公开(公告)号：WO2020249745A1

公开(公告)日：2020-12-17

申请号：PCT/EP2020/066328

申请日：2020-06-12

申请人： DANMARKS TEKNISKE UNIVERSITET

发明人： ANDRESEN, Thomas Lars ,  HENRIKSEN, Jonas Rosager ,  HANSEN, Anders Elias ,  BAK, Martin ,  JENSEN, Andreas Tue Ingemann ,  PETERSEN, Lars Ringgaard ,  JÆHGER, Ditte Elisabeth ,  MELANDER, Carl Frederik ,  ELIASEN, Rasmus ,  LARSEN, Jannik Bruun ,  HALLDÓTTIR, Hólmfridur Rósa

IPC分类号： A61K51/12 ,  A61K51/08 ,  A61K49/00 ,  A61K51/04 ,  C07K5/072 ,  C07K5/09 ,  C07K5/11 ,  G01N33/58

摘要： The present invention relates to cationic micelles, and in particular the compounds capable of forming such cationic micelles for use in cell tracking.

公开(公告)号：WO2021053163A1

公开(公告)日：2021-03-25

申请号：PCT/EP2020/076136

申请日：2020-09-18

申请人： DANMARKS TEKNISKE UNIVERSITET

发明人： HENRIKSEN, Jonas Rosager ,  ANDRESEN, Thomas Lars ,  JENSEN, Simon Skjøde ,  PARHAMIFAR, Ladan ,  MÜNTER DITHMAR, Rasmus ,  HANSEN, Anders Elias ,  STAVNSBJERG, Camilla ,  CHRISTENSEN, Esben

IPC分类号： A61K31/522 ,  A61K9/00 ,  A61K39/00 ,  A61K45/06 ,  A61N5/00 ,  A61P35/00

摘要： The present invention relates to immune stimulating micelle compositions, and their use in treatment of diseases and disorders, such as cancer. In particular, the present invention relates to micelle compositions comprising a TLR7 agonist, such as 1V270.

公开(公告)号：WO2019243422A1

公开(公告)日：2019-12-26

申请号：PCT/EP2019/066205

申请日：2019-06-19

申请人： DANMARKS TEKNISKE UNIVERSITET ,  NANOVI A/S

发明人： HENRIKSEN, Jonas Rosager ,  ANDRESEN, Thomas Lars ,  HANSEN, Anders Elias ,  JENSEN, Andreas Tue Ingemann ,  BRUUN, Linda Maria ,  JØLCK, Rasmus Irming

IPC分类号： A61K49/00 ,  A61K51/04 ,  A61K51/12

摘要： The present disclosure relates to a solution comprising a water insoluble carbohydrate and a fluorescent dye, such as a near infrared (NIR) contrast agent, wherein the solution sets under aqueous conditions, such as in vivo , to form e.g. a gel, a glass, a semi-solid, a solid, a crystal or any mixtures thereof. The disclosure further relates to preparation of such solution and use of such solution for in vivo imaging and/or guidance of surgery or interventional therapeutic procedures.

公开(公告)号：WO2019243419A1

公开(公告)日：2019-12-26

申请号：PCT/EP2019/066200

申请日：2019-06-19

申请人： DANMARKS TEKNISKE UNIVERSITET ,  NANOVI A/S

发明人： HENRIKSEN, Jonas Rosager ,  ANDRESEN, Thomas Lars ,  HANSEN, Anders Elias ,  JENSEN, Andreas Tue Ingemann ,  BRUUN, Linda Maria ,  ENGUDAR, Gokce ,  JØLCK, Rasmus Irming

IPC分类号： A61B90/00 ,  A61K9/00 ,  A61K51/12 ,  A61K51/04 ,  A61N5/10 ,  A61K47/26

摘要： The present disclosure relates to a solution comprising a water insoluble carbohydrate and a radionuclide chelated by a hydrophobic chelator, wherein the solution sets under aqueous conditions, such as in vivo , to form e.g. a gel, a semi-solid, a solid, a crystal or any mixtures thereof. The disclosure further relates to preparation of such solution and use of such solution for brachytherapy and/or guidance of surgery.