatives as an active ingredient. More specifically, the composition containing highly water-soluble ß-cyclodextrin derivatives, particularly 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD, HPBCD), inhibits the weight increase induced by a high fat diet, inhibits appetite through the decrease of food intake, reduces body fat, reduces the weight of a liver, and remarkably inhibits the rapid increase of blood glucose induced by the intake of glucose and maltose on an empty stomach, thereby enabling helpful use for preventing and treating obesity, preventing and treating various diseases induced by obesity and inhibiting the rapid increase of blood sugar after meals.
Abstract:
The present invention relates to a composition for preventing and treating obesity containing highly water-soluble ß-cyclodextrin derivatives as an active ingredient. More specifically, the composition containing highly water-soluble ß-cyclodextrin derivatives, particularly 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD, HPBCD), inhibits the weight increase induced by a high fat diet, inhibits appetite through the decrease of food intake, reduces body fat, reduces the weight of a liver, and remarkably inhibits the rapid increase of blood glucose induced by the intake of glucose and maltose on an empty stomach, thereby enabling helpful use for preventing and treating obesity, preventing and treating various diseases induced by obesity and inhibiting the rapid increase of blood sugar after meals.