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    PRESSURE SENSING VENTRICULAR ASSIST DEVICES AND METHODS OF USE
    1.
    发明申请
    PRESSURE SENSING VENTRICULAR ASSIST DEVICES AND METHODS OF USE 审中-公开

    公开(公告)号：WO2018183568A1

    公开(公告)日：2018-10-04

    申请号：PCT/US2018/024947

    申请日：2018-03-28

    申请人： TC1 LLC

    发明人： HARJES, Daniel I. ,  FREDERICK, Kathryn B. ,  LEE, Eric

    IPC分类号： A61M1/10

    CPC分类号： A61M1/1086 ,  A61B5/0031 ,  A61B5/02405 ,  A61B5/029 ,  A61M1/1036 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/3334 ,  A61M2205/3507 ,  A61M2210/125

    摘要： The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.

    METHOD AND OPHTHALMIC DEVICE WITH ACTIVE AGENT RELEASE SYSTEM
    2.
    发明申请
    METHOD AND OPHTHALMIC DEVICE WITH ACTIVE AGENT RELEASE SYSTEM 审中-公开
    具有活性剂释放系统的方法和眼科装置

    公开(公告)号：WO2015164563A1

    公开(公告)日：2015-10-29

    申请号：PCT/US2015/027216

    申请日：2015-04-23

    申请人： JOHNSON & JOHNSON VISION CARE, INC.

    发明人： PUGH, Randall B ,  MARTIN, W. Anthony ,  SNOOK, Sharika

    IPC分类号： A61F9/00

    CPC分类号： A61F9/0017 ,  A61F2250/0002 ,  A61F2250/0068 ,  A61M31/002 ,  A61M2205/3507 ,  A61M2205/3538 ,  A61M2205/3584 ,  A61M2205/50

    摘要： The present invention provides an energized ophthalmic device (150) with an active agent release system (105) and an associated method. The active agent release system can be suitable to dispense an active agent including, for example, a vitamin, lubricant, a saline, a solvent, and/or medicament, at one or more predetermined times, through the use of an energization element (100) contained in the ophthalmic device. The energization element may be a battery and/or an energy receptor antenna. The release of the active agent can be according to a signal received wirelessly, a predetermined time, and/or a sensed condition, which can cause an activation element to conduct a current to at least a portion of a metal cap under stress causing it to fold and thereby expose the active agent to a surrounding environment.

    摘要翻译： 本发明提供具有活性剂释放系统（105）和相关方法的通电眼科装置（150）。 活性剂释放系统可以适于在一个或多个预定时间通过使用通电元件（100）来分配包括例如维生素，润滑剂，盐水，溶剂和/或药物的活性剂 ）包含在眼科装置中。 通电元件可以是电池和/或能量接收器天线。 活性剂的释放可以根据无线接收的信号，预定时间和/或感测条件，这些信号可以导致激活元件在应力下将金属帽的至少一部分传导到金属帽的一部分， 从而将活性剂暴露于周围环境。

    IMPELLER POSITION COMPENSATION USING FIELD ORIENTED CONTROL
    5.
    发明申请
    IMPELLER POSITION COMPENSATION USING FIELD ORIENTED CONTROL 审中-公开
    使用面向对象的控制装置的叶轮位置补偿

    公开(公告)号：WO2014116676A1

    公开(公告)日：2014-07-31

    申请号：PCT/US2014/012511

    申请日：2014-01-22

    申请人： THORATEC CORPORATION

    发明人： YANAI, Masamichi ,  CAMPAU, Jeffrey ,  NANNA, Jason C.

    IPC分类号： A61M1/12

    CPC分类号： F04D15/0094 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1031 ,  A61M1/1036 ,  A61M1/1086 ,  A61M1/122 ,  A61M2205/3303 ,  A61M2205/3507 ,  F04B35/04 ,  F04D7/04 ,  F04D13/024 ,  F04D13/0666 ,  F04D15/0088 ,  F04D29/041 ,  F04D29/0473 ,  F04D29/048 ,  F04D29/22 ,  F04D29/426 ,  F04D29/428 ,  H02P6/18

    摘要： A centrifugal pump system having an impeller rotating with first and second magnetic structures on opposite surfaces. A levitation magnetic structure is disposed at a ftrst end of a pump housing having a levitating magnetic field for axially attracting the first magnetic structure. A multiphase magnetic stator at a second end of the pump housing generates a rotating magnetic field for axially and rotationally attracting the second magnetic structure. A commutator circuit provides a plurality of phase voltages to the stator. A sensing circuit determines respective phase currents. A controller calculates successive commanded values for the phase voltages in response to the determined phase currents and a variable commutation angle. The angle is selected to correspond to an axial attractive force of the stator that maintains a levitation of the impeller at a centered position within the pumping chamber.

