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公开(公告)号：WO2021113125A1
公开(公告)日：2021-06-10
申请号：PCT/US2020/062041
申请日：2020-11-24
发明人： SMITH, Amanda , MAGUE, Jennifer , LYDECKER, Lauren , PIC, Andrew
摘要： A medical device includes a sheath having a proximal end, a distal end, and at least one lumen extending from the proximal end to the distal end, and a balloon at the distal end of the sheath and having an inflated configuration and a deflated configuration. The balloon defines at least one space radially inward of an exterior surface of the balloon, the at least one space configured to retain a material, and the transition of the balloon from the deflated configuration to the inflated configuration delivers the material from the at least one space to a target site in a body.
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公开(公告)号：WO2021108240A1
公开(公告)日：2021-06-03
申请号：PCT/US2020/061443
申请日：2020-11-20
发明人： FAVREAU, John T. , PIC, Andrew
IPC分类号： A61B17/04
摘要： The present disclosure pertains to medical devices. More particularly, the present disclosure pertains to devices, systems, and methods for securing tissue, such as a tissue defect or wound resulting from an endoscopic procedure, e.g., an endoscopic mucosal resection or submucosal dissection procedure. In one example, a device for securing tissue may include a loop portion configured to be disposed about a distal end of a delivery device in a delivery configuration and configured to be secured about the tissue in a deployed configuration. A locking member may be disposed on the loop portion. A tether portion having a proximal end extendable proximally within the delivery device and a distal portion extending from the loop portion slidably through the locking member.
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公开(公告)号：WO2021021536A1
公开(公告)日：2021-02-04
申请号：PCT/US2020/043171
申请日：2020-07-23
IPC分类号： A61B17/12 , A61B1/00 , A61B17/00 , A61B17/064
摘要： The present disclosure pertains to medical devices. More particularly, the present disclosure pertains to a device for closing a wound, such as a tissue defect resulting from an endoscopic mucosal resection or endoscopic submucosal dissection procedure. In one example, a device for closing a wound may include a closure element having a delivery configuration and a deployed configuration, the closure element configured to be disposed about an endcap of an endoscope in a delivery configuration. A release filament may have a distal end releasably coupled to the closure element and a proximal end extendable within the endcap. The closure element may be configured to substantially close about the wound in the deployed configuration.
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公开(公告)号：WO2022061243A1
公开(公告)日：2022-03-24
申请号：PCT/US2021/051132
申请日：2021-09-20
发明人： EVERS, Ryan , CONGDON, Daniel , PIC, Andrew , MURRAY, Collin
摘要： A medical device (20) for delivering a material using a pressurized fluid includes an enclosure (60) having a first chamber (68) and a second chamber (66) separated by a membrane (76), and an outlet, and a pin (70) configured to move within the enclosure between a first position and a second position, where a proximal end of the pin blocks the outlet when the pin is in the first position.
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公开(公告)号：WO2020028297A1
公开(公告)日：2020-02-06
申请号：PCT/US2019/044035
申请日：2019-07-30
发明人： SMITH, Amanda , PIC, Andrew , REBAR, Hannah
IPC分类号： A61B17/00
摘要： Systems and methods of delivering a patch to a target site of a patient are described herein. The patch may comprise a biomaterial such as chitosan or extracellular matrix and may be biocompatible and/or bioresorbable. The system may include an endoscope, a patch, and one of an instrument or a cap, the patch being coupled to the respective instrument or cap and detachable therefrom. Methods of delivering the patch to the target site may include introducing an endoscope into a gastrointestinal tract of a patient, e.g., the patch being in a folded or crimped configuration, navigating a distal end of the endoscope proximate a target site; and applying the patch to the target site while releasing the patch from the endoscope.
