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1.发明申请A TRIPLE CO-CULTURE MODEL OF THE BLOOD-BRAIN BARRIER USING PRIMARY PORCINE BRAIN ENDOTHELIAL CELLS, PORCINE PERICYTES AND PORCINE ASTROCYTES 审中-公开使用原始PORCINE脑内皮细胞，PORCINE PERICYTES和PORCINE ASTROCYTES的血脑屏障的三重共培养模型
公开(公告)号：WO2016202343A1
公开(公告)日：2016-12-22
申请号：PCT/DK2016/050190
申请日：2016-06-16
Applicant: AALBORG UNIVERSITET
Inventor： THOMSEN, Louiza Bohn , LARSEN, Annette Burkhart , MOOS, Torben
CPC classification number: C12N5/0622 , C12N5/0691 , C12N2502/081 , C12N2502/086 , G01N33/5058 , G01N33/5064
Abstract: The present invention relates to an in vitro blood-brain-barrier (BBB) model comprising a porcine triple co-culture comprising porcine astrocytes, porcine primary brain endothelial cells (BEC's) and porcine pericytes. The invention also relates methods of producing such porcine triple co-cultures and uses thereof.
Abstract translation: 本发明涉及一种体外血脑屏障（BBB）模型，其包含包含猪星形胶质细胞，猪原代脑内皮细胞（BEC）和猪周细胞的猪三重共培养物。 本发明还涉及生产这种猪三重共培养物的方法及其用途。
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