    摘要翻译： 一种离心泵系统，其具有在相对表面上以第一和第二磁性结构旋转的叶轮。 悬浮磁性结构设置在具有用于轴向吸引第一磁性结构的悬浮磁场的泵壳体的最前端。 在泵壳的第二端处的多相磁性定子产生用于轴向和旋转地吸引第二磁性结构的旋转磁场。 换向器电路向定子提供多个相电压。 感测电路确定各自的相电流。 控制器响应于所确定的相电流和可变换流角来计算相电压的连续命令值。 角度被选择为对应于定子的轴向吸引力，其保持叶轮在泵送室内的中心位置的悬浮。

    CONTROLLER AND POWER SOURCE FOR IMPLANTABLE BLOOD PUMP
    8.
    发明申请
    CONTROLLER AND POWER SOURCE FOR IMPLANTABLE BLOOD PUMP 审中-公开
    可植入血液泵的控制器和电源

    公开(公告)号：WO2012078873A1

    公开(公告)日：2012-06-14

    申请号：PCT/US2011/063949

    申请日：2011-12-08

    申请人： HEARTWARE, INC. ,  RUDSER, John ,  LAROSE, Jeffrey, A.

    发明人： RUDSER, John ,  LAROSE, Jeffrey, A.

    IPC分类号： A61M1/10

    CPC分类号： A61M1/1001 ,  A61M1/101 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/127 ,  A61M2205/17 ,  A61M2205/18 ,  A61M2205/3507 ,  A61M2205/3569 ,  A61M2205/502 ,  A61M2205/6018 ,  A61M2205/8206

    摘要： Methods and apparatus for controlling the operation of, and providing power for and to, implantable ventricular assist devices which includes a pump employing a brushless DC motor-driven blood pump, are disclosed. In one embodiment, a control system for driving an implantable blood pump is provided. The digital processor is responsive to data associated with the operation of the pump received at the data transfer pump, and from program data stored in the memory, (i) to determine therefrom, the identity of the pump, (ii) to determine therefrom, electrical characteristics and features of the identified pump, and (iii) to adaptively generate and apply to the data port, control signals for driving the identified pump.

    摘要翻译： 公开了用于控制植入式心室辅助装置的操作和为其提供动力的方法和装置，其包括采用无刷直流电动机驱动的血泵的泵。 在一个实施例中，提供了一种用于驱动可植入血液泵的控制系统。 数字处理器响应于在数据传输泵处接收到的泵的操作与从存储在存储器中的程序数据相关联的数据，（i）从其确定泵的身份，（ii）从其确定， 所识别的泵的电气特征和特征，以及（iii）自适应地生成并应用到数据端口，用于驱动识别的泵的控制信号。

    SYSTEM FOR CONTROLLED ADMINISTRATION OF A SUBSTANCE FROM A HUMAN-BODY-IMPLANTED INFUSION DEVICE
    9.
    发明申请
    SYSTEM FOR CONTROLLED ADMINISTRATION OF A SUBSTANCE FROM A HUMAN-BODY-IMPLANTED INFUSION DEVICE 审中-公开
    用于人体植入式输注装置的物质的受控管理系统

    公开(公告)号：WO2012011132A1

    公开(公告)日：2012-01-26

    申请号：PCT/IT2010/000319

    申请日：2010-07-20

    申请人： SCUOLA SUPERIORE Dl STUDI UNIVERSITARI E Dl PERFEZIONAMENTO SANT'ANNA ,  RICOTTI, Leonardo ,  ASSAF, Tareq ,  STEFANINI, Cesare ,  MENCIASSI, Arianna

    发明人： RICOTTI, Leonardo ,  ASSAF, Tareq ,  STEFANINI, Cesare ,  MENCIASSI, Arianna

    IPC分类号： A61M5/142 ,  A61M5/172 ,  A61M39/04

    CPC分类号： A61M5/1723 ,  A61M5/14276 ,  A61M39/04 ,  A61M2205/3507 ,  A61M2205/502 ,  A61M2205/8206 ,  A61M2209/045 ,  A61M2209/086

