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公开(公告)号：WO2009148613A1
公开(公告)日：2009-12-10
申请号：PCT/US2009/003408
申请日：2009-06-04
发明人： DUFT, Bradford, J. , GREEN, Colin
CPC分类号： C12N15/1138 , C07K14/705 , C12N2310/11 , C12N2310/14
摘要： The present invention relates to delivery, including transdermal delivery, of a therapeutically effective amount of a compound useful for modulating gap junction formation and function, including an oligonucleotide for reducing gap junction formation and function, and methods and compositions for treating a subject suffering from pain associated with a disease, disorder or condition and associated with pain, including but not limited to muscle pain, ligament pain, tendon pain, joint pain and post-operative pain.
摘要翻译： 本发明涉及治疗有效量的用于调节间隙连接形成和功能的化合物的递送（包括透皮递送），包括用于减少间隙连接形成和功能的寡核苷酸，以及用于治疗患有疼痛的受试者的方法和组合物 与疾病，病症或病症相关并且与疼痛相关，包括但不限于肌肉疼痛，韧带疼痛，肌腱疼痛，关节疼痛和手术后疼痛。
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公开(公告)号：WO2007023307A1
公开(公告)日：2007-03-01
申请号：PCT/GB2006/003207
申请日：2006-08-25
IPC分类号： A61K31/352 , A61K39/395 , A61K31/517 , A61K31/5377 , A61P35/00
CPC分类号： A61K31/5377 , A61K31/352 , A61K31/517 , A61K39/395 , A61K39/39541 , A61K2300/00
摘要： The present invention relates to combinations of the xanthenone acetic acids class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and EGFR signalling pathway inhibitors. More particularly, the invention is concerned with the use of such combinations in the treatment of cancer and pharmaceutical compositions containing such combinations.
摘要翻译： 本发明涉及呫吨酮类乙酸类，例如5,6-二甲基呫吨酮-4-乙酸（DMXAA）和EGFR信号通路抑制剂的组合。 更具体地，本发明涉及这样的组合在治疗癌症中的用途以及含有这种组合的药物组合物。
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公开(公告)号：WO2011059760A2
公开(公告)日：2011-05-19
申请号：PCT/US2010/054543
申请日：2010-10-28
申请人： THE GREEN ELECTRIC COMPANY, A MASSACHUSETTS CORPORATION , LUCY, Dan , BLEVINS, Michael , GREEN, Colin , BLITTERSWYK, Nick
发明人： LUCY, Dan , BLEVINS, Michael , GREEN, Colin , BLITTERSWYK, Nick
CPC分类号： F03D3/0454 , F03D3/02 , F03D3/0409 , F03D3/0445 , F03D9/25 , F03D13/20 , F03D80/00 , F05B2240/13 , F05B2240/133 , F05B2240/40 , F05B2250/23 , Y02E10/74
摘要： Wind energy systems comprise a wind accelerator having a support assembly and an outer structure surrounding the support assembly. The wind accelerator has a front region and a rear region. The rear region is substantially wider than the front region, and the outer structure tapers from the rear region to the front region. One or more turbines are mounted on the support assembly at or near the rear region of the wind accelerator or at or near the widest point of the wind accelerator.
摘要翻译： 风能系统包括具有支撑组件和围绕支撑组件的外部结构的风力加速器。 风速加速器具有前部区域和后部区域。 后部区域比前部区域大得多，并且外部结构从后部区域向前部区域逐渐变细。 一个或多个涡轮机安装在风力加速器的后部区域处或附近的支撑组件上，或者在风力加速器的最宽点处或附近。
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公开(公告)号：WO2007023302A1
公开(公告)日：2007-03-01
申请号：PCT/GB2006/003196
申请日：2006-08-25
IPC分类号： A61K31/352 , A61K39/395 , A61K31/337 , A61P35/00
CPC分类号： A61K31/337 , A61K31/352 , A61K39/395 , A61K2300/00
摘要： The present invention relates to combinations of compounds such as compounds of the xanthenone acetic acid class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and vascular endothelial growth factor binders, in particular the monoclonal antibody Avastin TM (bevacizumab). More particularly, the invention is concerned with the use of such combinations in the treatment of cancer and pharmaceutical formulations containing such combinations.
摘要翻译： 本发明涉及诸如5,6-二甲基呫吨酮-4-乙酸（DMXAA）的呫吨酮乙酸类化合物和血管内皮生长因子结合剂的化合物的组合，特别是单克隆抗体Avastin TM， / SUP>（贝伐单抗）。 更具体地说，本发明涉及这样的组合在治疗癌症中的用途以及含有这种组合的药物制剂。
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