公开(公告)号：WO2014144680A2

公开(公告)日：2014-09-18

申请号：PCT/US2014029195

申请日：2014-03-14

Applicant: AMERICAN PEAT TECHNOLOGY LLC ,  UNIV MINNESOTA

Inventor： KOLOMITSYN IGOR V ,  JONES PEGGY WALLGREN ,  GREEN DOUGLAS A

IPC: B27M1/08 ,  B23P23/04 ,  B27C9/00

CPC classification number: B01J20/3078 ,  B01J20/20 ,  B01J20/3021 ,  B01J20/3085 ,  B01J2220/485 ,  B01J2220/4887 ,  C02F1/286 ,  C02F1/42 ,  C02F2001/425 ,  C02F2101/20 ,  C02F2303/16

Abstract: A process for the preparation from a partially decomposed organic material like peat a granulated or pelletized sorption medium using low-temperature, thermal activation of the sorption medium to produce a high degree of granule or pellet hardness balanced against an efficacious level of ion-exchange and adsorption capacity, followed by chemical treatment of the thermally-activated sorption material via an acid solution and a salt solution to increase its ion-exchange and adsorption performance while minimizing the transfer of natural impurities found in the sorption medium to an aqueous solution is provided by this invention. The sorption medium of this invention can be used in a variety of aqueous solution treatment processes, such as wastewater treatment.

Abstract translation: 一种由部分分解的有机材料制成的方法，如泥炭，颗粒状或造粒的吸附介质，使用吸附介质的低温热活化，以产生与有效水平的离子交换平衡的高度颗粒或丸粒硬度， 吸附能力，然后通过酸溶液和盐溶液对热活化吸附材料进行化学处理，以提高其离子交换和吸附性能，同时使吸附介质中发现的天然杂质的转移最小化为水溶液，由 本发明。 本发明的吸附介质可用于各种水溶液处理工艺，如废水处理。

公开(公告)号：WO2005047304A3

公开(公告)日：2005-11-10

申请号：PCT/US2004038252

申请日：2004-11-10

Applicant: UNIV MINNESOTA ,  KRASUTSKY PAVEL A ,  KOLOMITSYNA OKSANA ,  KRASUTSKYY DMYTRO A ,  KACHAROV OLEKSIY D ,  KOLOMITSYN IGOR V

Inventor： KRASUTSKY PAVEL A ,  KOLOMITSYNA OKSANA ,  KRASUTSKYY DMYTRO A ,  KACHAROV OLEKSIY D ,  KOLOMITSYN IGOR V

IPC: A61K31/00 ,  C07C29/86 ,  C07J63/00 ,  A61K35/78 ,  A61K7/00

CPC classification number: C07J63/00

Abstract: The present invention provides a method for obtaining a natural product (e.g., betulin, lupeol and/or betulinic acid) from a plant extract (e.g., birch bark extract). The method employs a distillation with water and an organic solvent that (i) is water-immiscible, (ii) is capable of forming an azeotropic mixture with water, or (iii) has a boiling point of at least 100°C (e.g., toluene) and an aqueous base (e.g., KOH).

Abstract translation: 本发明提供了从植物提取物（例如桦树皮提取物）获得天然产物（例如桦木醇，羽扇豆醇和/或桦木酸）的方法。 该方法使用水和有机溶剂进行蒸馏，所述有机溶剂（i）与水不混溶，（ii）能够与水形成共沸混合物，或（iii）具有至少100℃的沸点（例如， 甲苯）和碱水溶液（例如KOH）。

公开(公告)号：WO2007121352A3

公开(公告)日：2008-08-28

申请号：PCT/US2007066632

申请日：2007-04-13

Applicant: UNIV MINNESOTA ,  KRASUTSKY PAVEL A ,  KOLOMITSYN IGOR V ,  HOLY JON M ,  PERKINS EDWARD LEON ,  PACKEE EDMOND C ,  KOLOMITSYNA OKSANA

