公开(公告)号：WO2013026474A1

公开(公告)日：2013-02-28

申请号：PCT/EP2011/064461

申请日：2011-08-23

Applicant: ETHICON ENDO-SURGERY, INC. ,  MURRAY, Michael A. ,  ZEINER, Mark S. ,  BILOTTI, Federico ,  D'ARCANGELO, Michele ,  ORTIZ, Mark Steven ,  HARRIS, Jason ,  PASTORELLI, Alessandro ,  VOEGELE, James W. ,  STOKES, Michael J.

Inventor： MURRAY, Michael A. ,  ZEINER, Mark S. ,  BILOTTI, Federico ,  D'ARCANGELO, Michele ,  ORTIZ, Mark Steven ,  HARRIS, Jason ,  PASTORELLI, Alessandro ,  VOEGELE, James W. ,  STOKES, Michael J.

IPC: A61F5/00

CPC classification number: A61F5/0076 ,  A61F5/003

Abstract: An endoluminal sleeve device (1) for internally lining a section of the GI tract comprises a sleeve (2) configured for deployment inside a GI tract, an anchoring structure (8) with a support ring (9) connected to a proximal sleeve end (4), a plurality of expandable arms (11) hinged to the support ring (9) and movable from a "closed umbrella" configuration to an "open umbrella" configuration,a membrane (15) connected to the arms (11) and extending all around the anchoring structure (8) thereby forming a webbing between adjacent arms (11) and means for locking the arms (11) in the "open umbrella" configuration.

Abstract translation: 用于内部衬里胃肠道部分的腔内套管装置（1）包括构造成用于部署在胃肠道内的套管（2），具有连接到近端套管端部（9）的支撑环（9）的锚定结构（8） 多个可伸缩臂（11），其铰接到支撑环（9）并且可以从“闭合伞”构型移动到“开放式伞”构型，膜（15）连接到臂（11）并延伸 在所述锚定结构（8）周围的所有周围，由此在相邻臂（11）之间形成织带，以及用于将所述臂（11）锁定在所述“开放伞”构造中的装置。

公开(公告)号：WO2013026473A1

公开(公告)日：2013-02-28

申请号：PCT/EP2011/064460

申请日：2011-08-23

Applicant: ETHICON ENDO-SURGERY, INC. ,  VOEGELE, James, W. ,  ORTIZ, Mark, Steven ,  ZEINER, Mark, S. ,  HARRIS, Jason ,  D'ARCANGELO, Michele ,  BILOTTI, Federico

Inventor： VOEGELE, James, W. ,  ORTIZ, Mark, Steven ,  ZEINER, Mark, S. ,  HARRIS, Jason ,  D'ARCANGELO, Michele ,  BILOTTI, Federico

IPC: A61F5/00

CPC classification number: A61F5/0079 ,  A61F5/0076

Abstract: An endoluminal sleeve device (1) for internally lining a section of the GI tract comprises a sleeve (2) configured for deployment inside a duodenum, the sleeve (2) having walls of a flexible material defining a sleeve lumen (3), a proximal end (4) defining a proximal lumen opening (5), and a distal end (6) defining a distal lumen opening (7), the proximal sleeve end (4) forming an anchoring component (8) extending along a circumference of the sleeve, the anchoring component (8) having a collapsed slender transport configuration and a bulky annular deployed configuration having a size that cannot fit through a human pylorus, and a plurality of auxiliary fixation tabs (9) extending from the anchoring component (8).

Abstract translation: 用于内部衬里胃肠道部分的内腔套管装置（1）包括构造成用于展开在十二指肠内部的套筒（2），所述套管（2）具有限定套筒内腔（3）的柔性材料的壁， 限定近侧管腔开口（5）的端部（4）和限定远端腔开口（7）的远端（6），所述近侧套筒端部（4）形成沿所述套筒的圆周延伸的锚定部件 具有塌缩的细长运输构造的锚固部件（8）和具有不能穿过人类幽门的尺寸的庞大的环形部署构型以及从锚定部件（8）延伸的多个辅助固定突片（9）。

公开(公告)号：WO2012102902A1

公开(公告)日：2012-08-02

申请号：PCT/US2012/021532

申请日：2012-01-17

Applicant: ETHICON ENDO-SURGERY, INC. ,  VOEGELE, James, W. ,  VOEGELE, Aaron, C.

