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    OPTICAL FLOW CELL
    1.
    发明申请
    OPTICAL FLOW CELL 审中-公开

    公开(公告)号：WO2019229201A1

    公开(公告)日：2019-12-05

    申请号：PCT/EP2019/064119

    申请日：2019-05-29

    Applicant: GE HEALTHCARE BIO-SCIENCES AB

    Inventor： EHRING, Hanno ,  LUNDKVIST, Mats ,  BERGMAN, David ,  MARCSTRÖM, Andreas

    IPC: G01N21/05 ,  G01N21/03

    Abstract: Disclosed is an optical flow cell (300') comprising: a housing (910) forming;an enclosed and elongated fluid channel (920) arranged along a first axis (923);a first light guide (961) and a second light guide (962) generally concentrically arranged along a second axis (970) and on opposite side walls of the fluid channel, said first and second light guides having ends (961c,962c) removed in situ to provide a sensing gap (d).

    AN ATTACHMENT ARRANGEMENT FOR A COLUMN HOLDER
    2.
    发明申请
    AN ATTACHMENT ARRANGEMENT FOR A COLUMN HOLDER 审中-公开
    一个支架的附件安排

    公开(公告)号：WO2010126433A1

    公开(公告)日：2010-11-04

    申请号：PCT/SE2010/050454

    申请日：2010-04-23

    Applicant: GE HEALTHCARE BIO-SCIENCES AB ,  LUNDKVIST, Mats

    Inventor： LUNDKVIST, Mats

    IPC: G01N30/60 ,  B01L9/00 ,  F16B2/22 ,  F16B13/00

    CPC classification number: B01L9/50 ,  F16B2/243 ,  F16B2/245 ,  F16B21/09 ,  G01N30/6047

    Abstract: An attachment arrangement comprising -two resilient arms (1a, 1b) connected to a device to be attached, the other ends of the resilient arms (1a, 1b) pointing away from each other; -one locking part (7a, 7b) on each resilient arm (1a, 1b), said locking parts (7a, 7b) being T- shaped and adapted to together fit into a T-groove by forcing the resilient arms (1a, 1b) towards each other and twist the attachment arrangement during insertion into the T-groove. Said attachment arrangement is secured in the T-groove when the attachment arrangement is twisted back again and the pressure on the resilient arms (1a, 1b) is released. A column holder provided with an attachment arrangement according to the invention.

    Abstract translation: 一种连接装置，包括： - 连接到待连接装置的两个弹性臂（1a，1b），弹性臂（1a，1b）的另一端彼此指向; （1a，1b）上的一个锁定部分（7a，7b），所述锁定部分（7a，7b）是T形并且一体地通过迫使弹性臂（1a，1b）配合到T形槽中 ）朝向彼此并且在插入T形槽期间扭转附接装置。 当附接装置再次扭转并且弹性臂（1a，1b）上的压力被释放时，所述附接装置固定在T形槽中。 一种柱保持器，其具有根据本发明的附接装置。

    CHROMATOGRAPHY COLUMN
    3.
    发明申请
    CHROMATOGRAPHY COLUMN 审中-公开
    色谱柱

    公开(公告)号：WO2018087339A1

    公开(公告)日：2018-05-17

    申请号：PCT/EP2017/078965

    申请日：2017-11-10

    Applicant: GE HEALTHCARE BIO-SCIENCES AB

    Inventor： LUNDKVIST, Mats ,  SALOMONSSON, Daniel

    IPC: B01D15/22 ,  G01N30/60

    Abstract: Disclosed is a chromatography column cylinder (200) formed from a polymer composite comprising an outer layer (220) and inner layer (210) intended to be in direct contact with the intended contents of the cylinder in a volume (202), wherein the outer layer supports the inner layer, for example when there is negative pressure in the volume (202). In one embodiment, one of said layers is molded directly onto a surface of the other layer such that there is no gap between the two layers. Disclosed also is a method for forming a chromatography column cylinder.

