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    POLYMERIC EMULSIFIER AND LUBRICITY ADDITIVES FOR AQUEOUS METAL REMOVAL FORMING ROLLING, OR OTHER APPLICATIONS
    3.
    发明申请
    POLYMERIC EMULSIFIER AND LUBRICITY ADDITIVES FOR AQUEOUS METAL REMOVAL FORMING ROLLING, OR OTHER APPLICATIONS 审中-公开
    聚合物乳化剂和润滑添加剂用于水性金属去除成型轧制或其它应用

    公开(公告)号：WO2017117346A1

    公开(公告)日：2017-07-06

    申请号：PCT/US2016/069107

    申请日：2016-12-29

    Applicant: AFTON CHEMICAL CORPORATION

    Inventor： ROSS, Matthew, Paul ,  WILLIAMS, Carl ,  ANDERSON, Steven ,  JARVIS, Anthony, Nicholas

    IPC: C07C69/40 ,  C07C69/704 ,  C07C59/265 ,  C07C55/10 ,  C08F2/22 ,  C08K5/10 ,  C10M145/06 ,  C10M145/16

    CPC classification number: B01F17/0028 ,  C10M145/22 ,  C10M173/00 ,  C10M2201/062 ,  C10M2201/087 ,  C10M2203/1065 ,  C10M2207/18 ,  C10M2209/102 ,  C10M2215/042 ,  C10N2220/021 ,  C10N2220/03 ,  C10N2230/18 ,  C10N2230/24 ,  C10N2230/52 ,  C10N2240/401 ,  C10N2240/402 ,  C10N2240/406 ,  C10N2250/02 ,  C10N2250/021 ,  C10N2210/02

    Abstract: The present invention generally relates to fluids for metalworking and other applications and, in particular, to compounds useful in such fluids. For instance, some aspects of the invention are generally directed to molecular compounds comprising polydentate acids (and derivatives thereof), polyalkylene glycols, and anhydrides (e.g., alkyl and/or alkenyl succinic anhydrides, and/or derivatives thereof), which may be reacted together, e.g., covalently, to form a compound useful for such fluids. An example of a polydentate acid is trimellitic acid; an example of a polyalkylene glycol is polyethylene glycol; an example of an anhydride is poly(isobutenylsuccinic anhydride). Such compounds can be used, for example, for emulsification and/or lubrication purposes, and/or as corrosion inhibiting agents. Such compounds can also be used in some cases to control foaming, and/or provide stability to hard water, for example, when included into a metalworking fluid formulation. Other embodiments are generally directed to fluids containing such compounds, which may be used for metalworking or other applications, methods for making or using such compounds, kits including such compounds, or the like.

    Abstract translation: 本发明一般涉及用于金属加工和其他应用的流体，并且特别涉及可用于这种流体中的化合物。 例如，本发明的一些方面通常涉及包含多齿酸（及其衍生物），聚亚烷基二醇和酸酐（例如烷基和/或链烯基琥珀酸酐，和/或其衍生物）的分子化合物，其可以反应 一起例如共价地形成用于这种流体的化合物。 多齿酸的一个例子是偏苯三酸; 聚亚烷基二醇的一个例子是聚乙二醇; 酸酐的一个例子是聚（异丁烯基琥珀酸酐）。 例如，这种化合物可用于乳化和/或润滑目的，和/或作为腐蚀抑制剂。 这些化合物也可以在一些情况下用于控制发泡，和/或为硬水提供稳定性，例如当被包含在金属加工液配制剂中时。 其他实施方案通常涉及含有这样的化合物的流体，其可用于金属加工或其他应用，制造或使用此类化合物的方法，包括此类化合物的试剂盒等。

    COOLING COMPOUNDS
    6.
    发明申请
    COOLING COMPOUNDS 审中-公开
    冷却化合物

    公开(公告)号：WO2008151460A3

    公开(公告)日：2010-04-01

    申请号：PCT/CH2008000266

    申请日：2008-06-11

    Applicant: GIVAUDAN SA ,  FURRER STEFAN MICHAEL ,  YEP GREGORY L ,  FLAMME ERIC

    Inventor： FURRER STEFAN MICHAEL ,  YEP GREGORY L ,  FLAMME ERIC

    IPC: A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61Q11/00 ,  C07C69/38 ,  C07C69/40 ,  C07C229/12

    CPC classification number: A61Q11/00 ,  A61K8/37 ,  A61K8/41 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/244 ,  C07C69/38 ,  C07C69/40 ,  C07C229/12 ,  C07C2602/42

