公开(公告)号：WO2019152854A1

公开(公告)日：2019-08-08

申请号：PCT/US2019/016373

申请日：2019-02-01

Applicant: AYTU BIOSCIENCE, INC. ,  ACERUS BIOPHARMA INC.

Inventor： WESTFIELD, Gerwin ,  ZWIERKO, Margaux ,  RAMASAMY, Ranjith ,  BRYSON, Nathan

IPC: A61K31/568 ,  A61M5/20 ,  A61M5/30

Abstract: Methods and systems for preventing or reducing side effects of testosterone replacement therapy (TRT) by administering a testosterone formulation multiple times per day are disclosed. The methods of the present invention enable men who cannot tolerate previous TRT regimens, e.g. because they wish to attempt to conceive or are at risk of developing cardiovascular side effects, to receive TRT treatment.