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公开(公告)号：WO2008157111A2
公开(公告)日：2008-12-24
申请号：PCT/US2008/066304
申请日：2008-06-09
发明人： LAI, Yu-Chin , LANG, Weihong , QUINN, Edmond, T.
CPC分类号： C07F7/0854 , C08F283/12 , C08F290/068 , C08G18/0814 , C08G18/672 , C08G77/14 , C08G77/20 , C08G77/458 , C08G2210/00 , C08L53/00 , C08L53/005 , C08L83/10 , G02B1/043 , C08L51/085 , C08G18/61 , C08L2666/02
摘要： Prepolymers comprising at least one block of Formula II and terminated with a polymerizable ethylenically unsaturated radical are useful in hydrogel materials are disclosed: wherein n, R, R 1 , R 2 and X + are as defined herein.
摘要翻译： 包含至少一个式II的嵌段和用可聚合的烯属不饱和基团封端的预聚物可用于水凝胶材料：其中n，R，R1，R2和X +如本文所定义。
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2.发明申请
公开(公告)号：WO2006007252A1
公开(公告)日：2006-01-19
申请号：PCT/US2005/019137
申请日：2005-06-01
发明人： LAI, Yu-Chin , QUINN, Edmond, T.
IPC分类号： C08F290/06
CPC分类号： A61L27/16 , A61L27/18 , C08F290/068 , G02B1/043 , C08L51/085 , C08L35/00 , C08L67/06
摘要： Provided are a novel class of fumaric- and itaconic-containing prepolymers and compositions comprising the prepolymers used in the manufacture of medical devices.
摘要翻译： 提供了一类新颖的含富马酸和衣康酸的预聚物和包含用于制造医疗器械的预聚物的组合物。
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3.发明申请
公开(公告)号：WO2005056625A1
公开(公告)日：2005-06-23
申请号：PCT/US2004/040213
申请日：2004-12-01
发明人： LAI, Yu-Chin , QUINN, Edmond, T.
IPC分类号： C08F290/06
CPC分类号： C08G77/388 , A61L27/18 , C08F230/08 , C08F283/12 , C08F290/06 , C08F290/068 , C08G77/38 , C08L51/085 , G02B1/043 , C08L75/04 , C08L2666/02
摘要： Provided are novel reactive functionalized fumaric- and itaconic-containing prepolymers and compositions comprising the prepolymers used in the manufacture of medical devices. The prepolymers can be used to provide surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to reactive, hydrophilic polymers.
摘要翻译： 提供了新型的反应性官能化富马酸和含衣康酸的预聚物和包含用于制造医疗装置的预聚物的组合物。 预聚物可用于提供由具有与反应性亲水性聚合物互补的反应性官能度的一种或多种富马酸或含有衣康酸的预聚物形成的表面改性隐形眼镜。
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公开(公告)号：WO2007075604A1
公开(公告)日：2007-07-05
申请号：PCT/US2006/048302
申请日：2006-12-19
CPC分类号： G02B1/043 , B29D11/00125
摘要： A process for producing polymeric biomedical devices, such as contact lenses, involves casting a monomeric mixture including a diluent; and subsequently removing extractables from the devices by contacting the devices with the an additional volume of the diluent.
摘要翻译： 用于生产聚合物生物医学装置（例如隐形眼镜）的方法包括浇铸包含稀释剂的单体混合物; 并随后通过使装置与额外体积的稀释剂接触从装置中除去可提取物。
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5.发明申请POLYMERIC RADIATION-ABSORBING MATERIALS AND OPHTHALMIC DEVICES COMPRISING SAME 审中-公开聚合物辐射吸收材料和包含其的光学器件
公开(公告)号：WO2007050394A2
公开(公告)日：2007-05-03
申请号：PCT/US2006/040704
申请日：2006-10-18
发明人： LAI, Yu-Chin , QUINN, Edmond, T.
CPC分类号： G02B1/043 , A61F2/145 , A61F2002/16965 , C08F220/18 , C08F220/26 , C08F220/40 , C08F226/10 , C08F230/08 , C08L43/04
摘要： A polymeric radiation-absorbing material comprises units of a polymerizable benzotriazole-based radiation-absorbing compound and a monomer, and is capable of absorbing UV radiation, at least about 90 percent of light having wavelength of 425 nm, less than about 50 percent of light having wavelength of 450 nm, and less than about 30 percent of light having wavelength of 475 nm. Ophthalmic devices, such as contact lenses, corneal rings, corneal inlays, keratoprostheses, and intraocular lenses, are made from such polymeric material.
摘要翻译： 聚合物辐射吸收材料包含可聚合苯并三唑类辐射吸收化合物和单体的单元，并且能够吸收紫外线辐射，至少约90％的波长为425nm，小于约50％的光 具有450nm的波长和小于约30％的波长为475nm的光。 诸如隐形眼镜，角膜环，角膜嵌体，角膜假体和眼内透镜的眼科装置由这种聚合材料制成。
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公开(公告)号：WO2005056651A1
公开(公告)日：2005-06-23
申请号：PCT/US2004/040217
申请日：2004-12-01
发明人： LAI, Yu-Chin , QUINN, Edmond, T.