    Abstract: A cooling composition comprising at least one compound of the Formula (I) in which R is selected from the group of moieties consisting of (CH2)nCOOR''; (CH2)nCONMe2; (CH2)nOR''; and CHNH2CH3; where n is 1 - 3 and R'' is independently selected from hydrogen, methyl and ethyl; and R' is selected from the group consisting of the moieties fenchyl, D-bornyl, L-bornyl, exo-norbornyl, 2-methylisobornyl, 2-ethylfenchyl, 2-methylbornyl, cis-pinan-2-yl, verbanyl and isobornyl. The compositions are useful in providing cooling sensations to the skin or mucous membranes of the body.

    Abstract translation: 一种冷却组合物，其包含至少一种式（I）化合物，其中R选自由（CH 2）n COOR“组成的部分; （CH 2）nCONMe2; （CH 2）NOR ''; 和CHNH 2 CH 3; 其中n为1-3，R“独立地选自氢，甲基和乙基; 并且R'选自萜烯基，D-冰片基，L-冰片基，外降冰片基，2-甲基异山梨醇基，2-乙基枞基，2-甲基戊酰基，顺式 - 蒎烷-2-基，缬氨酰基和异冰片基。 该组合物可用于向身体的皮肤或粘膜提供冷却感。

    EFFICIENT COALESCING AGENTS
    7.
    发明申请
    EFFICIENT COALESCING AGENTS 审中-公开
    有效的结合剂

    公开(公告)号：WO2009099948A3

    公开(公告)日：2009-10-29

    申请号：PCT/US2009032658

    申请日：2009-01-30

    Applicant: RHODIA ,  ZHOU LICHANG ,  KOLTISKO BERNARD ,  PAKENHAM DEREK ,  RUIZ JOSE ,  CHEN PU ,  AYMES CHARLES ,  MILLER KERI

    Inventor： ZHOU LICHANG ,  KOLTISKO BERNARD ,  PAKENHAM DEREK ,  RUIZ JOSE ,  CHEN PU ,  AYMES CHARLES ,  MILLER KERI

    IPC: C07C69/44 ,  C07C69/40 ,  C07C69/42

    CPC classification number: C09D5/024 ,  C08K5/11 ,  C09D7/47

    Abstract: A coalescent composition for coating compositions such as paints, adhesives, and coatings comprising a blend of diesters, the blend comprising adducts of alcohol and diacids, the alcohol selected from the group consisting of ethyl, propyl, isopropyl alcohol and mixtures thereof, and the diacids selected from the group consisting of a blend of adipic, glutaric and succinic diacids ('AGS') and a blend of adipic, methylglutaric, and ethylsuccinic diacids ('MGA'), and paint, adhesive, and coating compositions comprising such coalescent compositions are disclosed.

    Abstract translation: 用于涂料组合物如涂料，粘合剂和包含二酯混合物的涂料的聚结剂组合物，所述共混物包含醇和二酸的加合物，所述醇选自乙基，丙基，异丙醇及其混合物，以及所述二酸 选自由己二酸，戊二酸和琥珀酸二酸（'AGS'）和己二酸，甲基戊二酸和乙基琥珀酸二酸（'MGA'）的混合物组成的组，以及包含这种聚结剂组合物的涂料，粘合剂和涂料组合物是 披露。

    EFFICIENT COALESCING AGENTS
    8.
    发明申请
    EFFICIENT COALESCING AGENTS 审中-公开
    有效的结合剂

    公开(公告)号：WO2009099948A2

    公开(公告)日：2009-08-13

    申请号：PCT/US2009/032658

    申请日：2009-01-30

    Applicant: RHODIA, INC. ,  ZHOU, Lichang ,  KOLTISKO, Bernard ,  PAKENHAM, Derek ,  RUIZ, Jose ,  CHEN, Pu ,  AYMES, Charles ,  MILLER, Keri

    Inventor： ZHOU, Lichang ,  KOLTISKO, Bernard ,  PAKENHAM, Derek ,  RUIZ, Jose ,  CHEN, Pu ,  AYMES, Charles ,  MILLER, Keri

    IPC: C07C69/44 ,  C07C69/42 ,  C07C69/40

    CPC classification number: C09D5/024 ,  C08K5/11 ,  C09D7/47

    Abstract: A coalescent composition for coating compositions such as paints, adhesives, and coatings comprising a blend of diesters, the blend comprising adducts of alcohol and diacids, the alcohol selected from the group consisting of ethyl, propyl, isopropyl alcohol and mixtures thereof, and the diacids selected from the group consisting of a blend of adipic, glutaric and succinic diacids ('AGS') and a blend of adipic, methylglutaric, and ethylsuccinic diacids ('MGA'), and paint, adhesive, and coating compositions comprising such coalescent compositions are disclosed.