    摘要： A system for the controlled administration of a substance by means of an infusion device implanted in the human body comprising an implantable unit (200) for detecting a shortage or an excess of such substance or a physiological parameter correlatable to the shortage or excess of such substance, an infusion group of this substance (100) implantable in the peritoneal cavity and comprising a central control unit (105) for processing data received from the detection unit (200) in order to generate command signals for the release of the substance in the intraperitoneal cavity, energy storage means (106) to power said infusion group (100). The system also comprises a carrier of said substance (500) adapted to be ingested in order to passively reach the duodenal lumen, made of perforable material resistant to gastric acids and with parts in magnetizable metal, and a refilling device (103) for refilling the infusion group (100) with said substance, comprising a magnetic reversible docking group (113) for said carrier (500), facing the duodenal lumen and actuable when said carrier reaches a predetermined distance therefrom, and means (120) for drawing the substance from said carrier communicating with suction means (110) of said infusion group (100).

    摘要翻译： 用于通过植入人体内的输注装置对物质进行受控管理的系统，包括用于检测短缺或过量的这种物质的可植入单元（200）或与该物质的短缺或过量相关的生理参数 ，该植入物体（100）的输注组，其可植入腹腔内，并包括用于处理从检测单元（200）接收的数据的中央控制单元（105），以产生用于释放腹膜内物质的指令信号 空腔，能量存储装置（106）以对所述输注组（100）供电。 该系统还包括适于摄取的所述物质（500）的载体，以便被动地到达十二指肠腔，由抗胃酸的可穿透材料和可磁化金属中的部分制成，以及用于再填充 具有所述物质的输注组（100），包括用于所述载体（500）的磁性可逆对接组（113），面向十二指肠腔并且当所述载体到达预定距离时可致动，以及用于将物质从 所述载体与所述输注组（100）的抽吸装置（110）通信。

    STIMULATION OF PENIS ERECTION
    10.
    发明申请
    STIMULATION OF PENIS ERECTION 审中-公开
    刺激的影响

    公开(公告)号：WO2010040555A2

    公开(公告)日：2010-04-15

    申请号：PCT/EP2009/007288

    申请日：2009-10-09

    申请人： MILUX HOLDING SA ,  FORSELL, Peter

    发明人： FORSELL, Peter

    IPC分类号： A61F2/26

    CPC分类号： A61M5/14276 ,  A61F2/26 ,  A61F5/41 ,  A61M5/158 ,  A61M5/1723 ,  A61M2005/14284 ,  A61M2202/0007 ,  A61M2205/0216 ,  A61M2205/04 ,  A61M2205/10 ,  A61M2205/3303 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3379 ,  A61M2205/3507 ,  A61M2205/3523 ,  A61M2205/353 ,  A61M2205/3606 ,  A61M2205/50 ,  A61M2205/8206 ,  A61M2210/167 ,  A61M2230/005 ,  A61M2230/08 ,  A61M2230/30

    摘要： A penis erection stimulation system comprises a fully implantable drug delivery device for delivering a drug in relation to a penis to achieve erection of the penis. The drug delivery device may comprise a catheter adapted to be implanted in the corpora cavernosa of a penis or in close proximity thereto in order to deliver drugs through said catheter. Alternatively, one or more infusion needles may be disposed within and implanted along with one or more housings adjacent the patient's left and right corpora cavernosa. A reservoir and a pump may also be implanted inside the patient's body to supply the infusion needle with infusion liquid. A drive unit also adapted for implantation inside the patient's body is arranged for advancing and retracting the tip end of the infusion needle such that it penetrates the housing at least in two different penetration areas either simultaneously or in immediate time succession, thereby injecting drugs along with the infusion liquid into the patient's body for stimulating penis erection.

    摘要翻译： 阴茎勃起刺激系统包括用于递送与阴茎相关的药物以实现阴茎勃起的完全可植入的药物递送装置。 药物输送装置可以包括导管，其适于植入阴茎的阴茎海绵体中或与其非常接近，以便通过所述导管输送药物。 或者，一个或多个输注针可以设置在邻近患者的左侧和右侧海绵体的一个或多个外壳内并与之一起植入。 也可以将储存器和泵植入患者体内以向输液针供应输注液体。 还适于植入患者体内的驱动单元布置成用于推进和缩回输注针的末端，使得其至少在两个不同的穿透区域中同时或立即连续地穿透壳体，从而将药物与 将输液送入患者体内刺激阴茎勃起。