公开(公告)号：WO2008151460A3

公开(公告)日：2010-04-01

申请号：PCT/CH2008000266

申请日：2008-06-11

Applicant: GIVAUDAN SA ,  FURRER STEFAN MICHAEL ,  YEP GREGORY L ,  FLAMME ERIC

Inventor： FURRER STEFAN MICHAEL ,  YEP GREGORY L ,  FLAMME ERIC

IPC: A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61Q11/00 ,  C07C69/38 ,  C07C69/40 ,  C07C229/12

CPC classification number: A61Q11/00 ,  A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/244 ,  C07C69/38 ,  C07C69/40 ,  C07C229/12 ,  C07C2602/42

Abstract: A cooling composition comprising at least one compound of the Formula (I) in which R is selected from the group of moieties consisting of (CH2)nCOOR''; (CH2)nCONMe2; (CH2)nOR''; and CHNH2CH3; where n is 1 - 3 and R'' is independently selected from hydrogen, methyl and ethyl; and R' is selected from the group consisting of the moieties fenchyl, D-bornyl, L-bornyl, exo-norbornyl, 2-methylisobornyl, 2-ethylfenchyl, 2-methylbornyl, cis-pinan-2-yl, verbanyl and isobornyl. The compositions are useful in providing cooling sensations to the skin or mucous membranes of the body.

Abstract translation: 一种冷却组合物，其包含至少一种式（I）化合物，其中R选自由（CH 2）n COOR“组成的部分; （CH 2）nCONMe2; （CH 2）NOR ''; 和CHNH 2 CH 3; 其中n为1-3，R“独立地选自氢，甲基和乙基; 并且R'选自萜烯基，D-冰片基，L-冰片基，外降冰片基，2-甲基异山梨醇基，2-乙基枞基，2-甲基戊酰基，顺式 - 蒎烷-2-基，缬氨酰基和异冰片基。 该组合物可用于向身体的皮肤或粘膜提供冷却感。

公开(公告)号：WO2008151460A2

公开(公告)日：2008-12-18

申请号：PCT/CH2008/000266

申请日：2008-06-11

Applicant: GIVAUDAN SA ,  FURRER, Stefan, Michael ,  YEP, Gregory, L. ,  FLAMME, Eric

Inventor： FURRER, Stefan, Michael ,  YEP, Gregory, L. ,  FLAMME, Eric

IPC: A61K8/33 ,  A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61Q19/00

CPC classification number: A61Q11/00 ,  A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/244 ,  C07C69/38 ,  C07C69/40 ,  C07C229/12 ,  C07C2602/42

Abstract: A cooling composition comprising at least one compound of the Formula (I) in which R is selected from the group of moieties consisting of (CH 2 ) n COOR''; (CH 2 ) n CONM e2 ; (CH 2 ) n OR''; and CHNH 2 CH 3 ; where n is 1 - 3 and R'' is independently selected from hydrogen, methyl and ethyl; and R' is selected from the group consisting of the moieties fenchyl, D-bornyl, L-bornyl, exo-norbornyl, 2-methylisobornyl, 2-ethylfenchyl, 2-methylbornyl, cis-pinan-2-yl, verbanyl and isobornyl. The compositions are useful in providing cooling sensations to the skin or mucous membranes of the body.

Abstract translation: 一种冷却组合物，其包含至少一种式（I）化合物，其中R选自由（CH 2）n COOR“组成的部分; （CH 2）nCONMe2; （CH 2）NOR ''; 和CHNH 2 CH 3; 其中n为1-3，R“独立地选自氢，甲基和乙基; 并且R'选自萜烯基，D-冰片基，L-冰片基，外降冰片基，2-甲基异山梨醇基，2-乙基枞基，2-甲基戊酰基，顺式 - 蒎烷-2-基，甲醯基和异冰片基。 该组合物可用于向身体的皮肤或粘膜提供冷却感。

公开(公告)号：WO2008148234A1

公开(公告)日：2008-12-11

申请号：PCT/CH2008/000247

申请日：2008-06-05

Applicant: GIVAUDAN SA ,  GRAY, Kimberley ,  YEP, Gregory, L. ,  EILERMAN, Robert, G.

Inventor： GRAY, Kimberley ,  YEP, Gregory, L. ,  EILERMAN, Robert, G.

IPC: A23L1/22

CPC classification number: A23L27/88

Abstract: A method of enhancing the perceived saltiness of an orally-ingestible composition, comprising the incorporation therein of a compound which is a cooling compound in a proportion that is below the cooling threshold but that provides a salt enhancement. Therefore, less salt is needed to provide a desirable salty taste to foodstuffs, beverages and the like, and the products are healthier as a result.

Abstract translation: 一种增强口感可食用组合物的感觉咸味的方法，其包括以低于冷却阈值但提供盐增强的比例掺入作为冷却化合物的化合物。 因此，为了对食品，饮料等提供理想的咸味，需要较少的盐，结果，产品更健康。