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    NOVEL USE OF CARNOSIC ACID
    1.
    发明申请
    NOVEL USE OF CARNOSIC ACID 审中-公开

    公开(公告)号：WO2019185889A1

    公开(公告)日：2019-10-03

    申请号：PCT/EP2019/058053

    申请日：2019-03-29

    Applicant: DSM IP ASSETS B.V.

    Inventor： CLASADONTE, Laure ,  INDRASENA, Weerasinghe ,  NETSCHER, Thomas ,  WERHLI, Chistof

    IPC: A23K20/111 ,  A61K36/53

    Abstract: The present invention is directed towards the use of carnosic acid, preferably in combination with esters of ascorbic acid, as antioxidant, especially in feed for insects, aquatic and terrestrial animals and in feed ingredients such as fish meal, insect meal and poultry meal, as well as PUFA-containing oils such as marine oil, microbial oil, fungal oil, algal oil and PUFA-containing plant oil. The present invention is further directed towards feed ingredients and feed for insects, aquatic and terrestrial animals comprising carnosic acid, preferably in combination with esters of ascorbic acid.

    USE OF TWIN-CHROMANOLS AS ANTIOXIDANTS IN OIL
    4.
    发明申请
    USE OF TWIN-CHROMANOLS AS ANTIOXIDANTS IN OIL 审中-公开

    公开(公告)号：WO2019185939A1

    公开(公告)日：2019-10-03

    申请号：PCT/EP2019/058118

    申请日：2019-03-29

    Applicant: DSM IP ASSETS B.V.

    Inventor： CLASADONTE, Laure ,  DUESTERLOH, André ,  INDRASENA, Weerasinghe ,  NETSCHER, Thomas ,  STEMMLER, René, Tobias

    IPC: A23D9/00 ,  A23L3/3499 ,  A61K31/355 ,  A61P39/06

    Abstract: The present invention is directed towards the use of at least one compound of formula (I) wherein R 1 , R 2 and R 3 are independently from each other H or linear C 1-6- alkyl or branched C 3-8- alkyl, as antioxidant in PUFA-containing edible oils such as marine oil, microbial oil, fungal oil, algal oil and PUFA-containing plant oil for human consumption. The present invention is further directed towards these PUFA- containing edible oils comprising at least one compound of formula (I). The present invention is further directed to a method of preserving the shelf life of PUFAs and/or their esters in an edible oil comprising the step of adding at least one compound of formula (I) to said edible oil, as well as to a method of limiting the amount of oxidation of PUFAs and/or their esters in an edible oil which is exposed to air, comprising adding at least one compound of formula (I) to said edible oil, preferably in an amount of said compound of formula (I) ranging from 10 to 500 ppm, preferably ranging from 30 to 300 ppm, more preferably ranging from 100 to 250 ppm, based on the total amount of said edible oil.

    NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES
    5.
    发明申请
    NOVEL USE OF SUBSTITUTED 2H-CHROMENS AND THEIR DERIVATIVES 审中-公开

    公开(公告)号：WO2019185910A3

    公开(公告)日：2019-10-03

    申请号：PCT/EP2019/058081

    申请日：2019-03-29

    Applicant: DSM IP ASSETS B.V.

    Inventor： CLASADONTE, Laure ,  DUESTERLOH, André ,  INDRASENA, Weerasinghe ,  NETSCHER, Thomas ,  STEMMLER, René, Tobias ,  WERHLI, Chistof

    IPC: A23D9/007 ,  C07D311/70

    Abstract: The present invention is directed towards the use of 2 H -chromens and their derivatives of formula (I) and/or of formula (II) wherein R 1 and R 2 are independently from each other H or CM 1-11 -alkyl or (CH 2 ) n — OH with n being an integer from 1 to 6 or R 1 and R 2 together represent a keto group, and wherein R 3 , R 4 , R 5 , and R 6 are independently from each other H or C 1-6 -alkyl or C 1-6 -alkoxy, and R 7 is H or C 1-6 -alkyl, as antioxidants in PUFA-containing edible oils such as marine oil, microbial oil, fungal oil, algal oil and PUFA-containing plant oil for human consumption. The present invention is further directed towards these PUFA- containing edible oils comprising at least one compound of formula (I) and/or at least one compound of formula (II). The present invention is further directed to a method of preserving the shelf life of PUFAs and/or their esters in an edible oil comprising the step of adding at least one compound of formula (I) and/or at least one compound of formula (II) to said edible oil, as well as to a method of limiting the amount of oxidation of PUFAs and/or their esters in an edible oil which is exposed to air, comprising adding at least one compound of formula (I) and/or at least one compound of formula (II) to said edible oil, preferably in an amount of said compound of formula (I) and/or said compound of formula (II) ranging from 10 to 500 ppm, preferably ranging from 30 to 300 ppm, more preferably ranging from 100 to 250 ppm, based on the total amount of said edible oil.

