公开(公告)号：WO2021250067A2

公开(公告)日：2021-12-16

申请号：PCT/EP2021/065403

申请日：2021-06-09

Applicant: FLAMMA SPA

Inventor： CHIESA, Francesco ,  VAHDATI, Leila ,  SCOTTI, Mario ,  COMI, Daniela ,  CREMONESI, Paolo ,  ARGESE, Maria ,  VERZINI, Massimo ,  HE, Wei

IPC: C07C269/08 ,  C07C271/12

Abstract: The present invention relates to a process for the purification of (R)-2-amino-3-phenylpropyl carbamate in perspective of the subsequent conversion in the corresponding HCl salt (SOLRIAMFETOL). The invention further relates to the process for preparing a batch of purified solriamfetol, as well as to the purified (R)-2-amino-3-phenylpropyl carbamate or its hydrochloride salt.