    Abstract translation: 用于涂料组合物如涂料，粘合剂和包含二酯共混物的涂料的聚结剂组合物，所述共混物包含醇与二酸的加合物，所述醇选自乙基，丙基，异丙基 醇和它们的混合物，以及选自己二酸，戊二酸和琥珀酸二酸（'AGS'）和己二酸，甲基戊二酸和乙基琥珀酸二酸（'MGA'）的混合物的二酸和油漆，粘合剂， 并公开了包含这种聚结剂组合物的涂料组合物。

    ALDEHYDE-RELEASING COMPOUNDS
    9.
    发明申请
    ALDEHYDE-RELEASING COMPOUNDS 审中-公开
    甲醛释放化合物

    公开(公告)号：WO0228345A3

    公开(公告)日：2007-11-29

    申请号：PCT/AU0101254

    申请日：2001-10-05

    Applicant: UNIV TROBE ,  UNIV BAR ILAN ,  UNIV TEL AVIV ,  PHILLIPS DONALD RALPH ,  CUTTS SUZANNE MARGARET ,  REPHAELI ADA ,  NUDELMAN ABRAHAM

    Inventor： PHILLIPS DONALD RALPH ,  CUTTS SUZANNE MARGARET ,  REPHAELI ADA ,  NUDELMAN ABRAHAM

    IPC: A61K31/19 ,  A61K31/203 ,  A61K31/21 ,  A61K31/53 ,  A61K45/06 ,  A61P35/00 ,  C07C59/125 ,  C07C59/305 ,  C07C69/003 ,  C07C69/28 ,  C07C69/36 ,  C07C69/40 ,  C07F9/09 ,  C12N15/12

    CPC classification number: A61K45/06 ,  C07C69/003 ,  C07C69/28 ,  C07C69/36 ,  C07C69/40

    Abstract: A method of treating cancer, comprising the step of administering to a subject in need thereof an effective amount of a compound or compounds which increase or supplement the intracellular levels of endogenous aldehyde, prior to, together with, or subsequent to the administration of a therapeutically-effective amount of a chemotherapeutic agent such as anthracyclines and anthracenediones, wherein the efficacy of the chemotherapeutic agent is enhanced relative to the efficacy of the chemotherapeutic agent alone. The compound may be an aldehyde-releasing compound (preferably formaldehyde), including known aldehyde-releasing compounds and two new classes of aldehyde-releasing compounds. One new class of aldehyde-releasing compounds of formula (II) release more than one equivalent of aldehyde Z-(L-M 1 -CHR-M 2 ) x (II) wherein x is an integer of 2 or more Z is a direct bond or a linking group of valency x; L is either a direct bond or a spacer group R is H or C1-4 alkyl, alkenyl or alkynyl; M 1 is a decomposable or hydrolysable group; and M 2 is a second decomposable or hydrolysable group. Another new class of aldehyde-releasing compounds include a radical based on an inhibitor of an aldehyde detoxifying agent, such as buthionine sulphoximine or crotonaldehyde.

    Abstract translation: 一种治疗癌症的方法，包括以下步骤：在有需要的受试者之前，在施用治疗性疾病之前，之后或之后施用有效量的增加或补充内源性醛的细胞内水平的化合物或化合物 - 化学治疗剂如蒽环类和蒽环类化合物的有效量，其中化疗剂的功效相对于单独的化学治疗剂的功效增强。 化合物可以是释放醛的化合物（优选甲醛），包括已知的释放醛的化合物和两种新类型的释放醛的化合物。 一类新的醛释放式（II）的化合物释放出多于一当量的醛Z-（LM 1 - ）-CHR-M 2 O 2， （II）其中x是2或更大的整数Z是直接键或价数x的连接基团; L是直接键或间隔基R是H或C 1-4烷基，烯基或炔基; M 1是可分解的或可水解的基团; 和M 2是第二个可分解或可水解的基团。 另一种新的醛释放化合物包括基于醛解毒剂抑制剂的基团，例如丁硫氨酸亚磺酰亚胺或巴豆醛。

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