公开(公告)号：WO2018039610A1

公开(公告)日：2018-03-01

申请号：PCT/US2017/048698

申请日：2017-08-25

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： BOWER, Jeffrey ,  ALAILIMA, Titiimaea ,  JOHNSON, Jason ,  MARTUCCI, Walter Edward ,  SLABY, Isabella ,  OMERNICK, Matthew ,  PIPER, Adam ,  PIERCE, Paul Rand ,  MATEUS, Ashley ,  KELLOGG, Scott

IPC: A61B5/16 ,  A61B5/00 ,  G09B5/00 ,  G09B7/00

Abstract: Example systems, methods, and apparatus, including cognitive platforms, are provided for computing performance metrics of an individual based at least in part on user interaction(s) with computerized tasks and/or interference and at least one physiological measure of the individual, where the performance metric provides an indication of the cognitive abilities of the individual. The apparatus can be coupled to at least one physiological component to perform the physiological measurement of the individual. The apparatus also can be configured to adapt the tasks and/or interferences to enhance the individual's cognitive abilities.

Abstract translation: 提供了包括认知平台的示例系统，方法和装置，用于至少部分地基于与计算机化任务和/或干扰的用户交互来计算个体的性能度量，并且至少 个人的一种生理指标，其中表现指标提供个体认知能力的指示。 该设备可以耦合到至少一个生理部件以执行个体的生理测量。 该装置还可以被配置为适应任务和/或干扰以提高个人的认知能力。

公开(公告)号：WO2020081617A1

公开(公告)日：2020-04-23

申请号：PCT/US2019/056405

申请日：2019-10-15

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： ALAILIMA, Titiimaea

IPC: A61B5/00

Abstract: Adaptive modification and presentment of user interface elements in a computerized therapeutic treatment regimen. Embodiments of the present disclosure provide for non-linear computational analysis of cData and nData derived from user interactions with a mobile electronic device executing an instance of a computerized therapeutic treatment regimen. The cData and nData may be computed according to one or more artificial neural network or deep learning technique to derive patterns between computerized stimuli or interactions and sensor data. Patterns derived from analysis of the cData and nData may be used to define an effort metric associated with user input patterns in response to the computerized stimuli or interactions being indicative of a measure of user engagement or effort. A computational model or rules engine may be applied to adapt, modify, configure or present one or more graphical user interface elements in a subsequent instance of the computerized therapeutic treatment regimen.

公开(公告)号：WO2019035910A1

公开(公告)日：2019-02-21

申请号：PCT/US2018/000179

申请日：2018-08-15

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： ALAILIMA, Titiimaea ,  BOWER, Jeffrey ,  JOHNSON, Jason ,  MATEUS, Ashley ,  ESPINOSA, Elena, Canadas ,  PIPER, Adam ,  OMERNICK, Matthew ,  COLLINS, David

IPC: G09B5/02 ,  H04L29/08

Abstract: Apparatus, systems, and methods are provided for generating a quantified indicator of cognitive skills in an individual. In certain configurations, the apparatus, systems, and methods can be implemented for enhancing cognitive skills in an individual.

公开(公告)号：WO2019028376A1

公开(公告)日：2019-02-07

申请号：PCT/US2018/045206

申请日：2018-08-03

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： ALAILIMA, Titiimaea ,  BOWER, Jeffery ,  MARTUCCI, Walter, E. ,  MATEUS, Ashley ,  SLABY, Isabella ,  OMERNICK, Matthew ,  PIPER, Adam ,  PIERCE, Paul, Rand ,  KELLOGG, Scott ,  ESPINOSA, Elena, Cañadas

IPC: A61B5/04 ,  A61B5/00

Abstract: Apparatus, systems and methods are provided for quantifying aspects of cognition (including cognitive abilities) under emotional load. In certain configurations, the apparatus, systems and methods can be implemented for enhancing certain cognitive abilities.

