公开(公告)号：WO2019137985A1

公开(公告)日：2019-07-18

申请号：PCT/EP2019/050518

申请日：2019-01-10

申请人： ALLINKY BIOPHARMA

发明人： VEGA GARCÍA, Miguel ,  CAMPOS MUELAS, Pedro ,  CARRASCO ROMERO, Esther ,  BURGUETE PÉREZ, Asunción ,  GÓMEZ GUTIÉRREZ, Patricia ,  PÉREZ GONZÁLEZ, Juan Jesús ,  MESSEGUER PEYPOCH, Ángel ,  ALARCÓN SÁNCHEZ, Balbino José ,  ARELLANO ROJO, Irene Azhara

IPC分类号： C07D405/14 ,  C07D413/14 ,  C07D217/24 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  C07D487/04 ,  A61P35/00 ,  A61K31/4725 ,  A61K31/472

CPC分类号： C07D487/04 ,  A61P35/00 ,  C07D217/24 ,  C07D401/12 ,  C07D405/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12

摘要： The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.

公开(公告)号：WO2021005165A1

公开(公告)日：2021-01-14

申请号：PCT/EP2020/069403

申请日：2020-07-09

申请人： ALLINKY BIOPHARMA

发明人： VEGA GARCÍA, Miguel ,  CAMPOS MUELAS, Pedro ,  CARRASCO ROMERO, Esther ,  BURGUETE PÉREZ, Asunción ,  GÓMEZ GUTIÉRREZ, Patricia ,  PÉREZ GONZÁLEZ, Juan Jesús ,  MESSEGUER PEYPOCH, Ángel ,  ALARCÓN SÁNCHEZ, Balbino José

IPC分类号： C07D413/12 ,  C07D217/06 ,  C07D217/14 ,  C07D217/16 ,  A61P35/00 ,  A61K31/472 ,  A61K31/4725

摘要： The present invention relates to a novel class of tetrahydroisoquinoline compounds of formula I and to compositions comprising the same. The compounds and compositions of the present invention can be used as medicaments in the treatment of cancer.