公开(公告)号：WO2007056205A2

公开(公告)日：2007-05-18

申请号：PCT/US2006043077

申请日：2006-11-03

Applicant: EASTMAN CHEM CO

Inventor： SHELTON MICHAEL CHARLES ,  POSEY-DOWTY JESSICA DEE ,  EDGAR KEVIN JOSEPH ,  LINGERFELT LARRY RONNIE JR ,  KLEIN SANDRA ,  KIRK SHANE KIPLEY ,  DRESSMAN JENNIFER JOY

IPC: A61K9/14 ,  A61K47/38

CPC classification number: A61K9/141 ,  A61K9/10 ,  A61K31/717 ,  A61K47/38

Abstract: Disclosed herein are pharmaceutical compositions comprising carboxyalkylcellulose esters for delivery of pharmaceutically active substances having low solubility in a medium such as water, an acidic aqueous buffer, a neutral aqueous buffer, or a basic aqueous buffer. Also disclosed are methods for making pharmaceutical compositions and methods of administering the compositions.

Abstract translation: 本文公开了包含羧基烷基纤维素酯的药物组合物，用于递送在诸如水，酸性水性缓冲液，中性水性缓冲液或碱性水性缓冲液的介质中具有低溶解度的药学活性物质。 还公开了制备药物组合物的方法和施用组合物的方法。