公开(公告)号：WO8703287A3

公开(公告)日：1987-08-13

申请号：PCT/CH8600157

申请日：1986-11-13

Applicant: GIVAUDAN & CIE SA ,  WILD HANS JAKOB

Inventor： WILD HANS-JAKOB

IPC: C07C69/738 ,  A61K8/35 ,  A61Q13/00 ,  C07C45/00 ,  C07C45/48 ,  C07C45/64 ,  C07C45/66 ,  C07C45/67 ,  C07C49/707 ,  C07C49/753 ,  C07C67/00 ,  C07C67/343 ,  C11B9/00

CPC classification number: C11B9/003 ,  C07C45/64 ,  C07C45/66 ,  C07C45/673 ,  C07C45/676 ,  C07C49/707 ,  C07C49/753 ,  C07C49/687

Abstract: New process for the preparation of compounds of formula (I) in which R1 represents alkyl C1-5, in particular methyl, ethyl, propyl isopropyl, and the two radicals R2 represent independently of one another hydrogen or alkyl C1-5, in particular hydrogen or methyl, ethyl, propyl or isopropyl. The process is characterized by the hydrolysis of a compound of formula (II) in which R is alkoxy C1-4, chlorine, bromine or alcanoyloxy C1-4, R1 and R2 have the above meaning and R3 is alkyl C1-4, and by the fact that the compound obtained is subjected to aldol condensation and, in the case where R = alkoxy C1-4, the reaction compound is again subjected to acid treatment. The compounds of formula (I) are mainly aromatics.

公开(公告)号：WO1987003287A2

公开(公告)日：1987-06-04

申请号：PCT/CH1986000157

申请日：1986-11-13

Applicant: L. GIVAUDAN & CIE SOCIETE ANONYME ,  WILD, Hans-Jakob

Inventor： L. GIVAUDAN & CIE SOCIETE ANONYME

IPC: C07K45/66

CPC classification number: C11B9/003 ,  C07C45/64 ,  C07C45/66 ,  C07C45/673 ,  C07C45/676 ,  C07C49/707 ,  C07C49/753 ,  C07C49/687

Abstract: New process for the preparation of compounds of formula (I) in which R represents alkyl C1-5, in particular methyl, ethyl, propyl isopropyl, and the two radicals R represent independently of one another hydrogen or alkyl C1-5, in particular hydrogen or methyl, ethyl, propyl or isopropyl. The process is characterized by the hydrolysis of a compound of formula (II) in which R is alkoxy C1-4, chlorine, bromine or alcanoyloxy C1-4, R and R have the above meaning and R is alkyl C1-4, and by the fact that the compound obtained is subjected to aldol condensation and, in the case where R = alkoxy C1-4, the reaction compound is again subjected to acid treatment. The compounds of formula (I) are mainly aromatics.

Abstract translation: 制备式（I）化合物的新方法，其中R 1表示烷基C1-5，特别是甲基，乙基，丙基异丙基和两个基团R 2彼此独立地表示氢或烷基C1 -5，特别是氢或甲基，乙基，丙基或异丙​​基。 该方法的特征在于其中R是烷氧基C 1-4，氯，溴或烷酰氧基C 1-4的式（II）化合物的水解，R 1和R 2具有上述含义，R 3 >为烷基C1-4，并且由所得化合物经醛醇缩合，而在R =烷氧基C 1-4的情况下，反应化合物再次进行酸处理。 式（I）化合物主要是芳族化合物。