公开(公告)号：WO2018222729A1

公开(公告)日：2018-12-06

申请号：PCT/US2018/035155

申请日：2018-05-30

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： ALAILIMA, Titiimaea ,  TREES, Jason ,  MATEUS, Ashley ,  JOHNSON, Jason ,  BERGO, Mark ,  PIPER, Adam ,  DOELLER, Christian ,  SPIERS, Hugo

IPC: A61B5/00 ,  A61B5/055 ,  A61B5/16 ,  A61N1/36

CPC classification number: A61N1/08 ,  A61B5/00 ,  A61B5/055 ,  A61B5/16 ,  A61B5/4082 ,  A61B5/4088 ,  A61B5/744 ,  A61N1/36025 ,  G16H20/70 ,  G16H50/20

Abstract: Apparatus, systems and methods for generating an assessment of one or more cognitive abilities in an individual by analyzing measurement data collected from measurements of the physical actions of the individual in interacting with computerized tasks involving spatial navigation including one or more of way-finding, path-plotting, route-learning, or path integration. The analysis is used to provide a performance metric indicative of the cognitive ability of the individual, and optionally to generate an indication of a neurodegenerative condition of the individual.

公开(公告)号：WO2018132483A1

公开(公告)日：2018-07-19

申请号：PCT/US2018/013182

申请日：2018-01-10

Applicant: AKILI INTERACTIVE LABS, INC. ,  BOWER, Jeffrey ,  ALAILIMA, Titiimaea

Inventor： BOWER, Jeffrey ,  ALAILIMA, Titiimaea

IPC: A61B5/04

CPC classification number: A61B5/4082 ,  A61B5/0022 ,  A61B5/021 ,  A61B5/024 ,  A61B5/04 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/053 ,  A61B5/14542 ,  A61B5/162 ,  A61B5/163 ,  A61B5/168 ,  A61B5/4088 ,  A61B5/7475 ,  G16H10/20 ,  G16H20/70 ,  G16H50/20 ,  G16H50/30

Abstract: Example systems, methods, and apparatus are provided for using data collected from the responses of an individual with the computerized tasks of a cognitive platform to derive performance metrics as an indicator of cognitive abilities, and applying predictive models to the performance metrics and data indicative of one or both of the individual's age and gender to generate an indication of neurodegenerative condition. The example systems, methods, and apparatus also can be configured to adapt the computerized tasks to enhance the individual's cognitive abilities, and for using data collected from the responses of the individual with the adapted computerized tasks to derive performance metrics and applying predictive models to the performance metrics and data indicative of one or both of the individual's age and gender to generate the indication of neurodegenerative condition.

公开(公告)号：WO2021150717A1

公开(公告)日：2021-07-29

申请号：PCT/US2021/014364

申请日：2021-01-21

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： TREES, Jason ,  ALAILIMA, Titiimaea

IPC: A61B5/00 ,  G06F11/3466 ,  G06F11/3612 ,  G06F11/3616 ,  G06F17/18 ,  G16H10/20

Abstract: Systems and methods for distributed scientific evaluation of software product comprising a digital health intervention or software as a medical device product. In certain embodiments, a scientific evaluation system is operably configured to analyze one or more safety, efficacy, performance, and/or quality assurance aspects for program code outputs of the software product. In further embodiments, a scientific evaluation system is operably configured to configure and administer a distributed scientific evaluation, research study and/or clinical trial for the software product. In certain embodiments, a scientific evaluation system is configured to enable scientific evaluation of one or more program code outputs of a software product for one or more indication or intended use.

公开(公告)号：WO2018112103A1

公开(公告)日：2018-06-21

申请号：PCT/US2017/066214

申请日：2017-12-13

Applicant: AKILI INTERACTIVE LABS, INC. ,  MATEUS, Ashley ,  ALAILIMA, Titiimaea ,  JOHNSON, Jason ,  OMERNICK, Matthew ,  DOELLER, Christian ,  SPIERS, Hugo ,  MARTUCCI, Walter Edward

Inventor： MATEUS, Ashley ,  ALAILIMA, Titiimaea ,  JOHNSON, Jason ,  OMERNICK, Matthew ,  DOELLER, Christian ,  SPIERS, Hugo ,  MARTUCCI, Walter Edward

IPC: G06Q50/00

Abstract: A cognitive platform is disclosed that is configured for either or both of assessing or enhancing the cognitive abilities of an individual based on implementing one or more navigation task(s) in an environment. A first task is rendered that requires the individual to rely on allocentric navigation capabilities to navigate in the environment based on a first set of views of portions of the environment rendered at the user interface. A second task is rendered that requires the individual to rely on egocentric navigation capabilities to navigate in the environment. An indication of a cognitive ability in the individual can be generated based on the difference in the individual's performance at the first task as compared to the second task.

