Abstract:
An anchor configured to maximize the surface area of the anchor to improve anchor retention is disclosed. The anchor may be configured with a width that differs from a thickness of the anchor. In some embodiments, the anchor be configured as a helical ribbon defining a central lumen about a central axis extending through the helical ribbon. The helical ribbon may vary in width, thickness, central lumen diameter, or a combination thereof, along its extent. The anchor may include retention features that are configured to promote tissue and/or implant interaction for improved anchor retention.
Abstract:
An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a first configuration and a second expanded configuration, an occlusive member disposed along at least a portion of an outer surface of the expandable framework and a resilient member coupled to the occlusive member. Further, the resilient member is configured to keep the occlusive member taut against an outer surface of the expandable member in both the first configuration and the second configuration.
Abstract:
An example system for detecting leakage around an implant is disclosed. The example system for detecting leakage around an occlusive implant disposed in the left atrial appendage includes an elongate shaft having a port disposed at a distal end region thereof and a first sensor disposed adjacent the elongate shaft. The elongate shaft is configured to be positioned adjacent the occlusive implant such that the first sensor is positioned on a first side of the occlusive implant and the port is positioned on a second side of the occlusive implant. Further, the first sensor is configured to measure a first parameter and the first parameter is utilized to determine a fluid leak between the occlusive implant and a tissue wall defining the left atrial appendage.
Abstract:
An example introducer is disclosed. An example introducer sheath includes a tubular member (10) including an inner surface (32), an outer surface (34) and a wall (33) extending therebetween. The introducer further includes a plurality of reinforcement members (38). The plurality of reinforcement members are positioned radially inward of the outer surface of the tubular member. Further, each of the plurality of the reinforcement members are positioned radially outward of the inner surface of the tubular member. Additionally, the tubular member is designed to shift from a first configuration to a second configuration and the wall has a first thickness in the first position and a second thickness in the second position, the second thickness smaller than the first thickness.
Abstract:
Catheters with weeping balloons can be used for various medical purposes. For example, in some embodiments provided herein weeping balloons are used for catheter visualization devices. In some embodiments, weeping balloons are used to deliver therapeutic agents. Weeping balloons can include openings of a selected size and shape through which a fluid gradually flows or "weeps." The design of the openings can affect performance characteristics such as, but not limited to, fluid flow rate, tear resistance, and mitigation of counter-flow.
Abstract:
An example introducer is disclosed. An example introducer (10) includes an inner liner (20) including a lumen, a distal region and at least one folded portion extending along the distal region. The introducer also includes a reinforcing member (38) having a length and including at least one spine extending along the length of the reinforcing member. The introducer also includes a sheath (30) disposed along at least a portion of the introducer, wherein the sheath includes at least one perforation (32), wherein material adjacent to the at least one folded portion is removed from a distal portion of the introducer to form a tip region (26). The introducer also includes a tip member (56) disposed along the tip region.
Abstract:
A sensor device for sensing endoluminal geometry may include an expandable element disposed on the distal region of a shaft. The expandable element may be configured to move a collapsed configuration and an expanded configuration. The expandable element may include one or more sensor elements configured to sense proximity of the sensor element to tissue. The sensor device may include an indicator configured to distinguish between contact of the sensor element with tissue, loss of contact and proximity of the sensor element to tissue.
Abstract:
An intravascular catheter and related methods of use or manufacture are disclosed. The catheter includes an outer tubular member having a proximal end and a distal end, and an inner tubular member having a proximal end and a distal end. An inflatable balloon have a proximal end waist coupled to the outer tubular member adjacent to the distal end thereof, and a distal end waist coupled to the inner tubular member adjacent to the distal end thereof. The balloon includes an interior surface, an exterior surface, and a lumen defined by the interior surface. The balloon further includes at least one section extending from the interior surface of the balloon to the exterior surface of the balloon. A transmitter is disposed about the inner tubular member. In addition to the above, the proximal end waist is coupled to the outer tubular member such that an inflation fluid exits the balloon.
Abstract:
A low profile implant, system and method of deployment includes a plurality of anchors supported by a plurality of anchor housings. The anchor housings include one or more release mechanisms configured to affix the frame to the anchor housings during implant deployment, actuation and cinching, and to release the frame following cinching to enable the frame to be withdrawn from the treatment site.
Abstract:
An implant (800) for occluding a left atrial appendage (13) may include an expandable framework (160, 805) configured to shift between a collapsed configuration and an expanded configuration, an occlusive element disposed on the expandable framework, and a sealing member (40, 802) spaced apart proximally from the expandable framework by a gap distance (195). A system for occluding a left atrial appendage (13) may further include a delivery sheath and a core wire releasably secured to the implant (800). A method for occluding a left atrial appendage (13) may include advancing the implant (800) to the left atrial appendage (13), deploying the expandable framework (160, 805) within the left atrial appendage (13), shifting the expandable framework (160, 805) into the expanded configuration within the left atrial appendage (13), and deploying the sealing member (40,802) proximate an ostium of the left atrial appendage (13).