公开(公告)号：WO2014182635A1

公开(公告)日：2014-11-13

申请号：PCT/US2014/036865

申请日：2014-05-05

Applicant: BALDWIN, Megan, E. ,  LASHKARI, Kameran ,  MA, Jie

Inventor： BALDWIN, Megan, E. ,  LASHKARI, Kameran ,  MA, Jie

IPC: G01N33/68

CPC classification number: G01N33/74 ,  A61K9/0048 ,  A61K38/179 ,  A61K38/45 ,  A61K39/395 ,  C12Y207/10001 ,  G01N33/68 ,  G01N2333/475 ,  G01N2800/16 ,  G01N2800/164 ,  G01N2800/50 ,  G01N2800/52 ,  G01N2800/7014

Abstract: The present application is directed to the use of a VEGF-C inhibitor, a VEGFR-2 inhibitor and/or a VEGFR-3 inhibitor as a prophylactic or therapeutic for the treatment of eye disorders such as a maculopathy and pathogenic ocular neovascularisation. The application is also directed to the use of a VEGF-C measurement from a biological sample from a mammalian subject as a predictive marker, a selected marker, a responsive marker or a tracking marker for a disease or condition selected from the group consisting of a maculopathy and pathogenic ocular neovascularization.

Abstract translation: 本申请涉及使用VEGF-C抑制剂，VEGFR-2抑制剂和/或VEGFR-3抑制剂作为预防或治疗用于治疗眼部疾病如黄斑病变和致病性眼新生血管形成。 本申请还涉及使用来自哺乳动物受试者的生物样品的VEGF-C测量作为预测标记，所选标记，响应性标记或用于选自以下的疾病或病症的追踪标记： 黄斑病变和致病性眼新生血管形成。

公开(公告)号：WO2013131237A1

公开(公告)日：2013-09-12

申请号：PCT/CN2012/071949

申请日：2012-03-05

Applicant: XINGYUNRONGCHUANG (BEIJING) INFORMATION TECHNOLOGY COMPANY LIMITED ,  MA, Jie ,  FENG, Jinghui

Inventor： MA, Jie ,  FENG, Jinghui

IPC: H04L29/08 ,  H04L9/00

CPC classification number: G06F21/6218

Abstract: A computer-implemented method may be provided. The method may be performed by a server system having one or more servers and memory storing one or more programs for execution by the one or more servers. The method may comprise, at the server system: receiving an access request to a network server from a terminal device; determining whether the access request matches a cached record stored in an substitute server; if the cached record is found, returning the cached record to the terminal device; if no cached record is found, processing the access request for security check; forwarding the processed access request to the network server; receiving a response from the network server; optimizing the response from the network server; and forwarding the optimized response to the terminal device.

Abstract translation: 可以提供计算机实现的方法。 该方法可以由具有一个或多个服务器的服务器系统和存储一个或多个用于一个或多个服务器执行的程序的存储器执行。 该方法可以包括在服务器系统处：从终端设备接收对网络服务器的访问请求; 确定所述访问请求是否匹配存储在替换服务器中的缓存记录; 如果发现缓存的记录，则将缓存的记录返回到终端设备; 如果没有找到缓存记录，则处理访问请求进行安全检查; 将处理的访问请求转发到网络服务器; 从网络服务器接收响应; 优化网络服务器的响应; 并将优化的响应转发到终端设备。