Inventor： VOEGELE, James, W. ,  VOEGELE, Aaron, C.

IPC: A61B17/00 ,  A61B17/072 ,  A61B17/115 ,  A61B17/34

CPC classification number: A61B17/07207 ,  A61B17/1152 ,  A61B17/34 ,  A61B2017/003 ,  A61B2017/00539 ,  A61B2017/00862

Abstract: Mechanisnns for altering the shape of a cell or chamber of a shaft or an actuation drive of an instrument are provided. The mechanisms may selectively rigidize the shaft of surgical or diagnostic instruments. The shaft assembly includes a shaft operatively connectable to a control member, at least one cell or a set of cells defined within the shaft, a shape altering material contained within the cell or cells, and, an activation link operatively connectable to a source of activation energy for delivering activation energy to each cell for activating the shape altering material to selectively rigidize or unrigidize the shaft. An actuator for producing work is also provided that includes an element within a housing that defines a cell or a set of cells. The shape altering material is contained within the cells, and a source of activation energy operatively connected to each cell for activating the shape altering material to expand or contract the cell. The element is operatively connectable to a driving member of an instrument such that the change in the cell is translated to the driving member to facilitate the production of work.

Abstract translation: 提供了用于改变轴的电池或室的形状或仪器的致动驱动器的机构。 这些机构可以选择性地将外科手术或诊断仪器的轴刚性化。 轴组件包括可操作地连接到控制构件的轴，在轴内限定的至少一个单元或一组单元，容纳在单元或单元内的形状改变材料，以及可操作地连接到激活源的激活连接 用于将活化能递送到每个电池用于激活形状改变材料以选择性地使轴固定或脱离刚度的能量。 还提供了一种用于生产作业的致动器，其包括限定一个单元或一组单元的壳体内的元件。 形状改变材料包含在细胞内，活化能源可操作地连接到每个细胞，用于激活形状改变材料以扩展或收缩细胞。 元件可操作地连接到仪器的驱动构件，使得电池的变化被转换为驱动构件以便于工作的产生。

公开(公告)号：WO2012007052A1

公开(公告)日：2012-01-19

申请号：PCT/EP2010/060291

申请日：2010-07-16

Applicant: ETHICON ENDO-SURGERY, INC. ,  GALVAO NETO, Manoel ,  ZEINER, Mark, S. ,  VOEGELE, James, W. ,  ALBRECHT, Thomas Edward ,  PASTORELLI, Alessandro ,  ORTIZ, Mark Steven ,  D'ARCANGELO, Michele

Inventor： GALVAO NETO, Manoel ,  ZEINER, Mark, S. ,  VOEGELE, James, W. ,  ALBRECHT, Thomas Edward ,  PASTORELLI, Alessandro ,  ORTIZ, Mark Steven ,  D'ARCANGELO, Michele

IPC: A61B17/11

CPC classification number: A61B17/11 ,  A61B17/1114 ,  A61B2017/00867 ,  A61B2017/00876 ,  A61B2017/1139

Abstract: A method for diverting biliary fluid from a biliary fluid flow path to a target location in the intestine distal to a duodenal papilla of Vater, the method comprising the steps of visualization of a gallbladder (8) and of a portion of the intestinal tract (2, 3, 4, 5), accessing endoluminally the portion of the intestinal tract (2, 3, 4, 5), extending a guide (11) from the portion of the intestinal tract through a gallbladder wall and through an intestinal wall at a target portion (12) of the intestine significantly distal to the papilla of Vater (10), approximating the gallbladder (8) and the target portion (12) of intestine to each other along the guide (11) and anastomosing the gallbladder (8) to the target portion (12) of intestine to create a cholecysto-enterostomy (13).

Abstract translation: 一种用于将胆汁液从胆汁流动路径转移到Vater十二指肠乳头远端的肠中的目标位置的方法，所述方法包括以下步骤：胆囊（8）和肠道的一部分（2） ，3,4,5），在阴道内接近肠道部分（2,3,4,5），将导管（11）从肠道部分延伸穿过胆囊壁并通过肠壁 大肠远端的Vater（10）的乳头的肠的目标部分（12），沿着引导件（11）将胆囊（8）和肠的目标部分（12）彼此近似并且吻合胆囊（8） 到肠的目标部分（12）以产生胆囊肠造口术（13）。