公开(公告)号：WO2018081134A1

公开(公告)日：2018-05-03

申请号：PCT/US2017/058103

申请日：2017-10-24

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： BOWER, Jeffrey ,  ALAILIMA, Titiimaea

IPC: A61B5/16 ,  A61B5/00 ,  G09B5/00

Abstract: Example systems, methods, and apparatus are provided for using data collected from the responses of an individual with the computerized tasks of a cognitive platform to derive performance metrics as an indicator of cognitive abilities, and applying predictive models to generate an indication of neurodegenerative condition. The example systems, methods, and apparatus also can be configured to adapt the computerized tasks to enhance the individual's cognitive abilities, and for using data collected from the responses of an individual with the adapted computerized tasks to derive performance metrics and applying predictive models to generate the indication of neurodegenerative condition.

Abstract translation: 提供了示例系统，方法和装置，用于使用从个人对认知平台的计算机化任务的响应中收集的数据来推导作为认知能力的指标的性能度量，并且应用预测模型 以产生神经变性症状的指征。 示例系统，方法和装置还可以被配置为适应计算机化任务以增强个体的认知能力，并且使用从具有适应的计算机化任务的个体的响应收集的数据来导出性能度量并应用预测模型来生成 神经退行性病症的征兆。

公开(公告)号：WO2018027080A1

公开(公告)日：2018-02-08

申请号：PCT/US2017/045385

申请日：2017-08-03

Applicant: AKILI INTERACTIVE LABS, INC.

Inventor： ALAILIMA, Titiimaea ,  BOWER, Jeffrey ,  MARTUCCI, Walter Edward ,  MATEUS, Ashley ,  SLABY, Isabella ,  OMERNICK, Matthew ,  PIPER, Adam ,  PIERCE, Paul Rand ,  KELLOGG, Scott ,  ESPINOSA, Elena Cañadas

IPC: G09B5/00 ,  G09B7/00 ,  G09B15/00 ,  H04L29/08

Abstract: An apparatus for generating a quantifier of cognitive skills in an individual includes a user interface, a memory to store processor-executable instructions, and a processing unit communicatively coupled to the user interface and the memory. Upon execution of the processor-executable instructions by the processing unit, the processing unit is configured to: render a first instance of a task with an interference at the user interface, requiring a first response from the individual to the first instance of the task in the presence of the interference and a response from the individual to at least one evocative element. One or more of the first instance of the task and the interference comprises the at least one evocative element. The user interface is configured to measure data indicative of the response of the individual to the at least one evocative element, the data comprising at least one measure of emotional processing capabilities of the individual under emotional load. The apparatus is configured to measure substantially simultaneously the first response from the individual to the first instance of the task and the response from the individual to the at least one evocative element. The processing unit is further configured to receive data indicative of the first response and the response of the individual to the at least one evocative element. The processing unit is further configured to analyze the data indicative of the first response and the response of the individual to the at least one evocative element to compute at least one performance metric comprising at least one quantified indicator of cognitive abilities of the individual under emotional load.

Abstract translation: 用于在个体中产生认知技能的量化者的设备包括用户界面，用于存储处理器可执行指令的存储器以及可通信地耦合到用户界面和存储器的处理单元。 在处理单元执行处理器可执行指令后，处理单元被配置成：在用户界面处呈现具有干扰的任务的第一实例，需要来自个人的第一响应到第一任务的第一实例 干扰的存在以及个体对至少一个唤起元素的响应。 任务的第一个实例和干扰中的一个或多个包括至少一个启发元素。 用户界面被配置为测量指示个人对至少一个唤起元素的响应的数据，所述数据包括在情绪负荷下个体的情绪处理能力的至少一个度量。 该装置被配置为基本上同时测量从个体到任务的第一实例的第一响应以及从个体到至少一个启示性元素的响应。 处理单元还被配置为接收指示第一响应和个体对至少一个启示性元素的响应的数据。 处理单元进一步被配置为分析指示第一响应的数据和个体对至少一个促发因素的响应的数据以计算至少一个性能度量，该至少一个性能度量包括情绪负载下个体的至少一个认知能力的量化指标