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    WATER DISINTEGRABLE FLUSHABLE CATHETER WITH A HYDROPHILIC COATING
    2.
    发明申请
    WATER DISINTEGRABLE FLUSHABLE CATHETER WITH A HYDROPHILIC COATING 审中-公开
    具有水解涂层的防水消毒导管

    公开(公告)号：WO2015089181A2

    公开(公告)日：2015-06-18

    申请号：PCT/US2014/069534

    申请日：2014-12-10

    申请人： HOLLISTER INCORPORATED

    发明人： CLARKE, John, T. ,  MONTES DE OCA BALDERAS, Horacio ,  ROSTAMI, Shamsedin

    IPC分类号： A61M25/00

    CPC分类号： A61L29/085 ,  A61L29/043 ,  A61L29/14 ,  A61L29/148 ,  A61L2400/10 ,  A61L2420/08 ,  A61M25/002 ,  A61M25/0043 ,  A61M25/0045 ,  A61M25/0082 ,  A61M25/0097 ,  C08L67/04 ,  C08L39/06

    摘要： This is a water disintegrable, flushable catheter that will dissolve or biodegrade in water. It is coated with a hydrophilic coating and will achieve lubricity values typical of a hydrophilic catheter. The catheter may be formed of a bi-layer tube that has a biodegradable outer layer such as polylactic acid and a purely water disintegrable inner layer, e.g., polyvinyl alcohol (PVOH). The outer layer will support the hydrophilic coating even when it's wetted and thus acts as a stable primer layer for hydrophilic style coatings. The outer layer bonds well to the water disintegrable inner layer but also allows a hydrophilic coating to be applied on top. The outer layer acts as a temporary water barrier. This water barrier allows the hydrophilic coating to be hydrated prior to use but prevents water molecules from attacking the PVOH inner layer. Alternatively, a hydrophilic coating that bonds to either the tubing directly or a via a primer layer but unlike typical hydrophilic coatings the coating is pre- activated by organic activation agents other than water and thus the catheter does not break down in the packaging or sterilization

    摘要翻译： 这是一种水分解，可冲洗的导管，将在水中溶解或生物降解。 它涂覆有亲水涂层，并且将实现亲水导管的典型的润滑性值。 导管可以由双层管形成，该双层管具有可生物降解的外层，例如聚乳酸和纯水崩解内层，例如聚乙烯醇（PVOH）。 外层即使在润湿时也能支撑亲水性涂层，因此作为亲水性涂层的稳定底漆层。 外层与水可分解的内层良好地结合，但也可以在顶部施加亲水涂层。 外层作为临时防水屏障。 该水屏障允许亲水涂层在使用前水合，但防止水分子攻击PVOH内层。 或者，亲水涂层直接或通过底漆层连接到管道上，但与典型的亲水涂层不同，涂层由水以外的有机活化剂预活化，因此导管在包装或灭菌中不会分解

    SELECTIVELY WATER DISINTEGRABLE MATERIALS AND CATHETERS MADE OF SUCH MATERIALS
    5.
    发明申请
    SELECTIVELY WATER DISINTEGRABLE MATERIALS AND CATHETERS MADE OF SUCH MATERIALS 审中-公开
    这些材料的选择性水质消毒材料和导管

    公开(公告)号：WO2016205383A1

    公开(公告)日：2016-12-22

    申请号：PCT/US2016/037650

    申请日：2016-06-15

    申请人： HOLLISTER INCORPORATED

    发明人： CLARKE, John, T. ,  MONTES DE OCA BALDERAS, Horacio

    IPC分类号： A61L29/04 ,  A61L29/08 ,  A61L29/14

    CPC分类号： A61L29/049 ,  A61L29/085 ,  A61L29/141 ,  A61L2420/06 ,  C08L29/04

    摘要： Polymeric materials that are blends of polymers having differing water solubility rates are disclosed. The blends may be incorporated into at least a portion of a medical devices such as the shafts of flushable urinary catheters to provide suitable catheter stiffness/flexibility and catheter disintegration in water receptacles such as toilets. The blended material may provide the substrate of the catheter shaft or may provide one or more layers of the catheter

    摘要翻译： 公开了具有不同水溶性速率的聚合物共混物的聚合材料。 混合物可以并入医疗装置的至少一部分，例如可冲洗的导尿管的轴，以在诸如厕所的水容器中提供合适的导管刚度/柔性和导管分解。 混合材料可以提供导管轴的基底，或者可以提供一层或多层导管

    A METHOD AND APPARATUS FOR MOLDING AN ELONGATED HOLLOW ARTICLE
    9.
    发明申请
    A METHOD AND APPARATUS FOR MOLDING AN ELONGATED HOLLOW ARTICLE 审中-公开
    一种用于模制延长中空文章的方法和装置

    公开(公告)号：WO2017039992A1

    公开(公告)日：2017-03-09

    申请号：PCT/US2016/046387

    申请日：2016-08-10

    申请人： HOLLISTER INCORPORATED

    发明人： MONTES DE OCA BALDERAS, Horacio ,  EICHLER, Herbert ,  STEINER, Gottfried ,  MARCH, Daniel, A. ,  MARCHETTI, Gilberto

    IPC分类号： B29C45/17 ,  B29C45/26 ,  B29C45/56 ,  B29L31/00 ,  B29L23/00

    CPC分类号： B29C45/1703 ,  B29C45/1705 ,  B29C45/261 ,  B29C45/56 ,  B29C2045/5695 ,  B29L2023/00 ,  B29L2031/7542

    摘要： A molding apparatus includes a mold comprising a stationary outer mold with a substantially tubular mold cavity, a moveable end mold with an end mold cavity alignable with the tubular mold cavity, and a stationary elongated mold core with a fluid channel therethrough, the mold core extending through the tubular cavity into the end mold cavity. A method of using the apparatus includes injecting a molding material at a material flow rate into the mold, moving the end mold at a speed in a linear direction from a first position to a second position, supplying a fluid at a fluid flow rate to the fluid channel, and varying at least one of the material flow rate, the end mold speed and the fluid flow rate as the end mold moves from the first position to the second position.

    摘要翻译： 模制装置包括模具，其包括具有基本上管状的模腔的固定外模，具有可与管状模腔对准的端模空腔的可移动端模以及具有穿过其的流体通道的固定细长模芯，模芯延伸 通过管状空腔进入端模腔。 使用该装置的方法包括以材料流速将模塑材料注入模具中，以从第一位置到第二位置的线性方向的速度移动端模，将流体流速提供给 流体通道，并且随着端模从第一位置移动到第二位置，改变材料流速，端模速度和流体流速中的至少一个。