    Abstract translation: 公开了一种由聚合物复合材料形成的色谱柱圆柱体（200），所述聚合物复合材料包括外层（220）和内层（​​210），所述外层（220）和内层（​​210）旨在直接接触圆柱体的预期内容物 体积（202），其中例如当体积（202）中存在负压时，外层支撑内层。 在一个实施例中，所述层之一被直接模制到另一层的表面上，使得两层之间不存在间隙。 还公开了一种形成色谱柱筒的方法。

    LIQUID FRACTION COLLECTOR FOR LIQUID CHROMATOGRAPHY SYSTEM
    4.
    发明申请
    LIQUID FRACTION COLLECTOR FOR LIQUID CHROMATOGRAPHY SYSTEM 审中-公开
    液相色谱系统用液体馏分收集器

    公开(公告)号：WO2017129802A1

    公开(公告)日：2017-08-03

    申请号：PCT/EP2017/051867

    申请日：2017-01-27

    Applicant: GE HEALTHCARE BIO-SCIENCES AB

    Inventor： DARGY, Stefan ,  BJERNULF, Olle ,  LUNDKVIST, Mats

    IPC: G01N30/80 ,  G01N35/02 ,  G01N35/04

    CPC classification number: G01N30/80 ,  G01N35/1011

    Abstract: Disclosed is a fraction collector for dispensing liquids into plural receptacles (P1,P2) arranged in a two dimensional array. The fraction collector comprises a table (22) for supporting said receptacles, and an arm supported above the table, in turn supporting a liquid dispenser (35), the fraction collector arm is rotatable about an arm axis (C) and the liquid dispenser is movable along the arm on a carriage 34 (Figure 2). Thereby, the dispenser is low cost and is repositionable simply above the receptacles as a result of said rotation and as a result of said movement along the arm, without occupying too much laboratory bench space.

    Abstract translation: 公开了一种用于将液体分配成布置成二维阵列的多个容器（P1，P2）的分部收集器。 所述馏分收集器包括用于支撑所述接收器的桌子（22）和支撑在所述桌子上方的臂，所述臂又支撑液体分配器（35），所述馏分收集器臂可绕臂轴线（C）旋转，并且所述液体分配器 可沿支架34上的臂移动（图2）。 因此，分配器成本低，并且由于所述旋转和作为所述沿着臂的运动的结果，可简单地重新定位在容器上方，而不会占用太多的实验室工作台空间。

    CHROMATOGRAPHY COLUMN AND METHOD OF ASSEMBLING THE SAME
    6.
    发明申请
    CHROMATOGRAPHY COLUMN AND METHOD OF ASSEMBLING THE SAME 审中-公开

    公开(公告)号：WO2020115165A2

    公开(公告)日：2020-06-11

    申请号：PCT/EP2019/083735

    申请日：2019-12-04

    Applicant: GE HEALTHCARE BIO-SCIENCES AB

    Inventor： SALOMONSSON, Daniel ,  LUNDKVIST, Mats

    IPC: B01D15/22 ,  G01N30/60 ,  B01D15/20

    Abstract: Disclosed is a chromatographic separation column assembly (100) comprising a column cylinder (120) having a cylinder wall (126) including an inner wall surface (124) partially defining a column volume (50), and a column component (110/130) insertable into to the cylinder (120), wherein at least an edge region (113/133) of the column component is intended to be in contact or adjacent a part of the inner wall surface (124) in use, the edge region and the contacting or adjacent part of inner wall surface each being formed from a compatible heat fusible material or materials, and wherein at least the cylinder wall in the area of the contacting or adjacent part of the inner wall is formed from a material which allows transmission of the light energy needed to cause said fusing of the adapter plate edge region to the inner wall surface.

    OPTICAL FLOW CELL
    7.
    发明申请
    OPTICAL FLOW CELL 审中-公开

    公开(公告)号：WO2018100032A1

    公开(公告)日：2018-06-07

    申请号：PCT/EP2017/080916

    申请日：2017-11-30

    Applicant: GE HEALTHCARE BIO-SCIENCES AB

    Inventor： EHRING, Hanno ,  LUNDKVIST, Mats ,  BERGMAN, David, Carl, Martin ,  MARCSTROM, Andreas

    IPC: G01N21/03 ,  G01N21/05

    Abstract: The invention relates to an optical flow cell comprising a housing forming an enclosed and elongated fluid channel arranged along a first axis, an inlet arranged to connect a first outer surface area of the housing to a first end of the fluid channel and an outlet arranged to connect a second outer surface area to a second end of the fluid channel, a first light guide and a second light guide concentrically arranged along a second axis and on opposite side walls of the fluid channel. The invention further relates to a corresponding method to produce an optical flow cell.

