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公开(公告)号：WO2019046330A1
公开(公告)日：2019-03-07
申请号：PCT/US2018/048388
申请日：2018-08-28
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , WEBER, Olivia D. , BUZARD, Daniel J. , SHAGHAFI, Michael B.
IPC: A61K31/27 , A61K31/435 , A61K31/438 , C07D295/205 , C07D403/04 , C07D471/10
Abstract: Provided herein are compounds and compositions useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
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公开(公告)号：WO2018093949A1
公开(公告)日：2018-05-24
申请号：PCT/US2017/061870
申请日：2017-11-15
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , BUZARD, Daniel J. , SHAGHAFI, Michael B.
IPC: C07D498/08 , C07D471/10 , C07D295/205 , C07D403/04 , C07D295/26
Abstract: Provided herein are spirocyclic and fused bicyclic carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
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公开(公告)号：WO2018093946A1
公开(公告)日：2018-05-24
申请号：PCT/US2017/061867
申请日：2017-11-15
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , BUZARD, Daniel J. , WHITE, Nicole S. , HERTZOG, Donald L.
IPC: C07D498/08 , C07D471/10 , C07D295/205 , C07D403/04 , C07D295/26
Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
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公开(公告)号：WO2018217809A1
公开(公告)日：2018-11-29
申请号：PCT/US2018/033964
申请日：2018-05-22
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , WEBER, Olivia D. , BUZARD, Daniel J. , SHAGHAFI, Michael B. , WIENER, John J. M. , CISAR, Justin S. , DUNCAN, Katharine K.
IPC: A61K31/415 , A61K31/4155 , A61K31/495 , C07D247/00 , C07D401/12 , C07D403/08
Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
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Patent Agency Ranking
公开(公告)号：WO2018053447A1
公开(公告)日：2018-03-22
申请号：PCT/US2017/052106
申请日：2017-09-18
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , BUZARD, Daniel J. , SHAGHAFI, Michael B. , WEBER, Olivia D.
IPC: C07D295/096 , A61K31/495
Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
Abstract translation: 本文提供哌嗪氨基甲酸酯和包含所述化合物的药物组合物。 主题化合物和组合物可用作MAGL和/或ABHD6的调节剂。 此外，主题化合物和组合物可用于治疗疼痛。
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公开(公告)号：WO2019222266A1
公开(公告)日：2019-11-21
申请号：PCT/US2019/032289
申请日：2019-05-14
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , BUZARD, Daniel J. , SHAGHAFI, Michael B.
IPC: A61K31/41 , A61K31/4164 , A61K31/4192
Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
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公开(公告)号：WO2019046318A1
公开(公告)日：2019-03-07
申请号：PCT/US2018/048372
申请日：2018-08-28
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , WEBER, Olivia D. , BUZARD, Daniel J. , SHAGHAFI, Michael B. , JONES, Todd K.
IPC: A61K31/27 , A61K31/435 , A61K31/438 , C07D295/205 , C07D403/04 , C07D471/10
Abstract: Provided herein are compounds and compositions useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
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公开(公告)号：WO2018093947A1
公开(公告)日：2018-05-24
申请号：PCT/US2017/061868
申请日：2017-11-15
Applicant: ABIDE THERAPEUTICS, INC.
Inventor： GRICE, Cheryl A. , BUZARD, Daniel J. , SHAGHAFI, Michael B.
IPC: C07D498/08 , C07D471/10 , C07D295/205 , C07D403/04 , C07D295/26
Abstract: Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
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公开(公告)号：WO2017197192A1
公开(公告)日：2017-11-16
申请号：PCT/US2017/032276
申请日：2017-05-11
Applicant: ABIDE THERAPEUTICS, INC. , BUZARD, Daniel J. , SHAGHAFI, Michael B.
Inventor： BUZARD, Daniel J. , SHAGHAFI, Michael B. , CISAR, Justin S. , GRICE, Cheryl A. , JONES, Todd K. , WEBER, Olivia D.
IPC: C07D471/10 , A61K31/4747 , A61P25/04
Abstract: Provided herein are spirocycle compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
Abstract translation: 本文提供了螺环化合物和包含所述化合物的药物组合物。 主题化合物和组合物可用作MAGL和/或ABHD6的调节剂。 此外，主题化合物和组合物可用于治疗疼痛。
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