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1.发明申请
公开(公告)号：WO2017192407A1
公开(公告)日：2017-11-09
申请号：PCT/US2017/030268
申请日：2017-04-28
CPC分类号： A61K9/5026 , A61K8/11 , A61K9/5031 , A61K31/565 , A61K2800/10 , A61K2800/412 , A61Q19/00 , B01J13/16 , C05G3/00
摘要： The present invention relates a microcapsule that comprises an active pharmaceutical ingredient and a polymeric shell comprised of polymeric materials such as polyether, polyester, polyamine, polyamide, polyurea, polyurethane, polythiocarbamate, and polythiocarbonate. The outer surface of shell comprises surface functional groups such as hydroxide, primary amine, carboxylic acid, or protected forms thereof. These surface functional groups may be reacted further with reactants to place specific organic groups on the surface of the microcapsule. Such microcapsules are prepared by a modified interfacial condensation polymerization.
摘要翻译： 本发明涉及包含活性药物成分和聚合物壳的微胶囊，所述聚合物壳由聚合物材料例如聚醚，聚酯，聚胺，聚酰胺，聚脲，聚氨酯，聚硫代氨基甲酸酯和聚硫代碳酸酯组成。 壳的外表面包含表面官能团，例如氢氧根，伯胺，羧酸或其保护形式。 这些表面官能团可以进一步与反应物反应以在微胶囊的表面上放置特定的有机基团。 这种微胶囊通过改性界面缩聚制备。
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公开(公告)号：WO2020168359A1
公开(公告)日：2020-08-20
申请号：PCT/US2020/022223
申请日：2020-03-12
摘要： The present invention is directed to a dental hygiene appliance, a pad usable in such an appliance, and a method of using such an appliance. The dental hygiene appliance comprises a plurality of mushroom-shaped bristles, wherein the mushroom-shaped bristles comprise a material with Shore 00 hardness between about 50 and about 100. The mushroom-shaped bristles comprise a stipe, a pileus, and optionally a brim. The dental hygiene appliance may be a monolithic body, or comprises a monofacial pad, or bifacial pad, that is held by a dental hygiene appliance frame. The advantage of having a brim is that it offers a larger area for dental hygiene appliance to interact with the tooth surface, and the brim allows the brim to get into crevices of teeth that are too small for pileus to enter. The interstitial space between the mushroom-shaped bristles may also comprise a dentifrice composition.
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公开(公告)号：WO2010059324A2
公开(公告)日：2010-05-27
申请号：PCT/US2009/061147
申请日：2009-10-19
发明人： JOYCE, Peter, J. , BIELSKI, Roman
CPC分类号： B01D53/04 , B01D53/70 , B01D53/82 , B01D2253/102 , B01D2257/206
摘要： An alkyl halide such as methyl bromide can be effectively removed from a gas stream by passing the gas stream through a bed of adsorbent at a relatively low temperature to adsorb the alkyl halide onto the adsorbent, desorbing the alkyl halide at a higher temperature to produce a smaller volume of gas containing the alkyl halide in more concentrated form, and then reacting the alkyl halide with a nucleophile contained in a liquid phase by contacting this smaller gas volume with such liquid phase.
摘要翻译： 通过使气流在相对低的温度下通过吸附剂床，可以有效地从气流中除去烷基卤，例如甲基溴，以将烷基卤吸附到吸附剂上，在较高温度下解吸烷基卤，生成 较小体积的含有更浓缩形式的烷基卤的气体，然后通过使该较小的气体体积与这种液相接触使烷基卤与包含在液相中的亲核试剂反应。
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公开(公告)号：WO2006057749A2
公开(公告)日：2006-06-01
申请号：PCT/US2005/038305
申请日：2005-10-24
发明人： JOYCE, Peter, J. , BIELSKI, Roman
CPC分类号： B01J4/001 , B01D53/70 , B01D2251/21 , B01D2257/2062 , B01J19/24
摘要： Alkyl halides can be effectively scrubbed from gas streams containing them by passing the gas streams through dispersers having a very small pore size into an aqueous scrubbing liquid containing a nucleophile such as thiosulfate. Optionally, the addition of a water-soluble organic compound to the scrubbing liquid may increase the rate of destruction of the alkyl halide. Alkyl halides such as methyl bromide can be effectively scrubbed from enclosed spaces containing the halide, for example in enclosures used for fumigation.
摘要翻译： 通过使气流通过具有非常小的孔径的分散器进入含有亲核试剂如硫代硫酸盐的水性洗涤液体中，可以从含有它们的气流中有效地洗涤卤代烷。 任选地，向洗涤液中加入水溶性有机化合物可增加烷基卤化物的破坏速率。 烷基卤化物如甲基溴可以从包含卤化物的封闭空间，例如用于熏蒸的外壳中有效地洗涤。
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