公开(公告)号：WO2021081321A1

公开(公告)日：2021-04-29

申请号：PCT/US2020/057054

申请日：2020-10-23

Applicant: AMGEN INC.

Inventor： POMPE, Cornelius ,  CLARK, Nicholas, J. ,  QI, Wei ,  MCAULEY, Arnold, J. ,  SCHNEIDER, Michael ,  WU, Chia-Jung ,  CHRISTIAN, Twinkle, R. ,  FRANEY, Heather, N. ,  JAGANNATHAN, Bharadwaj ,  ABEL, Jeffrey ,  DIETZEL, Franz

IPC: G01N24/08 ,  G01N33/15 ,  A61M5/142

Abstract: An approach for determining material compatibility for components of a drug delivery system is provided that includes using surface zeta-potential analytical method to evaluate surface interactions between a desired molecule and at least one material present within a given IV-bag system.

公开(公告)号：WO2020167910A1

公开(公告)日：2020-08-20

申请号：PCT/US2020/017874

申请日：2020-02-12

Applicant: AMGEN INC.

Inventor： CLARK, Nicholas, J. ,  WU, Chia-Jung ,  EU, Mingda ,  ALANIS, Artemio, A. ,  SAWICKY, Jennifer, Lyn ,  GOSS, Monica, Michelle ,  STEVENSON, Jennifer ,  FRANEY, Heather, N. ,  PIEDMONTE, Deirdre ,  BRYCH, Stephen, Robert

IPC: A61J1/20 ,  A61M39/00

Abstract: An approach for preparing a drug delivery device includes providing a prefilled delivery container and transferring a drug product contained in a drug container to the prefilled delivery container. The prefilled delivery container includes a container body containing a predetermined quantity of saline solution and a predetermined quantity of IV stabilizing solution ("IVSS"). The drug product is transferred to the prefilled delivery container via a delivery container adapter.