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公开(公告)号：WO2019140181A1
公开(公告)日：2019-07-18
申请号：PCT/US2019/013179
申请日：2019-01-11
IPC分类号： A61L31/04 , A61L31/16 , A61L26/00 , A61K31/722
CPC分类号： A61L26/0023 , A61K31/722 , A61L26/0066 , A61L26/008 , A61L31/042 , A61L31/16 , A61L2300/232 , A61L2300/418 , A61L2300/60 , A61L2400/04 , A61M25/09 , A61M2025/091 , A61M2202/064 , A61M2210/1042 , C08L5/08
摘要： In various aspects, the present disclosure pertains to methods of treating or preventing bleeding at a tissue site comprising applying a chitosan powder composition to the tissue site. In various aspects, the present disclosure pertains to chitosan powder compositions for application to a tissue site, where the powder compositions comprise a chitosan salt, a crosslinked chitosan, a derivatized chitosan, or a combination thereof. In various aspects, the disclosure pertains to catheter assemblies, which are preloaded with a chitosan powder composition and which are configured to deliver the chitosan powder composition a tissue site.
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公开(公告)号：WO2023038701A1
公开(公告)日：2023-03-16
申请号：PCT/US2022/036832
申请日：2022-07-12
发明人： PIC, Andrew , KING, Joseph W.
IPC分类号： A61B17/122 , A61B17/128
摘要： A clipping system includes a device including longitudinal slots extending through a wall thereof and a clip releasably received within a distal portion of the device. The clip includes a capsule and a pair of clip arms. Proximal ends of the arms are slidably received within the capsule and a collet is slidably mounted over the device movable between an insertion configuration, in which the collet is positioned over the distal portion of the device pressing the distal portion against the capsule and a deployed configuration, in which the collet is proximal of the distal portion so that the clip is releasable from the device. A control member extends through the channel of the device to couple to the proximal ends of the arms and a portion of the collet. Movement of the member opens and closes the clip and moves the collet between the insertion and deployed configurations.
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公开(公告)号：WO2022236263A1
公开(公告)日：2022-11-10
申请号：PCT/US2022/072077
申请日：2022-05-03
摘要： A delivery device may comprise a sheath (10) configured to be inserted into a body lumen of a patient. The sheath may have a proximal end, a distal end, a first channel extending within the sheath from the proximal end to the distal end, and a second channel extending within the sheath from the proximal end to the distal end. A collective cross-sectional area of the first channel and the second channel may be more than 50% of a total cross sectional area of the sheath. The device may also be comprised of a handle (11) at the proximal end of the sheath, wherein the handle is configured to provide fluid communication between a first port and the first channel and a second port and the second channel.
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公开(公告)号：WO2021173631A1
公开(公告)日：2021-09-02
申请号：PCT/US2021/019363
申请日：2021-02-24
发明人： MURRAY, Collin , KING, Joseph, W. , PIC, Andrew , LYDECKER, Lauren , RYAN, Shawn
IPC分类号： A61M1/00
摘要： A medical system including a porous body connected to a distal end of a vacuum tube, and a patch defining a lumen therethrough for accommodating the vacuum tube, where the patch is fluidly seals the porous body from a body lumen when the patch is deployed in a subject.
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公开(公告)号：WO2021158494A1
公开(公告)日：2021-08-12
申请号：PCT/US2021/016121
申请日：2021-02-02
发明人： LEHTINEN, Laurie, A. , MURRAY, Collin , FREDRICKSON, Gerald , NAM, Ra , CONGDON, Daniel , RAUSA, Joseph , PIC, Andrew , SOUKALOPOULOS, Tony
IPC分类号： A61B17/00
摘要： A medical device that comprises an enclosure defining a cavity for containing an agent, a lumen for receiving a pressurized fluid, a channel between the cavity and the lumen, and a barrier positioned in the channel and defining a space, wherein in a first position of the barrier, the space is in fluid communication with the cavity to receive the agent from the cavity, and wherein the barrier is configured to rotate from the first position to a second position in which the space is in fluid communication with the lumen to deliver the agent from the space to the lumen.
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