公开(公告)号：WO2022246155A1

公开(公告)日：2022-11-24

申请号：PCT/US2022/030191

申请日：2022-05-20

Applicant: GLEGHORN, Jason, P. ,  MODI, Saurabh ,  SHIRAZI, Jasmine

Inventor： GLEGHORN, Jason, P. ,  MODI, Saurabh ,  SHIRAZI, Jasmine

IPC: G01N33/543 ,  G01N33/552 ,  G01N27/447 ,  C12M1/34

Abstract: The present invention provides a method for quantifying moving heterologous nanoparticles in a suspension by imaging. The quantifying method comprises acquiring at least one z-stack of images within the suspension; tracking the nanoparticles in the images to identify unique nanoparticles; and enumerating the unique nanoparticles. Also provided is a method for characterizing size distribution of moving heterologous nanoparticles in a suspension by imaging. The characterization method comprises acquiring time lapse images; tracking the nanoparticles in the images to identify unique nanoparticles; determining the locations of each of the unique particles; determining the size of each of the unique nanoparticles; and aggregating the sizes of the unique nanoparticles.