公开(公告)号：WO2022189636A1

公开(公告)日：2022-09-15

申请号：PCT/EP2022/056349

申请日：2022-03-11

申请人： BIOMEDCODE HELLAS SA

发明人： GEORGE, Kollias ,  NIKI, Karagianni ,  MARIA C., Denis ,  ALEXIOS N., Matralis ,  DIMITRA, Papadopoulou ,  ELENI, Karkoulia

IPC分类号： C07D295/145 ,  C07D213/73 ,  C07D471/04 ,  C07D241/44 ,  A61K31/5375 ,  A61K31/54 ,  A61P29/00

摘要： The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, hydrate, or isomer thereof. The invention also provides pharmaceutical compositions comprising the compounds of formula (I) as well as their use in therapy, particularly in the treatment of inflammatory conditions. Advantageously, the compounds of the invention show a broad and robust anti-inflammatory effect, and are therapeutically safe.