    USE OF TOCOTRIENOLS AS ANTIOXIDANTS
    7.
    发明申请
    USE OF TOCOTRIENOLS AS ANTIOXIDANTS 审中-公开

    公开(公告)号：WO2019185942A1

    公开(公告)日：2019-10-03

    申请号：PCT/EP2019/058121

    申请日：2019-03-29

    Applicant: DSM IP ASSETS B.V.

    Inventor： CLASADONTE, Laure ,  INDRASENA, Weerasinghe ,  NETSCHER, Thomas

    IPC: A23D9/00 ,  A23L3/3499 ,  A61K31/355 ,  A61P39/06

    Abstract: The present invention is directed towards the use of at least one compound of formula (I) wherein R 1 , R 2 and R 3 are independently from each other H or C 1-4 -alkyl, as antioxidants, especially in feed such as pet food and feed ingredients such as fish meal, insect meal and poultry meal, as well as PUFA-containing oil such as marine oil, microbial oil, fungal oil, algal oil and PUFA-containing plant oil. The present invention is further directed towards feed ingredients and feed for insects, aquatic and terrestrial animals comprising such compounds of formula (I).

    NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS WITH EXTENDED LIPOPHILIC SIDE CHAINS
    8.
    发明申请
    NOVEL USE OF SUBSTITUTED CHROMAN-6-OLS WITH EXTENDED LIPOPHILIC SIDE CHAINS 审中-公开

    公开(公告)号：WO2019185941A1

    公开(公告)日：2019-10-03

    申请号：PCT/EP2019/058120

    申请日：2019-03-29

    Applicant: DSM IP ASSETS B.V.

    Inventor： CLASADONTE, Laure ,  DUESTERLOH, André ,  INDRASENA, Weerasinghe ,  NETSCHER, Thomas ,  STEMMLER, René, Tobias

    IPC: C07D311/72

    Abstract: The present invention is directed towards the use of substituted chroman-6-ols with extended lipophilic side chains of formula (I) wherein one of the two substituents R 1 and R 2 is C 12-21 -alkyl and the other of the two substituents R 1 and R 2 is either hydrogen or C 1-5 -alkyl or (CH 2 ) n -OH with n being an integer from 1 to 5, and wherein A is CH(R 3 ), and wherein R 3 , R 4 and R 6 are independently from each other H or C 1-4 -alkyl, and wherein R 5 is H or OH or C 1-4 -alkyl or C 1-4 -alkoxy; with the proviso that at least two of R 4 , R 5 and R 6 are not methyl, when R 3 is H, and one of the substituents R 1 and R 2 is methyl and the other of the two substituents R 1 and R 2 is C 12-21 -alkyl, as antioxidants in PUFA-containing edible oils such as marine oil, microbial oil, fungal oil, algal oil and PUFA-containing plant oil for human consumption. The present invention is further directed towards these PUFA containing edible oils comprising such substituted chroman-6-ols with extended lipophilic side chains of formula (I). The present invention is further directed to a method of preserving the shelf life of PUFAs and/or their esters in an edible oil comprising the step of adding at least one compound of formula (I) to said edible oil, as well as to a method of limiting the amount of oxidation of PUFAs and/or their esters in an edible oil which is exposed to air, comprising adding at least one compound of formula (I) to said edible oil, preferably in an amount of said compound of formula (I) ranging from 10 to 500 ppm, preferably ranging from 30 to 300 ppm, more preferably ranging from 100 to 250 ppm, based on the total amount of the edible oil.

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