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公开(公告)号：WO2023022671A1
公开(公告)日：2023-02-23
申请号：PCT/TR2021/050825
申请日：2021-08-18
发明人： CAN, Fatih , CELIK, Devrim , YILMAZ, Emine
IPC分类号： A61P11/00 , A61K9/14 , A61K31/045 , A61K31/047 , A61K31/335 , A61K31/365
摘要： The invention relates to a process for the preparation of dry powder pharmaceutical compositions for inhalation. Further, the present invention also relates to dry powder pharmaceutical compositions administered by means of inhaler devices comprising ivermectin as an active agent and at least one pharmaceutically acceptable carrier.
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2.发明申请
公开(公告)号：WO2023283466A1
公开(公告)日：2023-01-12
申请号：PCT/US2022/036589
申请日：2022-07-08
申请人： PTC THERAPEUTICS, INC. , PINNAMANENI, Swathi , DALI, Mandar V. , PATEL, Dhaval , UDDIN, Akm Nasir
IPC分类号： A61K9/107 , A61K31/122 , A61K31/047 , A61K36/63 , A61K36/899 , A61K47/14 , A61K47/26 , A61K47/44 , A61K9/1075 , A61P1/00
摘要： Disclosed herein is pharmaceutical compositions of Compound 1, and/or the hydroquinone form thereof, and methods useful for treating or suppressing a disease or disorder such as an α-synucleinpathy, a tauopathy, an autistic spectrum disorder, a pervasive developmental disorder, a liver disease, and liver damage in a subject using such pharmaceutical compositions.
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3.发明申请
公开(公告)号：WO2022250553A1
公开(公告)日：2022-12-01
申请号：PCT/PL2022/050030
申请日：2022-05-23
发明人： MALEC, Przemysław , ŻBIK, Paweł
IPC分类号： B01D15/32 , B01D11/02 , C07C403/24 , A61K31/047
摘要： The subject of the invention is a method of obtaining high-purity myxoxanthophylls, consisting of solvent extraction using sonication, centrifugation, decantation of the supernatant, obtaining the extract by evaporating the solvent or solvent mixture, purifying the dissolved extract on a chromatographic column, all steps being carried out in the absence of light.
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公开(公告)号：WO2022224820A1
公开(公告)日：2022-10-27
申请号：PCT/JP2022/017131
申请日：2022-03-30
申请人： 国立大学法人鳥取大学 , 株式会社ジーピーシー研究所 , 鳥取県
IPC分类号： C07C35/37 , A23L33/10 , A61K8/31 , A61K8/9728 , A61K31/047 , A61K36/07 , A61P25/20 , A61P43/00 , A61Q19/00 , C07D303/12 , C12N1/14 , C12P7/02
摘要： 本発明は、式Ｉ、式Ｉ'、式ＩＩまたは式ＩＩ'で示される化合物、ならびに該化合物またはツチナメコの培養物を含む概日リズム調節用組成物などを提供する。
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公开(公告)号：WO2022214963A1
公开(公告)日：2022-10-13
申请号：PCT/IB2022/053167
申请日：2022-04-05
申请人： TETS, Victor , TETS, Georgy
发明人： TETS, Victor , TETS, Georgy
IPC分类号： A61K31/315 , A01N47/44 , A01P1/00 , A01P21/00 , A01P3/00 , A23K20/105 , A23K20/111 , A23K20/189 , A23K20/26 , A23K20/30 , A23K50/80 , A61K31/047 , A61K31/198 , A61K31/728 , A61K31/785 , A61K33/30 , A61K33/42 , A61K45/06 , A61K47/32 , A61K9/0014 , A61K9/0048 , A61K9/0063 , A61K9/06 , A61K9/08 , A61P1/02 , A61P27/02 , A61P31/04 , A61P31/10
摘要： The present invention relates to the compounds and methods for controlling living organisms for their bioactivity, improving their habitat in order to increase the biological activity of living beings in various conditions, as well as the prevention and treatment of diseases of plants, animals and humans.
