公开(公告)号：WO2003020333A2

公开(公告)日：2003-03-13

申请号：PCT/US2002/027314

申请日：2002-08-28

Applicant: ARTEMIS MEDICAL, INC.

Inventor： DUBRUL, William, R. ,  BUEHLMANN, Eric, L. ,  SMITH, Jeffrey, A. ,  SCHOLL, John, A. ,  HIRD, Barbara, A.

IPC: A61M

CPC classification number: A61B10/02 ,  A61B10/0096 ,  A61B10/0233 ,  A61B10/0275 ,  A61B17/3211 ,  A61B17/322 ,  A61B2017/008 ,  A61B2017/320008 ,  G01N1/04 ,  G01N1/06

Abstract: A tissue sample collection assembly collects undamaged cells from a tissue specimen comprising a damaged tissue layer at a margin thereof. The assembly includes a tissue-severing device used to separate at least a portion of the damaged tissue layer. The tissue-severing device may have a tissue-adhesive surface so that undamaged cells may contact and adhere to the tissue-adhesive surface for subsequent analysis. The assembly may comprise an apertured device comprising inner and outer surfaces with apertures passing therebetween. The apertures may be sized and shaped so that when the inner surface of the apertured device is pressed against a tissue specimen, portions of an undamaged tissue layer of the tissue specimen pass through the apertures and past the outer surface so that the tissue-severing device can sever the undamaged tissue layer portions from the remainder of the tissue specimen. Exposed undamaged tissue may adhere to a tissue-adhesive surface of the tissue-severing device.

Abstract translation: 组织样本收集组件从包括其边缘处的受损组织层的组织标本收集未损伤的细胞。 该组件包括用于分离损伤的组织层的至少一部分的组织切断装置。 组织切断装置可以具有组织粘合剂表面，使得未损坏的细胞可以接触并粘附到组织粘合剂表面用于随后的分析。 组件可以包括有孔装置，其包括内表面和外表面，孔之间通过。 孔可以被定尺寸和成形，使得当有孔装置的内表面被压在组织样本上时，组织样本的未损伤的组织层的部分通过孔并经过外表面，使得组织切断装置 可以从组织样本的其余部分切断未损坏的组织层部分。 暴露的未损伤的组织可能粘附到组织切断装置的组织粘合剂表面。

公开(公告)号：WO2004043240A3

公开(公告)日：2004-05-27

申请号：PCT/US2003/036355

申请日：2003-11-12

Applicant: ARTEMIS MEDICAL, INC.

Inventor： MARION, Duane, W. ,  MORRISON, George, A. ,  SCHOLL, John, A. ,  SMITH, Jeffrey, A.

IPC: A61B18/18

Abstract: An electrosurgical electrode assembly having a cutting device including a catheter with a proximal and distal end, and an electrode carried on the distal end of the catheter. A controller is connected to the cutting device. A data acquisition system is connected to the controller and is capable of monitoring voltage and current output. A microprocessor may also be connected to the data acquisition system for processing voltage and current data from the data acquisition system. A generator is also connected to the data acquisition system. The controller initiates movement of the electrode upon arc initiation at the electrode. Methods of using the devices herein are also disclosed.