公开(公告)号：WO2020154292A1

公开(公告)日：2020-07-30

申请号：PCT/US2020/014412

申请日：2020-01-21

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

Inventor： DESBROSSES, Freddy ,  PADULA, Pierpaolo ,  DESRIAUX, Marjorie ,  ABDESSALEM, Yannis ,  PORQUERAS, Diego Santo-Domingo

IPC: A61J1/20

Abstract: A reconstitution device includes a body, a first piercing member located at a first end of the body, and a receptacle located at the second end of the body. The receptacle includes a collar configured to engage a vial, and a cap extending from the collar and holding a second piercing member. The second piercing member is disposed within the collar. The reconstitution device includes a first fluid pathway formed within and extending from the first piercing member to the second piercing member. The reconstitution device includes a second fluid pathway formed within and extending from the second piercing member to a portion of the body between the first piercing member and the second piercing member.

公开(公告)号：WO2022251810A1

公开(公告)日：2022-12-01

申请号：PCT/US2022/072505

申请日：2022-05-23

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

Inventor： DESBROSSES, Freddy ,  PADULA, Pierpaolo ,  DUPONT, Caroline Roselyne ,  DEMULIER, Marin Anh-Thuan ,  BOUREZG, Zouaoui

IPC: A61K9/00 ,  A61K47/02

Abstract: The invention relates to a flexible container/multi-chamber container with selective dissolved gas content for stabilizing at least one compound of a medical product having a selective gas requirement for remaining stable, comprising a solution comprising the at least one compound and a fil material from which the container is made that provides for high gas-barrier for the said gas. The at least one compound may be selenium in the form of Se(IV) and is preferably selected from the group consisting of sodium selenite, selenous acid and selenium dioxide. The selective gas may be oxygen, and the headspace of the oxygen maintains the solution to comprise dissolved oxygen (DO) at a level of 0.5 ppm to 8 ppm.

公开(公告)号：WO2022251106A1

公开(公告)日：2022-12-01

申请号：PCT/US2022/030517

申请日：2022-05-23

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

Inventor： BOUREZG, Zouaoui ,  DUPONT, Caroline Roselyne ,  DESBROSSES, Freddy ,  COUTHOUIS, Aurélie ,  BROSSARD, Gabriel ,  PADULA, Pierpaolo ,  TROUILLY, Jean-Luc

IPC: A23L33/00 ,  A23L33/115 ,  A23L33/125 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/175 ,  B65D81/32 ,  A61J1/20

Abstract: The present disclosure relates to a terminally heat-sterilized ready-to-use parenteral nutrition formulation comprising all macronutrients and micronutrients required to meet the clinical guidelines for parenteral nutrition, wherein all said micronutrients and macronutrients are provided in one multi-chamber bag (MCB). The disclosure is also directed to a parenteral nutrition formulation comprising all such macronutrients and micronutrients. More specifically, the present disclosure is directed to a MCB comprising at least five chambers containing a carbohydrate formulation in a first chamber, an amino acid formulation in a second chamber, a lipid formulation in a third chamber, a fourth chamber comprising a vitamin formulation and a fifth chamber comprising a trace element formulation, wherein the carbohydrate formulation, amino acid formulation and/or the lipid formulation may also contain certain vitamins and certain trace elements that can be stably accommodated therein.

公开(公告)号：WO2019245960A1

公开(公告)日：2019-12-26

申请号：PCT/US2019/037468

申请日：2019-06-17

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

Inventor： DESBROSSES, Freddy ,  PADULA, Pierpaolo ,  ABDESSALEM, Yannis ,  DESRIAUX, Marjorie ,  PORQUERAS, Diego Santo-Domingo

IPC: A61J1/20

Abstract: A reconstitution device includes a first piercing member, a second piercing member, and a receptacle. The first piercing member has a first end and a second end. The first end of the first piercing member is configured to engage an administration port. The first piercing member includes a first fluid pathway extending from the first end of the first piercing member to the second end of the first piercing member. The receptacle includes a collar and a cap. The collar is configured to engage a vial. The cap extends from the collar and holds the second piercing member. A first end of the second piercing member is disposed within the collar.

公开(公告)号：WO2019032934A1

公开(公告)日：2019-02-14

申请号：PCT/US2018/046165

申请日：2018-08-10

Applicant: BAXTER INTERNATIONAL INC. ,  BAXTER HEALTHCARE SA

Inventor： DESBROSSES, Freddy ,  PADULA, Pierpaolo ,  MANTA, Virgil Claudiu ,  CHAMPAIN, Valentin

IPC: A61J1/20

Abstract: A reconstitution device includes: a piercing member (30) having a first end (32) and a second end (34), the first end of the piercing member configured to engage an administration port; a delivery member (40) having a first end (42) and a second end (44), the first end of the delivery member configured to engage a delivery site; a collar (20) configured to engage a vial (25); and a cap (22) extending from the collar (20) and holding the piercing member (30) and the delivery member (40) such that the second end (34) of the piercing member and the second end (44) of the delivery member are disposed within the cylindrical collar (20).