公开(公告)号：WO2011112144A1

公开(公告)日：2011-09-15

申请号：PCT/SE2011/050261

申请日：2011-03-10

Applicant: GE HEALTHCARE BIO-SCIENCES AB ,  SALOMONSSON, Daniel ,  BENNEMO, Petter ,  USELIUS, Per

Inventor： SALOMONSSON, Daniel ,  BENNEMO, Petter ,  USELIUS, Per

IPC: G01N30/60 ,  B01D15/22

CPC classification number: B01D15/22 ,  G01N30/6017 ,  G01N30/6026 ,  G01N30/603

Abstract: In a chromatography column, at least one plastic retaining mesh is attached to a distributor plate using a fixture element comprising an elongated edge that penetrates into the plastic mesh to ensure sealing and to prevent radial movement of the plastic mesh.

Abstract translation: 在色谱柱中，至少一个塑料保持网使用包括细长边缘的固定元件附接到分布板，所述细长边缘穿透塑料网以确保密封并防止塑料网的径向移动。

公开(公告)号：WO2020115165A2

公开(公告)日：2020-06-11

申请号：PCT/EP2019/083735

申请日：2019-12-04

Applicant: GE HEALTHCARE BIO-SCIENCES AB

Inventor： SALOMONSSON, Daniel ,  LUNDKVIST, Mats

IPC: B01D15/22 ,  G01N30/60 ,  B01D15/20

Abstract: Disclosed is a chromatographic separation column assembly (100) comprising a column cylinder (120) having a cylinder wall (126) including an inner wall surface (124) partially defining a column volume (50), and a column component (110/130) insertable into to the cylinder (120), wherein at least an edge region (113/133) of the column component is intended to be in contact or adjacent a part of the inner wall surface (124) in use, the edge region and the contacting or adjacent part of inner wall surface each being formed from a compatible heat fusible material or materials, and wherein at least the cylinder wall in the area of the contacting or adjacent part of the inner wall is formed from a material which allows transmission of the light energy needed to cause said fusing of the adapter plate edge region to the inner wall surface.

公开(公告)号：WO2011162678A1

公开(公告)日：2011-12-29

申请号：PCT/SE2011/050746

申请日：2011-06-16

Applicant: GE HEALTHCARE BIO-SCIENCES AB ,  RAMAKRISHNA, Manoj, Kumar ,  SALOMONSSON, Daniel ,  USELIUS, Per

Inventor： RAMAKRISHNA, Manoj, Kumar ,  SALOMONSSON, Daniel ,  USELIUS, Per

IPC: B01D15/10 ,  B01D15/22 ,  G01N30/60

CPC classification number: B01D15/10 ,  B01D15/22 ,  G01N30/56 ,  Y10T29/49721

Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).

Abstract translation: 一种用于在色谱柱（1; 41）上进行维护的方法，包括以下步骤：a）当需要维护时，将色谱柱的底板（5; 53）与可分离的接头（7; 63） （3; 43），其上提供色谱柱; b）将色谱系统中提供的适配器（15; 59）连接到色谱柱（1; 41）的任何部分，使得可以将底板（5; 53）从支架（3; 43） 适配器（15; 59）; 以及c）升高所述适配器（15; 59），从而也提升所述底板（5; 53），使得能够在所述底板（5; 53）下进行维护。

公开(公告)号：WO2018087339A1

公开(公告)日：2018-05-17

申请号：PCT/EP2017/078965

申请日：2017-11-10

Applicant: GE HEALTHCARE BIO-SCIENCES AB

Inventor： LUNDKVIST, Mats ,  SALOMONSSON, Daniel

IPC: B01D15/22 ,  G01N30/60

Abstract: Disclosed is a chromatography column cylinder (200) formed from a polymer composite comprising an outer layer (220) and inner layer (210) intended to be in direct contact with the intended contents of the cylinder in a volume (202), wherein the outer layer supports the inner layer, for example when there is negative pressure in the volume (202). In one embodiment, one of said layers is molded directly onto a surface of the other layer such that there is no gap between the two layers. Disclosed also is a method for forming a chromatography column cylinder.

Abstract translation: 公开了一种由聚合物复合材料形成的色谱柱圆柱体（200），所述聚合物复合材料包括外层（220）和内层（​​210），所述外层（220）和内层（​​210）旨在直接接触圆柱体的预期内容物 体积（202），其中例如当体积（202）中存在负压时，外层支撑内层。 在一个实施例中，所述层之一被直接模制到另一层的表面上，使得两层之间不存在间隙。 还公开了一种形成色谱柱筒的方法。

公开(公告)号：WO2011152788A1

公开(公告)日：2011-12-08

申请号：PCT/SE2011/050681

申请日：2011-06-01

Applicant: GE HEALTHCARE BIO-SCIENCES AB ,  GEBAUER, Klaus ,  RAMAKRISHNA, Manoj, Kumar ,  SALOMONSSON, Daniel ,  USELIUS, Per

Inventor： GEBAUER, Klaus ,  RAMAKRISHNA, Manoj, Kumar ,  SALOMONSSON, Daniel ,  USELIUS, Per

IPC: G01N30/60 ,  B01D15/22

CPC classification number: B01D15/22 ,  B01D15/1864 ,  B01D15/1885 ,  F16L55/00 ,  G01N30/461 ,  G01N30/466 ,  G01N30/6004 ,  Y10T29/49826

Abstract: A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.

Abstract translation: 连接在刚性壳体（21; 61）中的色谱柱模块（3a，b，c; 13a，b，c; 53a，b，c，90a，b）的平行组件（2; 11; 51） 具有一个共同的组装入口（15; 55）和一个公共组件出口（17; 57），每个柱模块包括填充有色谱介质的床空间（29），并且每个柱模块包括集成流体导管，当柱模块连接时 其中在刚性壳体中的其它柱模块适于将柱模块的床空间（29）与组件入口（15; 55）和组件出口（17; 57）连接，其中总长度和/ 从组装入口到一个床空间的流体导管以及从同一床空间到组件出口的流体导管的长度和/或体积与安装在平行组件中的所有床空间和模块基本相同。