公开(公告)号：WO2019058226A1

公开(公告)日：2019-03-28

申请号：PCT/IB2018/057017

申请日：2018-09-13

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： BABA, Takashi ,  DZIEKONSKI, Eric Thomas

IPC: H01J49/42 ,  H01J49/00 ,  H01J49/28

Abstract: One or more ions are received along a central axis through a first set of reflectron plates of an ELIT. Voltages are applied to the first set of plates and to a second set of reflectron plates in order to trap and oscillate the one or more ions. A first induced current is measured from a cylindrical pickup electrode between the first set of reflectron plates and the second set of reflectron plates. A second induced current is measured from one or more plates of the first set of reflectron plates. A third induced current is measured from one or more plates of the second set of reflectron plates. The first measured induced current, second measured induced current and third measured induced current are combined to reduce higher order frequency harmonics of the induced current.

公开(公告)号：WO2022259201A1

公开(公告)日：2022-12-15

申请号：PCT/IB2022/055380

申请日：2022-06-09

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/42

Abstract: Systems and methods described herein provide for the injection of ions into an ELIT at a variety of kinetic energies such that the ions turn around at various locations. In certain aspects, such systems and methods for operating an ELIT may reduce ion density at the turning points to reduce the impact of the space charge effect. Various aspects of the present teachings also provide for the design or optimization of the ELIT electrode spacing and/or injection potentials to reduce the impact of the space charge effect. In some related aspects, the ELIT may additionally provide time-focusing of the various ion groups at the detector as they oscillate along their respective path lengths.

公开(公告)号：WO2022189924A1

公开(公告)日：2022-09-15

申请号：PCT/IB2022/051952

申请日：2022-03-04

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/06

Abstract: A mass spectrometer includes at least one ion guide having an inlet for receiving a plurality of ions from an upstream ion source and an outlet through which ions exit the ion guide, an ion routing device having an inlet for receiving at least a portion of the ions exiting the ion guide and at least two outlets, a first mass spectrometer positioned relative to the first outlet to receive ions exiting the ion routing device via the first outlet, and a second mass spectrometer positioned relative to the second outlet to receive ions exiting the ion routing device via the second outlet.

公开(公告)号：WO2022084764A1

公开(公告)日：2022-04-28

申请号：PCT/IB2021/058375

申请日：2021-09-14

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/42 ,  H01J49/06 ,  H01J49/00

Abstract: Systems and methods are disclosed for ion injection into an electrostatic trap. Various aspects of this disclosure provide a mass spectrometer system including a primary ion path including a plurality of quadrupoles; and a secondary ion path coupled to the primary ion path utilizing turning elements. The secondary ion path may include an electrostatic linear ion trap (ELIT), the ELIT being operable to analyze ions diverted from the primary ion path and return them to the primary ion path. The primary ion path may include a time-of-flight mass analyzer. The secondary ion path may be bi-directional. Ions may travel in a first direction when coupled into the secondary ion path using a first turning element in the primary ion path and may travel in a second direction when coupled into the secondary ion path utilizing a second turning element in the primary ion path. The secondary ion path may include a collision quadrupole.

公开(公告)号：WO2022079510A1

公开(公告)日：2022-04-21

申请号：PCT/IB2021/058383

申请日：2021-09-14

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/42

Abstract: Systems and methods are disclosed for ion injection into an electrostatic trap. As non-limiting examples, various aspects of this disclosure provide a quadrupole comprising first, second, and third quadrupole segments. The second quadrupole segment may be arranged between the first and third quadrupole segments and the first quadrupole segment and the third quadrupole segment may each comprise four poles with auxiliary electrodes arranged between each pair of the four poles. The second quadrupole segment may comprise four poles and the first and third quadrupoles each may comprise four individual auxiliary electrodes, two pairs of auxiliary electrodes,, two electrodes, or one pair of auxiliary electrodes. The auxiliary electrodes of the first quadrupole segment and the entrance lens may be biased at a same direct current (DC) voltage. The auxiliary electrodes of the third quadrupole segment and the exit lens may be biased at a same DC voltage.