公开(公告)号：WO2011149893A2

公开(公告)日：2011-12-01

申请号：PCT/US2011/037678

申请日：2011-05-24

Applicant: ETHICON ENDO-SURGERY, INC. ,  ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  HUITEMA, Thomas, W. ,  HUNT, John, V. ,  MALAVIYA, Prasanna ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  STULEN, Foster, B. ,  VOEGELE, James, W. ,  WEISENBURGH, William, B., II ,  WIDENHOUSE, Christopher, W. ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

Inventor： ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  HUITEMA, Thomas, W. ,  HUNT, John, V. ,  MALAVIYA, Prasanna ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  STULEN, Foster, B. ,  VOEGELE, James, W. ,  WEISENBURGH, William, B., II ,  WIDENHOUSE, Christopher, W. ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

IPC: A61F2/04

CPC classification number: A61F5/0076 ,  A61F2/04 ,  A61F5/0013 ,  A61F5/0026 ,  A61F5/0079 ,  A61F2002/045

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.

Abstract translation: 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施例中，可植入系统包括将治疗物质递送到患者的胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。

公开(公告)号：WO2011149877A2

公开(公告)日：2011-12-01

申请号：PCT/US2011/037658

申请日：2011-05-24

Applicant: ETHICON ENDO-SURGERY, INC. ,  ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F., Jr. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  MALAVIYA, Prasanna ,  MARSH, Glenda, C. ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  VOEGELE, James, W. ,  WEANER, Lauren, S. ,  WEISENBURGH, William, B. ,  WIDENHOUSE, Christopher, W. ,  WIDENHOUSE, Tamara, S., Vetro ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

Inventor： ALBRECHT, Thomas, E. ,  ALDRIDGE, Jeffrey, L. ,  CONLON, Sean, P. ,  CROPPER, Michael, S. ,  HERRERA-DAVIS, Denzel, Z. ,  DLUGOS, Daniel, F., Jr. ,  HARRIS, Jason, L. ,  HESS, Christopher, J. ,  MALAVIYA, Prasanna ,  MARSH, Glenda, C. ,  ORTIZ, Mark, S. ,  OVERMYER, Mark, D. ,  PASTORELLI, Alessandro ,  ROBERTSON, Galen, C. ,  SHELTON, Frederick, E. ,  STOKES, Michael, J. ,  VOEGELE, James, W. ,  WEANER, Lauren, S. ,  WEISENBURGH, William, B. ,  WIDENHOUSE, Christopher, W. ,  WIDENHOUSE, Tamara, S., Vetro ,  WOODARD, James, A., Jr. ,  YATES, David, C. ,  ZEINER, Mark, S. ,  ZWOLINSKI, Andrew, M.

IPC: A61M37/00 ,  A61M5/168 ,  A61N1/36 ,  A61M5/00 ,  A61F2/00 ,  A61K31/20

CPC classification number: A61M31/002 ,  A61F2/04 ,  A61F5/0013 ,  A61F5/0026 ,  A61F2002/045 ,  A61K9/0065 ,  A61M5/14276 ,  A61M39/0208 ,  A61M2210/106 ,  A61M2210/1064 ,  A61N1/0509 ,  A61N1/36007 ,  A61N1/37205

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.

Abstract translation: 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。 植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质 从植入物到胃肠道。

公开(公告)号：WO2010132558A2

公开(公告)日：2010-11-18

申请号：PCT/US2010/034534

申请日：2010-05-12

Applicant: ETHICON ENDO-SURGERY, INC. ,  HESS, Christopher, J. ,  VOEGELE, James, W. ,  MYERS, Stephan, Ray

Inventor： HESS, Christopher, J. ,  VOEGELE, James, W. ,  MYERS, Stephan, Ray

IPC: A61B17/02

CPC classification number: A61B17/0218 ,  A61B2017/00004 ,  A61B2017/0212

Abstract: A retractor instrument for use in surgery having a body section and attachment tabs for securing the retractor to tissue. The retractor may have multiple body sections joined by hinges or ribs and may be rigid or flexible or some combination thereof. The retractor may comprise bioabsorbable material as well as hemostatic material. The retractor is suitable for use with clips, staples, sutures and tacks.

