公开(公告)号：WO2021224679A1

公开(公告)日：2021-11-11

申请号：PCT/IB2021/000303

申请日：2021-05-05

Applicant: GENOFOCUS, INC.

Inventor： PAN, Jae Gu ,  KIM, Eui Joong ,  KIM, Jeong Hyun ,  YUM, Do Young

IPC: A61K38/44 ,  A61K35/742 ,  A61P43/00 ,  A61P27/02 ,  C12N9/02 ,  A61K39/00

Abstract: The present invention relates, in part, to methods of preventing or treating macular degeneration in a subject by co-administering a superoxide dismutase enzyme and probiotic Bacillus sp. spores, especially a Bacillus amyloliquefaciens GF423 or GF424 mutant strain. The present invention also provides pharmaceutical and/or food compositions comprising a superoxide dismutase enzyme and probiotic Bacillus sp. spores.

公开(公告)号：WO2018164468A1

公开(公告)日：2018-09-13

申请号：PCT/KR2018/002677

申请日：2018-03-07

Applicant: GENOFOCUS, INC.

Inventor： YUM, Do Young ,  KIM, Jeong Hyun ,  PAN, Jae Gu ,  KIM, Eui Joong ,  YANG, Taek Ho ,  KANG, Ji Eun ,  PARK, Soo Young ,  KIM, Hyun Do

IPC: A61K38/16 ,  A23L33/18 ,  A23K20/142 ,  A23K10/16 ,  A61K8/64 ,  A61Q19/00 ,  A23K10/10 ,  A23K20/195

Abstract: The present invention relates to a Bacillus amyloliquefaciens strain that produces superoxide dismutase (SOD), and also relates to an antioxidant, anti-inflammatory pharmaceutical composition and a pharmaceutical composition and food composition for preventing or treating hyperlipidemia, which include a superoxide dismutase produced by the Bacillus amyloliquefaciens strain. The compositions of the present invention exhibit excellent effects without causing side effects, and may thus be used as functional raw materials or products having an enhanced activity of preventing or treating inflammation, cancer or hyperlipidemia in the pharmaceutical drug, food, cosmetic and livestock fields.