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公开(公告)号：WO2017099111A1
公开(公告)日：2017-06-15
申请号：PCT/JP2016/086337
申请日：2016-12-07
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , SHIMADA, Tsutomu , ANDO, Hirotake , KATO, Kazuhiko
CPC分类号： G02B21/26 , G02B21/24 , G02B21/244 , G02B21/365
摘要： A microscope system includes an observation optical system including an objective lens, an XY stage capable of moving an XY plane in an X-axis direction and an Y-axis direction, a first change unit configured to change a slant of the XY plane with respect to an optical axis direction of the objective lens, and a second change unit configured to change a slant of a slide placed on the XY stage with respect to the XY plane. Changing the slant of the XY plane by the first change unit is performed based on a first mark arranged on the XY plane at a position observable by the observation optical system. Changing the slant of the slide with respect to the XY plane by the second change unit is performed based on a second mark arranged on the slide.
摘要翻译： 显微镜系统包括：观察光学系统，其包括物镜; XY平台，其能够在X轴方向和Y轴方向上移动XY平面;第一改变单元，其被构造为改变 相对于物镜的光轴方向的XY平面的倾斜;以及第二改变单元，被配置为改变放置在XY平台上的载玻片相对于XY平面的倾斜。 基于在XY平面上布置在观察光学系统可观察的位置处的第一标记来执行由第一改变单元改变XY平面的倾斜。 基于设置在载玻片上的第二标记来执行通过第二改变单元改变载玻片相对于XY平面的倾斜。
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2.发明申请ADAPTER FOR MICROSCOPE SYSTEM AND MICROSCOPE SYSTEM INCLUDING THE ADAPTER 审中-公开适用于显微镜系统和包括适配器的显微镜系统
公开(公告)号：WO2016092813A1
公开(公告)日：2016-06-16
申请号：PCT/JP2015/006081
申请日：2015-12-08
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , NAGATSUKA, Osamu , NISHIKAWA, Koichiro
IPC分类号： G02B21/36
CPC分类号： G02B21/362
摘要： An adapter configured to connect a microscope and an imaging unit, comprises a first member connected to the microscope and a second member connected to the imaging unit. The adapter further comprises a positioning unit for determining the microscope and the imaging unit to a predetermined positional relationship at a first accuracy, and a driving mechanism that changes a positional relationship between the first member and the second member at a second accuracy higher than the first accuracy, thereby changing the positional relationship between the microscope and the imaging unit determined by the positioning unit.
摘要翻译： 配置为连接显微镜和成像单元的适配器包括连接到显微镜的第一构件和连接到成像单元的第二构件。 适配器还包括定位单元，用于以第一精度将显微镜和成像单元确定为预定的位置关系;以及驱动机构，其以比第一精度高的第二精度改变第一构件和第二构件之间的位置关系 从而改变由定位单元确定的显微镜与成像单元之间的位置关系。
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公开(公告)号：WO2017099100A1
公开(公告)日：2017-06-15
申请号：PCT/JP2016/086301
申请日：2016-12-07
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , SHIMADA, Tsutomu , SAKAI, Akihiro , KATO, Kazuhiko
CPC分类号： G02B21/34 , G02B21/241 , G02B21/26 , G02B27/40
摘要： A slide used for observation by a microscope includes a label area configured to arrange a label, a cover glass area configured to arrange an observation object and a cover glass, a position reference mark arranged in a vacant area between the label area and the cover glass area and configured to specify a reference position of the slide and an X-axis direction and a Y-axis direction that are orthogonal to each other, and focus reference marks in which a predetermined pattern is repetitively arranged along two opposing sides of four sides of a periphery of the cover glass area, the focus reference marks being configured to specify a Z-axis direction orthogonal to the X-axis direction and the Y-axis direction.
