公开(公告)号：WO2015061800A3

公开(公告)日：2015-06-18

申请号：PCT/US2014062469

申请日：2014-10-27

Applicant: COLLINS SCOTT FORREST ,  BOLAND THOMAS ,  YANEZ MARIA

Inventor： COLLINS SCOTT FORREST ,  BOLAND THOMAS ,  YANEZ MARIA

IPC: A01N63/00 ,  A01N65/00 ,  A61K35/12

CPC classification number: A61L27/3839 ,  A61F2/12 ,  A61F2210/0076 ,  A61F2220/005 ,  A61F2240/004 ,  A61F2310/00371 ,  A61F2310/00377 ,  A61F2310/00383 ,  A61K35/28 ,  A61K35/33 ,  A61K35/35 ,  A61K35/44 ,  A61L27/225 ,  A61L27/227 ,  A61L27/3804 ,  A61L27/3808 ,  A61L27/3834 ,  A61L27/3886 ,  A61L27/52 ,  A61L2430/04 ,  C12N5/0653 ,  C12N5/0697 ,  C12N2502/1352 ,  C12N2502/28 ,  C12N2533/56 ,  C12N2533/76 ,  C12N2535/10 ,  A61K2300/00

Abstract: Tissue engineered constructs and methods for fabricating the disclosed constructs are provided. Some of the disclosed tissue engineered constructs are designed to fill a void in the body due to surgical resection, for example from mastectomy or lumpectomy, wounds and the like. Some disclosed constructs comprise one or more projections designed to mimic the appearance of a structural feature when implanted into a host.

Abstract translation: 提供了用于制造所公开的构建体的组织工程构建体和方法。 所公开的组织工程构建体中的一些被设计成由于手术切除，例如乳房切除术或乳房切除术，伤口等而填充身体中的空隙。 一些公开的结构包括一个或多个突出物，其被设计为当植入宿主时模拟结构特征的外观。

公开(公告)号：WO2004099107A3

公开(公告)日：2005-04-14

申请号：PCT/US2004001683

申请日：2004-01-22

Applicant: UNIV CLEMSON ,  BOLAND THOMAS ,  WAGNER THOMAS

Inventor： BOLAND THOMAS ,  WAGNER THOMAS

IPC: G01Q60/00 ,  C12Q1/68 ,  G06N3/12 ,  G11C11/54 ,  G11C13/02 ,  H01L27/10 ,  H01L35/24 ,  H01L49/00 ,  H01L51/30

CPC classification number: G06N3/123 ,  B82Y10/00 ,  G11C13/0014 ,  G11C13/0019 ,  H01L51/0093 ,  H01L51/0595 ,  Y10S977/946

Abstract: The present invention is directed to a memory device (120) having very high storage density capability. In general, the memory device (120) includes an array of individual memory cells (114) which store information that is assigned a value based on the molecular contents of the memory cell. In a preferred embodiment, the molecules utilized for storing information in the memory cells may be single-strand polynucleotides, for instance single-strand oligonucleotides (112) of between about 5 and about 20 monomer units. The present invention is also directed to methods and systems useful for writing and reading the molecular-based memory devices. In particular, the devices may be written and read via modified atomic force microscopy processes.

Abstract translation: 本发明涉及具有非常高的存储密度能力的存储器件（120）。 通常，存储器件（120）包括存储基于存储器单元的分子内容分配值的信息的单独存储器单元（114）的阵列。 在优选的实施方案中，用于将信息存储在记忆细胞中的分子可以是单链多核苷酸，例如约5至约20个单体单元的单链寡核苷酸（112）。 本发明还涉及用于写入和读取基于分子的存储器件的方法和系统。 特别地，可以通过经修改的原子力显微镜方法书写和读取装置。