Abstract translation: 一种用于手术中的收缩器器具，具有主体部分和用于将牵开器固定到组织的附接突片。 牵开器可以具有通过铰链或肋连接的多个主体部分，并且可以是刚性的或柔性的或其某种组合。 牵开器可包括生物可吸收材料以及止血材料。 卷收器适用于夹子，缝钉，缝线和钉。

公开(公告)号：WO2008137531A9

公开(公告)日：2008-11-13

申请号：PCT/US2008/062195

申请日：2008-05-01

Applicant: ETHICON-ENDO-SURGERY, INC ,  BAKOS, Gregory, J. ,  CUNNINGHAM, Christie, M. ,  STEFANCHIK, David ,  VOEGELE, James, W. ,  STOKES, Michael, J. ,  HESS, Christopher, J. ,  SPIVEY, James, T. ,  LONG, Gary, L. ,  BALLY, Kurt, R. ,  GHABRIAL, Ragae, M. ,  NOBIS, Rudolph, H.

Inventor： BAKOS, Gregory, J. ,  CUNNINGHAM, Christie, M. ,  STEFANCHIK, David ,  VOEGELE, James, W. ,  STOKES, Michael, J. ,  HESS, Christopher, J. ,  SPIVEY, James, T. ,  LONG, Gary, L. ,  BALLY, Kurt, R. ,  GHABRIAL, Ragae, M. ,  NOBIS, Rudolph, H.

IPC: A61B1/01 ,  A61B17/00 ,  A61M25/04

公开(公告)号：WO2008118684A1

公开(公告)日：2008-10-02

申请号：PCT/US2008/057323

申请日：2008-03-18

Applicant: ETHICON ENDO-SURGERY, INC. ,  VOEGELE, James, W.

Inventor： VOEGELE, James, W.

IPC: A61B5/05

CPC classification number: A61B5/06 ,  A61B5/064 ,  A61B6/12 ,  G06T7/73 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/30004 ,  G06T2207/30244

Abstract: A storage medium contains a program which instructs a computer to recognize a predetermined shape of each of at least one portion of a medical assembly as a real-world fiducial in image data of a patient when the image data includes the predetermined shape and is received by the digital computer. The at-least-one portion has another function apart from functioning as a real-world fiducial. A medical apparatus includes a medical assembly and a storage medium. The medical assembly includes a component having at-least-one portion each with a predetermined shape. The storage medium contains a program which instructs a computer to recognize the predetermined shape of each of the at-least-one portion as a real-world fiducial in image data of a patient when the image data includes the predetermined shape and is received by the digital computer. The component has another function apart from functioning as a real-world fiducial.

Abstract translation: 存储介质包含程序，其指示计算机当图像数据包括预定形状并且被图像数据接收时，将医疗组件的至少一部分中的每一者的预定形状识别为患者的图像数据中的真实世界基准 数字电脑。 至少一个部分除了作为现实世界的基准之外还有另一个功能。 医疗装置包括医疗组件和存储介质。 医疗组件包括具有至少一部分的具有预定形状的部件。 存储介质包含程序，该程序指示计算机当图像数据包括预定形状并且被图像数据接收时，将至少一部分中的每一个的预定形状识别为患者的图像数据中的真实世界基准 数码电脑 除了作为现实世界的基准之外，该组件还具有另外的功能。

公开(公告)号：WO2008082955A2

公开(公告)日：2008-07-10

申请号：PCT/US2007/087933

申请日：2007-12-18

Applicant: ETHICON ENDO-SURGERY, INC ,  WEISENBURGH, II, William Bruce ,  CROPPER, Michael S. ,  GILL, Robert P. ,  MARTIN, David T. ,  HESS, Christopher J. ,  VOEGELE, James W.

Inventor： WEISENBURGH, II, William Bruce ,  CROPPER, Michael S. ,  GILL, Robert P. ,  MARTIN, David T. ,  HESS, Christopher J. ,  VOEGELE, James W.

IPC: A61B17/04 ,  A61B17/064 ,  A61B17/06 ,  A61B17/00

CPC classification number: A61B17/0401 ,  A61B17/06004 ,  A61B2017/00004 ,  A61B2017/00526 ,  A61B2017/0403 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0417 ,  A61B2017/0458 ,  A61B2017/06052 ,  A61B2017/06057

Abstract: A first extruded member in joined to a molded member to form an integrated component. In one exemplary form, a surgical anchor is overmolded onto the end of an extruded suture to form a suture/anchor system.

Abstract translation: 第一挤压构件，其连接到模制构件以形成集成部件。 在一个示例性形式中，手术锚固件被包覆模制到挤压缝合线的端部上以形成缝线/锚定系统。