公开(公告)号：WO2015195660A1

公开(公告)日：2015-12-23

申请号：PCT/US2015/036025

申请日：2015-06-16

申请人： HEARTWARE, INC.

发明人： ANDRUS, Lance Lynn ,  CASTILLO, Andre

IPC分类号： A61M1/10

CPC分类号： A61M1/1008 ,  A61M1/101 ,  A61M1/122

摘要： In one embodiment, the present invention includes a connector ring assembly 220 to attach a VAD to a heart. The assembly 220 includes a clamp 224 which can rotate completely about the annular wall 222 in a first state and is fixed relative to the annular wall 222 in a second state. The clamp 224 transitions from the first state to the second state via an actuator 234. The actuator 234 can be configured with an axis of rotation 138 generally parallel to the opening 50 of the annular wall 222, thereby allowing manipulation of the actuator 234 through the same surgical accessway as that used to implant the connector ring assembly 220. At least one embodiment provides a connector flange 172 separately from an annular wall 122 to provide greater access to the connector flange 172 during implantation. The annular wall 122 and clamp 124 are attached to the connector flange 172 after the flange is fixed to the heart.

摘要翻译： 在一个实施例中，本发明包括将VAD连接到心脏的连接器环组件220。 组件220包括夹具224，夹具224可在第一状态下围绕环形壁222完全旋转，并且在第二状态下相对于环形壁222固定。 夹具224经由致动器234从第一状态转变到第二状态。致动器234可以被构造成大致平行于环形壁222的开口50的旋转轴138，从而允许致动器234通过 与用于植入连接器环组件220的手术入口相同的外科入口。至少一个实施例提供了与环形壁122分开的连接器凸缘172，以在植入期间提供对连接器凸缘172的更大的通路。 在凸缘固定到心脏之后，环形壁122和夹具124附接到连接器凸缘172。

公开(公告)号：WO2015192076A1

公开(公告)日：2015-12-17

申请号：PCT/US2015/035657

申请日：2015-06-12

申请人： HEARTWARE, INC.

发明人： ANDRUS, Lance Lynn ,  CASTILLO, Andre

IPC分类号： A61M39/02 ,  A61M1/12 ,  A61B5/00 ,  H01R13/52 ,  H01R13/62

CPC分类号： H01R13/6205 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/122 ,  A61M1/127 ,  A61M39/0247 ,  A61M2039/0267 ,  A61M2039/0288 ,  A61M2205/3507 ,  A61M2205/3515 ,  H01R13/2421 ,  H01R13/5224

摘要： In one embodiment, the present invention includes a percutaneous skin connector 1 including a base 3 and a cap 2. The base 3 has a channel 31 extending through it and a plurality of base magnets 24, 29 are positioned around the channel 31 and exposed at a base surface 30. A skirt 21 which allows tissue ingrowth extends from the base 3 to further secure the base 3 to the patient. The connector 1 also includes a cap 2 with a bore 61 extending through it and a plurality of cap magnets 47, 48 positioned around the bore 61 and exposed at a cap surface 42. The base magnets 24, 29 and cap magnets 47, 48 attract and align the cap surface 42 to the base surface 30. The connector 1 further includes a release mechanism adapted to at least partially separate the cap 2 from the base 3 when the cap 2 is rotated relative to the base 3 and out of alignment with the base 3.

摘要翻译： 在一个实施例中，本发明包括一个包括基座3和盖子2的皮肤皮肤连接器1.基座3具有延伸通过它的通道31，并且多个基本磁体24,29围绕通道31定位并暴露在 基部表面30.允许组织向内生长的裙部21从基部3延伸以进一步将基部3固定到患者身上。 连接器1还包括具有延伸穿过其的孔61的盖2和围绕孔61定位并暴露在盖表面42处的多个帽磁体47,48。基底磁体24,29和帽磁体47,48吸引 并且将盖表面42对准基底表面30.连接器1还包括释放机构，该释放机构适于在帽2相对于底座3旋转并且不与第二基座3对准时至少部分地将盖2与基座3分开 基地3。

公开(公告)号：WO2017117361A1

公开(公告)日：2017-07-06

申请号：PCT/US2016/069136

申请日：2016-12-29

申请人： HEARTWARE, INC.

发明人： ANDRUS, Lance Lynn

IPC分类号： A61M1/10 ,  A61M1/12

CPC分类号： A61B17/3423 ,  A61B2017/3425 ,  A61M1/1008 ,  A61M1/122

摘要： A mounting structure for connecting a device to an organ. The mounting structure includes a mounting element defining a bore. The mounting element is adapted for mounting to an exterior surface of the organ of a living subject. The mounting element includes a collar having a deformable wall defining a main bore. A gimbal ring disposed within the main bore and within the collar is included, the gimbal ring defining a gimbal bore co-axial with the main bore and including a plurality of separate arcuate elements cooperatively disposed in a circumferential direction around the gimbal bore, the plurality of separate arcuate elements being movable toward one another to constrict the gimbal bore.

