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公开(公告)号:WO2022159829A1
公开(公告)日:2022-07-28
申请号:PCT/US2022/013547
申请日:2022-01-24
IPC分类号: A61K38/17 , A61K38/55 , A61K47/18 , A61K47/00 , A61K31/047
摘要: An aqueous formulation includes a PEDF-derived short peptide (PDSP) having the sequence of one of SEQ ID NO: 1, 2, 3, 5, 6, 8, or 9; boric acid at a concentration of 0.01 mM – 923 mM; and a non-ionic tonicity agent. The pH value is around 5.5–8.4. The non-ionic tonicity agent is glycerin, sucrose, mannitol, or sorbitol. A concentration of the PDSP is 0.01% - 1% w/v.