摘要翻译： 用于显微镜观察的载玻片包括被配置为布置标签的标签区域，被配置为布置观察对象和盖玻璃的盖玻璃区域，被布置在空白区域中的位置参考标记 在标签区域和盖玻片区域之间，并且被配置为指定滑块的基准位置和彼此正交的X轴方向和Y轴方向;以及焦点基准标记，其中预定图案被重复布置 沿着所述防护玻璃区域的周边的四个边中的两个相对侧，所述焦点基准标记被配置为指定与所述X轴方向和所述Y轴方向正交的Z轴方向。
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公开(公告)号：WO2016092818A1
公开(公告)日：2016-06-16
申请号：PCT/JP2015/006095
申请日：2015-12-08
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , HASEGAWA, Masahide , NAGATSUKA, Osamu , NISHIKAWA, Koichiro
CPC分类号： G02B21/26 , G02B21/365 , G02B21/367
摘要： A microscope system comprises a microscope body, a stage configured to place a slide as an observation target and move in an X direction and a Y direction. The microscope system changes an arrangement of the placed slide with respect to the stage so as to cause a direction indicated by a mark provided on the slide placed on the stage to align with one of the X direction and the Y direction of the stage.
摘要翻译： 显微镜系统包括显微镜主体，被配置为将幻灯片放置为观察目标并沿X方向和Y方向移动的台。 显微镜系统改变放置的滑块相对于舞台的布置，以便使得设置在放置在舞台上的滑块上的标记所指示的方向与舞台的X方向和Y方向之一对准。
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公开(公告)号：WO2016092815A2
公开(公告)日：2016-06-16
申请号：PCT/JP2015/006083
申请日：2015-12-08
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , HASEGAWA, Masahide , ANDO, Masahiro , NAGATSUKA, Osamu , NISHIKAWA, Koichiro
CPC分类号： G02B21/365 , G02B21/26 , G02B21/362
摘要： A microscope system comprises a microscope body, an image sensor mounted on the microscope body via mounting means and configured to capture an observation image under a microscope, and a stage that moves in an X-axis direction and a Y-axis direction, which are orthogonal to each other, and places a slide as an observation object and includes a mark used to indicate a stage reference position. The microscope system obtains positions of the stage in the X-axis direction and the Y-axis direction, and detects, from an image captured by the image sensor, the stage reference position indicated by a mark provided on the stage and a slide reference position indicated by a mark provided on a slide placed on the stage. The microscope system manages the position of the stage by coordinates based on the slide reference position if the slide reference position is detected, and manages the position of the stage by coordinates based on the stage reference position if the slide reference position is not detected.
摘要翻译： 显微镜系统包括：显微镜主体，通过安装装置安装在显微镜主体上并构造成在显微镜下拍摄观察图像的图像传感器，以及在X轴方向和Y轴方向上移动的台架 彼此正交，并且将幻灯片放置为观察对象，并且包括用于指示舞台参考位置的标记。 显微镜系统在X轴方向和Y轴方向上获得平台的位置，并且从由图像传感器拍摄的图像检测由设置在舞台上的标记指示的舞台基准位置和滑动参考位置 由放置在舞台上的幻灯片上提供的标记指示。 如果检测到滑动基准位置，则显微系统通过基于滑动基准位置的坐标来管理载物台的位置，并且如果未检测到滑动基准位置，则基于载物台基准位置来管理载物台的位置。
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公开(公告)号：WO2017099104A2
公开(公告)日：2017-06-15
申请号：PCT/JP2016/086318
申请日：2016-12-07
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , SAKAI, Akihiro , ANDO, Hirotake , KATO, Kazuhiko
CPC分类号： G02B21/367 , G02B21/24 , G02B21/244 , G02B21/26 , G02B21/365
摘要： A microscope system includes an observation optical system including an objective lens, an imaging unit configured to capture an image of an observation object obtained by the observation optical system, and a stage movable in an X-axis direction, a Y-axis direction, and a Z-axis direction, on which a slide of the observation object is placed. The microscope system obtains position information defined by the X-axis direction, the Y-axis direction, and the Z-axis direction, and stores the obtained position information and the image of the observation object obtained by capturing the observation object by the imaging unit in a storage in association with each other.
