-
公开(公告)号：WO9842310A3
公开(公告)日：1998-12-23
申请号：PCT/EP9801831
申请日：1998-03-20
IPC分类号： A61K9/20 , A61K31/192 , A61K9/00
CPC分类号： A61K9/2054 , A61K9/2009 , A61K9/2018 , A61K9/2059 , A61K31/192
摘要： A fast-release homogeneous compressed tablet composition comprising: (i) 1-50 % by weight flurbiprofen or a pharmaceutically acceptable salt thereof; and (ii) 50-99 % by weight compressible carrier material comprising a disintegrant and a compressible component selected from a sugar component, a starch component and an alkaline earth metal component; characterised in that the compressible carrier material further comprises microcrystalline cellulose present in a ratio to said compressible component of 1:4 to 4:1 parts by weight; and further characterised in that the crushing strength of the tablet is in the range 5-15 Kgf and that the disintegration time is less than 10 minutes.
摘要翻译： 一种快速释放均质压制片剂组合物，其包含：（i）1-50重量％的氟比洛芬或其药学上可接受的盐; 和（ii）50-99重量％的可压缩载体材料，其包含崩解剂和选自糖组分，淀粉组分和碱土金属组分的可压缩组分; 其特征在于所述可压缩载体材料还包含与所述可压缩组分的比例为1：4至4：1重量份的微晶纤维素; 其特征还在于片剂的抗碎强度在5-15Kgf范围内，崩解时间小于10分钟。
-
公开(公告)号：WO2010122358A3
公开(公告)日：2011-03-24
申请号：PCT/GB2010050674
申请日：2010-04-23
CPC分类号： A61K9/0095 , A61K47/26 , A61K47/36
摘要： The present invention provides a chewable oral delivery system and, in particular, a chewable tablet which can deliver pharmaceutical, therapeutic or nutritional ingredients. The system is based on a combination of non-digestible oligo and polysaccharide fibres. The oligosaccharide is substantially soluble in water at in-mouth conditions providing for quick solubilisation of the tablet. The polysaccharide is substantially insoluble in water at in-mouth conditions, but is wettable and dispersible in such conditions. Preferred oligosaccharides are oligofructose, polydextrose andgalacto-oligosaccharides or a mixture of them. The preferred polysaccharide is a linear chain fructan, preferably inulin.
摘要翻译： 本发明提供了可咀嚼的口服递送系统，特别是可提供药物，治疗或营养成分的咀嚼片。 该系统基于不消化的寡糖和多糖纤维的组合。 寡糖在口服条件下基本上可溶于水，从而使片剂快速溶解。 多糖在口服条件下基本上不溶于水，但在这种条件下是可湿性和可分散的。 优选的寡糖是低聚果糖，聚右旋糖和半乳寡糖或它们的混合物。 优选的多糖是直链果聚糖，优选菊糖。
-
公开(公告)号：WO2010122357A3
公开(公告)日：2011-03-31
申请号：PCT/GB2010050673
申请日：2010-04-23
CPC分类号： A61K9/0095 , A61K47/26 , A61K47/36
摘要： The present invention provides a delivery system for active and functional ingredients. In particular, the delivery systems of the present invention find particular application in the delivery of active and functional ingredients, such as medicaments, pharmaceuticals, nutritional supplements, botanicals, cosmeceuticals etc. Further, the invention relates to a delivery system for oral or topical administration of such active and functional ingredients. The invention is a delivery system based on a particulate gel precursor that acts both as the bodying agent,as well as the dispersing and suspending agent in the formulation. By modifying the level of precursor and process conditions, a broad range of product consistencies can be achieved ranging from thin liquid suspension to firm or semi solid gel. The precursor gel is a particulate linear chain fuctan gel. Inulin is a preferred fructan.
摘要翻译： 本发明提供了一种用于活性和功能成分的递送系统。 特别地，本发明的递送系统特别适用于递送活性和功能成分，例如药物，药物，营养补充剂，植物药，药妆等。此外，本发明涉及用于口服或局部给药的递送系统 的这种活性和功能成分。 本发明是一种基于颗粒状凝胶前体的递送系统，它既起主体作用，也用作制剂中的分散和悬浮剂。 通过改变前体和工艺条件的水平，可以实现范围广泛的产品一致性，从薄液体悬浮液到固体或半固体凝胶。 前体凝胶是颗粒状直链状的果糖凝胶。 菊粉是优选的果聚糖。
-
-
搜索结果
3 条记录 (耗时 0.051 秒)