公开(公告)号：WO2020121166A1

公开(公告)日：2020-06-18

申请号：PCT/IB2019/060573

申请日：2019-12-09

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/42

Abstract: An ELIT includes voltage sources (1101), switches (1102), a first set of electrode plates (1110) aligned along a central axis, and a second set of electrode plates (1120) aligned along the central axis with the first set. A first group of plates (310, 320; 810, 820) of the first set and the second set is positioned to trap ions within a first path length (340, 940). A second group of plates (410, 420) of the first set and the second set is positioned to trap ions within a shorter second path length (440, 1040). The switches select the first path length by applying voltages from the voltage sources to the first set and the second set that cause the first group of plates to trap ions within the first path length. Alternatively, the switches can select the second path length by applying voltages that cause the second group of plates to trap ions within the second path length.

公开(公告)号：WO2022180570A1

公开(公告)日：2022-09-01

申请号：PCT/IB2022/051644

申请日：2022-02-24

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/42 ,  H01J49/4245 ,  H01J49/4295

Abstract: Methods and systems for operating an ELIT are provided herein. In accordance with various aspects of the present teachings, and ELIT is provided that can enable simultaneous trapping of two different groups of ions as each group oscillates along a different path length within the ELIT.

公开(公告)号：WO2022168005A1

公开(公告)日：2022-08-11

申请号：PCT/IB2022/051008

申请日：2022-02-04

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/42

Abstract: In one aspect, a mass spectrometer is disclosed, which comprises an ion trap having a plurality of electrodes arranged in a multipole configuration so as to provide an inlet for receiving ions along a longitudinal axis into a space between the electrodes, where at least one of the plurality of electrodes comprises a passageway through which ions can be extracted radially from the ion trap. The electrodes are configured for application of one or more RF voltages thereto for providing radial confinement of the ions, and a DC voltage source configured to apply a dipolar DC voltage pulse across said at least one electrode and an opposed electrode for causing radial extraction of at least a portion of said ions from said ion trap through said passageway.

公开(公告)号：WO2022157641A1

公开(公告)日：2022-07-28

申请号：PCT/IB2022/050442

申请日：2022-01-19

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/02 ,  H01J49/40

Abstract: A Fourier Transform electrostatic linear ion trap (ELIT) is disclosed with an electron multiplier detector comprising one of a microchannel plate and a channel electron multiplier. An (ELIT) is provided comprising a central axis along which ions travel; an image current detector disposed at least partially around the central axis of the ELIT; and an electron multiplier detector arranged in an opening of the image current detector, the electron multiplier detector being operable to receive ions deflected from the central axis. The electron multiplier detector may have a front surface that is perpendicular to the central axis of the ELIT. The electron multiplier detector may comprise two separate elements at non-normal angles to the central axis of the ELIT. The image current detector may comprise a cylinder with the opening on one side in which the electron multiplier detector is arranged, a U-shape, or a half-tube detector.

公开(公告)号：WO2020121168A1

公开(公告)日：2020-06-18

申请号：PCT/IB2019/060575

申请日：2019-12-09

Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.

Inventor： DZIEKONSKI, Eric Thomas

IPC: H01J49/42

Abstract: An ion guide defining a guide axis receives ions. The ion guide applies a potential profile that includes a pseudopotential well to the ions using an ion control field. The ion control field includes a component for restraining movement of the ions normal to the guide axis and a component for controlling the movement of the ions parallel to the guide axis. The ion guide sequentially injects the ions with the same ion energy and in decreasing order of m/z value into an ELIT aligned along an ELIT axis to focus the ions irrespective of m/z value at the same location on the ELIT axis within the ELIT at the same time by varying a magnitude of the pseudopotential well. The ELIT can trap the focused ions using in-trap potential lift or mirror-switching ion capture.