Inventor： KRASUTSKY PAVEL A ,  KOLOMITSYN IGOR V ,  HOLY JON M ,  PERKINS EDWARD LEON ,  PACKEE EDMOND C ,  KOLOMITSYNA OKSANA

IPC: A61K31/56

CPC classification number: A61K36/185 ,  A61K31/56

Abstract: The present invention relates generally to compositions that can be obtained by extraction of birch bark, methods of using such compositions (e.g., methods of medical use, cosmetic use and/or pharmaceutical use), food products and methods of manufacturing such compounds. The compositions are triterpenes, triterpene alcohols, or derivatives of triterpene alcohols.

Abstract translation: 本发明一般涉及通过提取桦树皮获得的组合物，使用这种组合物的方法（例如，医疗用途，化妆品用途和/或药物用途），食品和制造这些化合物的方法。 组合物是三萜烯，三萜醇或三萜醇的衍生物。

公开(公告)号：WO02098924A3

公开(公告)日：2003-08-28

申请号：PCT/US0218082

申请日：2002-06-05

Applicant: UNIV MINNESOTA ,  KRASUTSKY PAVEL A ,  CARLSON ROBERT M ,  KOLOMITSYN IGOR V ,  WANG HONG

Inventor： KRASUTSKY PAVEL A ,  CARLSON ROBERT M ,  KOLOMITSYN IGOR V ,  WANG HONG

IPC: C07B39/00 ,  C07C409/00 ,  C07C409/34 ,  C07C331/00

CPC classification number: C07C409/34 ,  C07B39/00

Abstract: Methods of making compositions including fluorinated peroxides are disclosed. The compositions are useful, for example, for reacting with organic compounds. In one embodiment, novel peroxides are provided.

Abstract translation: 公开了制备包括氟化过氧化物的组合物的方法。 组合物可用于例如与有机化合物反应。 在一个实施方案中，提供了新的过氧化物。

公开(公告)号：WO0110885A3

公开(公告)日：2001-09-27

申请号：PCT/US0021829

申请日：2000-08-10

Applicant: UNIV MINNESOTA ,  KRASUTSKY PAVEL A ,  CARLSON ROBERT M ,  NESTERENKO VITALIY V ,  KOLOMITSYN IGOR V ,  EDWARDSON CHRIS F

Inventor： KRASUTSKY PAVEL A ,  CARLSON ROBERT M ,  NESTERENKO VITALIY V ,  KOLOMITSYN IGOR V ,  EDWARDSON CHRIS F

IPC: C07D301/32 ,  B01D11/00 ,  C07C29/76 ,  C07C29/86 ,  C07C35/44 ,  C07C51/367 ,  C07C51/43 ,  C07C51/47 ,  C07C59/01 ,  C07C59/105 ,  C07C62/06 ,  C07D303/38 ,  C07J63/00 ,  D21B1/02 ,  C07C59/10 ,  C08L61/06

CPC classification number: C07D303/38 ,  C07C29/86 ,  C07C51/367 ,  C07C51/43 ,  C07C59/01 ,  C07C59/105 ,  C07J63/008 ,  D21B1/023 ,  C07C31/10 ,  C07C31/08 ,  C07C31/04

Abstract: The invention provides methods for separating outer birch bark from inner birch bark. The invention also provides methods for isolating betulin; lupeol; betulinic acid; 9,10-epoxy-18-hydroxyoctadecanoic acid; 9,10,18-trihydroxyoctadecanoic acid; polyphenolic polymers and fatty acids from birch bark.

Abstract translation: 本发明提供了用于从白桦树皮分离外桦树皮的方法。 本发明还提供了分离桦木醇的方法; 羽扇豆醇; 桦木酸; 9,10-环氧-18-羟基十八烷酸; 9,10,18-三羟基十八烷酸; 多酚聚合物和来自桦树皮的脂肪酸。