IPC分类号： C08J7/04
CPC分类号： C08G77/38 , A61L27/34 , G02B1/043 , C08L51/085 , C08L83/04
摘要： Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to reactive hydrophilic polymers.
摘要翻译： 提供由具有与反应性亲水聚合物互补的反应性官能度的一种或多种富马酸或含衣康酸的预聚物形成的表面改性隐形眼镜。
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7.发明申请POLYSILOXANES AND POLYSILOXANE PREPOLYMERS WITH VINYL OR EPOXY FUNCTIONALITY 审中-公开具有乙烯基或环氧官能团的多异氰酸酯和聚硅氧烷预聚物
公开(公告)号：WO2009111296A1
公开(公告)日：2009-09-11
申请号：PCT/US2009/035429
申请日：2009-02-27
申请人： BAUSCH & LOMB INCORPORATED , LAI, Yu-Chin , QUINN, Edmond, T. , LANG, Weihong , NUNEZ, Ivan, M.
IPC分类号： C08G77/14 , C08G77/16 , C08G77/20 , C08G77/26 , C08G77/54 , C08G18/10 , C08G18/61 , C08G18/67
CPC分类号： C08G77/16 , C08G18/10 , C08G18/61 , C08G18/672 , C08G77/14 , C08G77/20 , C08G77/458
摘要： Polysiloxanes having vinyl or epoxy functionality. The polysiloxanes are used to form polymer-based materials having properties particularly suited for biomedical device applications. The polysiloxanes are of general formula (I).
摘要翻译： 具有乙烯基或环氧官能团的聚硅氧烷。 聚硅氧烷用于形成具有特别适用于生物医学装置应用的特性的聚合物基材料。 聚硅氧烷为通式（I）。
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公开(公告)号：WO2009070443A1
公开(公告)日：2009-06-04
申请号：PCT/US2008/083159
申请日：2008-11-12
申请人： BAUSCH & LOMB INCORPORATED , LAI, Yu-Chin , QUINN, Edmond, T. , LANG, Weihong , AMMON, Daniel, M. , KUNZLER, Jay, Friedrich
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , A61L27/18 , A61L27/34 , B29D11/00067 , C08L83/04
摘要： A process for treating a silicone hydrogel biomedical device, especially an ophthalmic lens such as a contact lens, involves: immersing the silicone hydrogel biomedical device with a mixture of an organic solvent and a hydrophilic, polymeric material, for a sufficient time that the device is swollen in volume by at least 30%; and removing the organic solvent from the device while retaining at least a portion of the hydrophilic polymeric material therein.
摘要翻译： 用于处理硅酮水凝胶生物医学装置，特别是诸如隐形眼镜的眼用透镜的方法包括：将硅酮水凝胶生物医学装置与有机溶剂和亲水性聚合物材料的混合物浸渍足够的时间，使该装置为 体积膨胀至少30％; 并从装置中除去有机溶剂，同时将至少一部分亲水性聚合物材料保持在其中。
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公开(公告)号：WO2007078762A3
公开(公告)日：2007-07-12
申请号：PCT/US2006/047510
申请日：2006-12-13
摘要： A process for removing extractables from biomedical devices, particularly ophthalmic biomedical devices, involves contacting the device with a mixture of first and second extractants. The first extractant is an organic compound having a flash point above 38°C, and the second extractant is an organic compound having a flash point below 38°C.
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10.发明申请RADIATION-ABSORBING POLYMERIC MATERIALS AND OPHTHALMIC DEVICES COMPRISING SAME 审中-公开辐射吸收性聚合物材料和包含它们的眼科装置
公开(公告)号：WO2007050395A2
公开(公告)日：2007-05-03
申请号：PCT/US2006/040705
申请日：2006-10-18
发明人： LAI, Yu-Chin , QUINN, Edmond, T.
CPC分类号： A61F2/145 , A61F2002/16965 , C08F220/14 , C08F220/26 , C08F220/60 , C08F222/1006 , C09B69/106 , G02B1/041 , G02B1/043
摘要： A radiation-absorbing polymeric material comprises units of a polymerizable UV-absorbing compound, a violet light-absorbing compound, and a monomer, and is capable of absorbing UV radiation, at least about 90 percent of light having wavelength of 425 nm, less than about 50 percent of light having wavelength of 450 nm, and less than about 30 percent of light having wavelength of 475 nm. Ophthalmic devices, such as contact lenses, corneal rings, corneal inlays, keratoprostheses, and intraocular lenses, are made from such polymeric material.
摘要翻译： 辐射吸收聚合材料包含可聚合的UV吸收化合物，紫光吸收化合物和单体的单元，并且能够吸收UV辐射，至少约90％的光 具有425nm的波长，小于约50％的波长为450nm的光，以及小于约30％的波长为475nm的光。 诸如隐形眼镜，角膜环，角膜嵌体，角膜假体和眼内透镜之类的眼科装置由这种聚合物材料制成。
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