摘要翻译： 显微镜系统包括：观察光学系统，包括物镜;成像单元，被配置为拍摄由观察光学系统获得的观察对象的图像;以及平台，可沿X轴方向 ，Y轴方向和Z轴方向，观察对象的载玻片放置在其上。 显微镜系统获得由X轴方向，Y轴方向和Z轴方向限定的位置信息，并且将获得的位置信息和通过成像单元拍摄观察对象而获得的观察对象的图像进行存储 在相互关联的存储中。
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公开(公告)号：WO2016092820A1
公开(公告)日：2016-06-16
申请号：PCT/JP2015/006097
申请日：2015-12-08
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , HASEGAWA, Masahide , ANDO, Masahiro , NAGATSUKA, Osamu
CPC分类号： G02B21/26 , G01B5/004 , G02B21/245 , G02B21/362 , G02B27/32 , G02B27/60
摘要： A microscope system includes a microscope body, an XY stage mounted on the microscope body and including a stage configured to place a slide as an observation target and move in an X-axis direction and a Y-axis direction perpendicular to each other, and an XY two-dimensional scale plate fixed to the stage. The XY two-dimensional scale plate is provided with a first mark that provides axis information in the X-axis direction throughout a movable range of the stage in the Y-axis direction and a second mark that provides axis information in the Y-axis direction throughout a movable range of the stage in the X-axis direction, which are used to recognize X- and Y-coordinates of the stage.
摘要翻译： 显微镜系统包括：显微镜主体，安装在显微镜主体上的XY平台，并且包括将幻灯片放置为观察目标并且在彼此垂直的X轴方向和Y轴方向上移动的台架， XY二维刻度板固定在舞台上。 XY二维刻度板具有第一标记，该第一标记在Y轴方向上的台的可移动范围内沿X轴方向提供轴信息，以及第二标记，其在Y轴方向上提供轴信息 在X轴方向上的舞台的可移动范围内，用于识别舞台的X和Y坐标。
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公开(公告)号：WO2016092819A1
公开(公告)日：2016-06-16
申请号：PCT/JP2015/006096
申请日：2015-12-08
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , NISHIKAWA, Koichiro
CPC分类号： G02B21/34 , B01L3/508 , B01L3/54 , B01L2200/025 , B01L2300/021 , B01L2300/0822 , G02B27/32
摘要： A slide on which an observation object by a microscope is placed, is provided. A first mark indicating a reference line along a first direction and a second mark indicating a specific position on an extension of the reference line along the first direction are separately arranged in a vacant area between a label area used to arrange a label and a cover glass area used to arrange the observation object and a cover glass. A position reference is provided by the specific position on the extension of the reference line along the first direction.
摘要翻译： 提供了通过显微镜放置观察对象的幻灯片。 指示沿着第一方向的参考线的第一标记和指示沿着第一方向的参考线的延伸部上的特定位置的第二标记被分别布置在用于布置标签的标签区域和盖玻璃之间的空白区域中 用于安排观察对象的区域和盖玻璃。 通过沿着第一方向的参考线的延伸上的特定位置来提供位置参考。
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公开(公告)号：WO2016092812A1
公开(公告)日：2016-06-16
申请号：PCT/JP2015/006080
申请日：2015-12-08
发明人： SAKAMOTO, Michiie , HASHIGUCHI, Akinori , MASUDA, Shinobu , SAKATA, Tsuguhide , NAGATSUKA, Osamu , NISHIKAWA, Koichiro
CPC分类号： G02B21/367 , G02B21/241 , G02B21/26 , G02B21/361
摘要： A microscope system comprises a microscope body, an imaging unit connected to the microscope body and including an image sensor for capturing a microscopic image, and an XY stage configured to place a slide and move in an X direction and a Y direction. The microscope system changes an arrangement of the image sensor with respect to the microscope body so as to cause a direction defined by a pixel arrangement of the image sensor to align with one of the X direction and the Y direction of the XY stage.
摘要翻译： 显微镜系统包括显微镜主体，连接到显微镜主体的成像单元，并且包括用于捕获微观图像的图像传感器，以及XY台，其被配置为在X方向和Y方向上移动并移动。 显微镜系统改变图像传感器相对于显微镜主体的布置，以使得由图像传感器的像素排列限定的方向与XY平台的X方向和Y方向中的一个对准。
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