摘要翻译：

用于将装置连接到器官的安装结构。 安装结构包括限定孔的安装元件。 安装元件适于安装到活体的器官的外表面。 安装元件包括具有限定主孔的可变形壁的轴环。 包括设置在主孔内和套环内的万向节环，万向节环限定与主孔同轴的万向节孔并且包括多个分离的弓形元件，弓形元件在围绕万向节孔的圆周方向上配合地设置，多个 单独的弧形元件可以相互移动以收缩万向节孔。

公开(公告)号：WO2017172738A1

公开(公告)日：2017-10-05

申请号：PCT/US2017/024501

申请日：2017-03-28

申请人： HEARTWARE, INC.

发明人： LAROSE, Jeffrey A. ,  ANDRUS, Lance Lynn

IPC分类号： A61M1/10

CPC分类号： A61M1/1008 ,  A61B17/02 ,  A61B2017/0243

摘要： An apparatus for protecting heart tissue from an implanted inlet element of a blood pump. The apparatus includes a flange member having a first radially constricted configuration and a second radially expanded configuration, the flange member being biased in its second radially expanded configuration. The flange member defines an opening there through sized to receiving the inlet element of the blood pump. A retaining element extending from the flange member is included, the retaining element being flexible and sized to be disposed about at least a portion of the inlet element.

摘要翻译： 用于保护心脏组织免受血泵的植入式入口元件的装置。 该设备包括具有第一径向收缩构型和第二径向扩张构型的凸缘构件，该凸缘构件被偏置成其第二径向扩张构型。 该法兰构件限定了一个开口，其大小适合接纳血泵的入口元件。 包括从凸缘构件延伸的保持元件，保持元件是柔性的并且尺寸设置为围绕入口元件的至少一部分设置。

公开(公告)号：WO2017106673A2

公开(公告)日：2017-06-22

申请号：PCT/US2016/067219

申请日：2016-12-16

申请人： HEARTWARE, INC.

发明人： ANDRUS, Lance Lynn

IPC分类号： A61M1/10

CPC分类号： A61M1/1008 ,  A61B17/320016 ,  A61B2017/00247 ,  A61B2017/320052 ,  A61F2/2409 ,  A61F2/2427 ,  A61M1/1098 ,  A61M1/122 ,  A61M2039/244 ,  A61M2210/125

摘要： A mounting element defining a bore, the mounting element being configured to mount to an exterior surface of an organ of a patient. A one way valve sized to be received and retained within the bore of the mounting element is included, the one way valve having an open position and a closed position. The one way valve substantially occludes the bore when the valve is in the closed position. The one way valve is biased in the closed position. A plug having a lumen extending there through is included, the plug being configured to be releasably inserted through at least a portion of the one way valve. The plug is configured to transition the one way valve from the closed position to the open position and to maintain the one way valve in the open position when the plug is inserted within the bore.

摘要翻译： 限定孔的安装元件，安装元件构造成安装到患者的器官的外表面。 包括单向阀，该单向阀的尺寸被容纳并保持在安装元件的孔内，单向阀具有打开位置和关闭位置。 当阀处于关闭位置时，单向阀基本上堵塞孔。 单向阀偏置在关闭位置。 包括具有延伸穿过其中的内腔的塞子，塞子被构造成可释放地插入穿过单向阀的至少一部分。 该插头被构造成当插头插入孔内时将单向阀从关闭位置转换到打开位置并且将单向阀保持在打开位置。

公开(公告)号：WO2015061314A4

公开(公告)日：2015-04-30

申请号：PCT/US2014/061575

申请日：2014-10-21

申请人： HEARTWARE, INC.

发明人： ANDRUS, Lance Lynn

IPC分类号： A61M1/10 ,  A61B17/04 ,  A61B17/34

摘要： A mounting ring for a ventricular assist device or other device used in the heart includes a plate 10 adapted to be secured to the exterior of the heart by rigid anchors such as hook 61, pin 173, or screw 181. When hooks 61 are used, they can be pivotally mounted to the plate 10 so that the hooks 61 can rotate from retracted positions to advanced positions. A tool 70 can be included in a mounting ring kit to move the hooks 61 from their retracted positions to their advanced positions so that the hooks 61 secure the plate 10 to the heart. Preferably, all of the hooks 61 are advanced simultaneously. The VAD or other device is then secured to the plate 10. The plate 10 can be mounted to the heart in less time than required to install a traditional mounting ring by suturing to the heart.