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公开(公告)号：WO2016191790A1
公开(公告)日：2016-12-08
申请号：PCT/AU2015/050294
申请日：2015-05-29
申请人： HEXIMA LIMITED
IPC分类号： C07K14/415 , A61P31/00 , A61P17/08 , A61K38/16
CPC分类号： A61K38/168 , A61K38/1729 , A61K38/55 , A61K45/06 , A61L27/54 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/25 , A61L2300/252 , A61L2300/404 , A61L2300/434 , A61P31/04 , A61P31/10 , C07K14/415 , A61K2300/00
摘要： The present disclosure teaches the treatment or prophylaxis of infection by a microorganism including a fungus or bacterium which is infecting or colonizing an in vivo tissue, surface or membrane. The method comprising administering to the subject with the infection or directly to the site of infection a plant-derived defensin or a functional variant or derivative thereof.
摘要翻译： 本公开教导了治疗或预防感染的微生物，包括感染或定植体内组织，表面或膜的真菌或细菌。 该方法包括向受试者施用感染或直接向感染部位施用植物来源的防御素或其功能变体或衍生物。
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公开(公告)号：WO2016061619A1
公开(公告)日：2016-04-28
申请号：PCT/AU2015/050293
申请日：2015-05-29
申请人： HEXIMA LIMITED
CPC分类号： A61K38/168 , A61K9/0014 , A61K31/137 , A61K31/4174 , A61K31/4196 , A61K31/4418 , A61K31/454 , A61K31/496 , A61K31/5375 , A61K31/69 , A61K45/06 , A61K2300/00
摘要： The present disclosure relates to the control of fungal infection of horn-like envelopes covering dorsal and terminal phalanges in humans and animals and related cerebral protrusions in animals as well as keratin comprising material on surfaces of humans and animals. Agents and natural and synthetic formulations and extracts useful for the control of fungal infection of these envelopes and related protrusions and keratin comprising material are also encompassed by the subject disclosure. In an embodiment, the present disclosure teaches the treatment of fungal infection of nails and in particular onychomycosis in humans.
摘要翻译： 本公开内容涉及在人和动物中覆盖背部和末端趾骨以及包括人和动物表面上的材料的角蛋白的角状包膜的真菌感染的控制。 用于控制这些信封和相关突起和包含角蛋白的材料的真菌感染的药剂和天然和合成制剂和提取物也包括在本发明的内容中。 在一个实施方案中，本公开教导了治疗指甲的真菌感染，特别是人的甲真菌病。
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