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公开(公告)号：WO2022202403A1
公开(公告)日：2022-09-29
申请号：PCT/JP2022/010902
申请日：2022-03-11
申请人： 花王株式会社
IPC分类号： A61K33/00 , A23L33/125 , A61K8/19 , A61K8/34 , A61K31/047 , A61K47/26 , A61P1/02 , A61P9/12 , A61P21/00 , A61P31/02 , A61P31/04 , A61P43/00 , A61Q11/00
摘要： 口腔内において、ナイセリア・ムコサの含有率を増加するために有用な素材を提供する。 硝酸イオン供給化合物と、エリスリトール、キシリトール及びマンニトールから選ばれる１種以上の糖アルコールを有効成分とする口腔内ナイセリア・ムコサ増加剤。
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公开(公告)号：WO2022182527A1
公开(公告)日：2022-09-01
申请号：PCT/US2022/016001
申请日：2022-02-10
发明人： METCALF, Douglas G.
IPC分类号： A61K9/08 , A61K31/047 , A61K31/045 , A61K47/10 , A61K47/50
摘要： This patent document describes excipients that allow certain bioactive agents that exist as hydrophobic molecules to be reformulated as anions that display improved hydrophilicity, which can improve the bioavailability and pharmacokinetics of broad classes of pharmaceuticals.
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公开(公告)号：WO2022172010A1
公开(公告)日：2022-08-18
申请号：PCT/GB2022/050361
申请日：2022-02-10
发明人： SU, Qun , WANG, Zhiyuan , WU, Xufeng
IPC分类号： A61F6/04 , A61L31/08 , A61K31/047
摘要： The present invention provides a packaged condom comprising a sealed package and, within the package, a condom comprising natural rubber latex and/or synthetic polyisoprene, wherein the condom comprises, on one or more surfaces thereof and in contact with the natural rubber latex and/or synthetic polyisoprene, an aqueous lubricant. The aqueous lubricant comprises a thickener and, in a total amount of from 5 to 25 % by weight of the lubricant, one or more organic compounds independently selected from the group consisting of a polyhydric alcohol and a sugar, each of said one or more organic compounds having at least 4 hydroxyl groups and a molecular weight of from 120 to 10000. The invention further provides a method for preparing a packaged condom, a packaged condom obtainable by or obtained by this method, and the use of the aqueous lubricant to lubricate one or more surfaces of a condom comprising natural rubber latex and/or synthetic polyisoprene while maintaining the transparency of the condom during storage within a sealed package.
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公开(公告)号：WO2022159829A1
公开(公告)日：2022-07-28
申请号：PCT/US2022/013547
申请日：2022-01-24
IPC分类号： A61K38/17 , A61K38/55 , A61K47/18 , A61K47/00 , A61K31/047
摘要： An aqueous formulation includes a PEDF-derived short peptide (PDSP) having the sequence of one of SEQ ID NO: 1, 2, 3, 5, 6, 8, or 9; boric acid at a concentration of 0.01 mM – 923 mM; and a non-ionic tonicity agent. The pH value is around 5.5–8.4. The non-ionic tonicity agent is glycerin, sucrose, mannitol, or sorbitol. A concentration of the PDSP is 0.01% - 1% w/v.
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公开(公告)号：WO2022138871A1
公开(公告)日：2022-06-30
申请号：PCT/JP2021/048037
申请日：2021-12-23
IPC分类号： A61K31/047 , A61K31/375 , A61P17/00 , A61P31/04 , A61P43/00
摘要： 【課題】 抗生物質に頼らず、簡便、安全、且つ、低コストに、黄色ブドウ球菌等やそれらが多剤耐性化したものといった菌が関与する皮膚疾患を効果的に抑制することのできる皮膚疾患改善剤を提供する。 【解決手段】 エリスリトールもしくはキシリトールを有効成分として含有し菌の増殖を抑制することができるので、副作用が懸念される抗生物質に頼らず、簡便、安全、且つ、低コストに、黄色ブドウ球菌などの菌が関与する皮膚疾患を効果的に抑制する皮膚疾患改善剤。
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