公开(公告)号：WO2018053302A1

公开(公告)日：2018-03-22

申请号：PCT/US2017/051833

申请日：2017-09-15

Applicant: ENSEMBLE THERAPEUTICS CORPORATION

Inventor： BRIGGS, Timothy, F. ,  ALEXANDER, Sethu, L. ,  CIPRIANI, Tyler, J. ,  DAVIS, Heather ,  DUVALL, Jeremy, R. ,  HALE, Stephen P. ,  JIANG, Jun ,  LEE, Maurice, D., IV ,  MEHOVIC, Revonda, M. ,  MUNCIPINTO, Giovanni ,  OALMANN, Christopher, J. ,  SHORTSLEEVES, Kelley, C. ,  TERRETT, Nicholas, K.

IPC: C07D498/18 ,  C07D498/04 ,  A61K31/407 ,  A61K31/424 ,  A61P35/00

CPC classification number: C07D498/04 ,  A61K31/407 ,  A61K31/4245 ,  A61P35/00 ,  C07D498/18

Abstract: The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of indoleamine-2,3-dioxygenase (IDO) activity, and methods of treating IDO-related disorders.

Abstract translation: 本发明涉及用作吲哚胺-2,3-双加氧酶（IDO）活性拮抗剂的化合物及其药学上可接受的组合物，以及治疗IDO相关病症的方法。