    FLUID SAMPLE HOLDERS WITH PISTON VALVE
    8.
    发明申请
    FLUID SAMPLE HOLDERS WITH PISTON VALVE 审中-公开
    带活塞阀的流体样品瓶

    公开(公告)号：WO2013014193A1

    公开(公告)日：2013-01-31

    申请号：PCT/EP2012/064610

    申请日：2012-07-25

    Applicant: GE HEALTHCARE BIO-SCIENCES AB ,  LUNDKVIST, Mats

    Inventor： LUNDKVIST, Mats

    IPC: B01L3/02 ,  G01N35/10

    CPC classification number: G01N1/28 ,  B01L3/0217 ,  B01L3/502715 ,  B01L3/52 ,  B01L2300/123 ,  B01L2400/0478 ,  B01L2400/0487 ,  B01L2400/065 ,  G01N35/1097

    Abstract: Disclosed is a fluid sample holder 20 for delivering or receiving a fluid sample to or from fluid processing equipment such as a chromatography column 5 (Figure 1). The sample holder 20 comprises: a sample fluid reservoir 15; a sample fluid port 23; a buffer fluid port 21; and a sliding seal 25 within the reservoir 15 having an external area 258 (Figure 3) which generally sealing engages with a wall of the reservoir 15 thereby defining first 22 and second 24 fluid separated regions in the reservoir 15. The sliding seal 25 is displaceable within the reservoir 15 by means of a working fluid pressure differential between the first 22 and second 24 regions to thereby change the respective volumes of the first and second regions, and the external area at least is formed from a plastics moulded material which elastically flexes when subjected to a pressure differential greater than the working fluid pressure differential and when so flexed allows fluid flow between the first and second regions.

    Abstract translation: 公开了一种流体样品保持器20，用于将流体样品递送或接收到流体处理设备例如色谱柱5（图1）。 样品保持器20包括：样品流体储存器15; 样品流体端口23; 缓冲液口21; 和储存器15内的滑动密封件25具有外部区域258（图3），该外部区域通常密封地与贮存器15的壁接合，由此限定储存器15中的第一22和第二24个流体分离区域。滑动密封件25可移位 在储存器15内通过第一和第二区域24之间的工作流体压力差，从而改变第一和第二区域的相应体积，并且外部区域至少由塑料模制材料形成，该塑料模制材料弹性弯曲时 受到大于工作流体压力差的压差，并且当其弯曲时允许流体在第一和第二区域之间流动。

    MIXING DEVICE
    9.
    发明申请
    MIXING DEVICE 审中-公开

    公开(公告)号：WO2020089250A1

    公开(公告)日：2020-05-07

    申请号：PCT/EP2019/079567

    申请日：2019-10-29

    Applicant: GE HEALTHCARE BIO-SCIENCES AB

    Inventor： LUNDKVIST, Mats

    IPC: B01F3/08 ,  B01F5/06

    Abstract: The present disclosure relates to a mixing device (9) comprising an inlet channel (25), an outlet channel (27), a mixing cavity (29) and a laminar mixing element (31) arranged within the mixing cavity. The inlet channel extends along an axis (21) of the mixing device from a first end (23) of the mixing device to the mixing cavity. The outlet channel extends along the axis from the mixing cavity to a second end (24) of the mixing device arranged opposite to the first end. The mixing cavity is arranged between the inlet channel and the outlet channel and extends in an axial direction (A) along the axis and in a radial direction (R) outwardly from the axis to an outer wall (30) of the mixing cavity. The laminar mixing element extends radially across the mixing cavity, subdividing the mixing cavity into an inlet portion (26) and an outlet portion (28). The mixing element comprises a plurality of holes (41) extending through the mixing element. The said holes are distributed over the mixing element.

    CHROMATOGRAPHY SYSTEM AND COUPLINGS THEREFOR
    10.
    发明申请
    CHROMATOGRAPHY SYSTEM AND COUPLINGS THEREFOR 审中-公开

    公开(公告)号：WO2019002515A1

    公开(公告)日：2019-01-03

    申请号：PCT/EP2018/067498

    申请日：2018-06-28

    Applicant: GE HEALTHCARE BIO-SCIENCES AB

    Inventor： LUNDKVIST, Mats ,  JOHANSSON, Bjorn, A. ,  FRANCOIS, Tim

    IPC: F16L33/22 ,  F16L37/56 ,  F16L37/138

    Abstract: Disclosed are chromatography systems employing a releasable coupling (100) for holding a fluid tubing to a spigot, the coupling comprising: a cylindrical inner component (110) for accepting a fluid tubing (30), said inner component including a resiliently deflectable portion (118) arranged to urge an outer surface of the tubing toward a spigot; and a cylindrical collar (130) having and internal through-aperture (132) for slideably accepting the inner component, the aperture and resilient portion having complementary surface formations which in a first position of the collar mounted to the inner component provide for said resilient deflection in use, and which in a second different position do not cause said deflection, the coupling being characterized in that the collar comprises a collar flange (134) extending outwardly away from the aperture of a size allowing manual manipulation of the collar between the first and second positions. Chromatography systems employing said couplings is disclosed also.

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