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    ADHESION LAYER BONDED TO AN ACTIVATED SURFACE
    1.
    发明申请
    ADHESION LAYER BONDED TO AN ACTIVATED SURFACE 审中-公开

    公开(公告)号：WO2019108730A1

    公开(公告)日：2019-06-06

    申请号：PCT/US2018/062958

    申请日：2018-11-29

    Applicant: THE TRUSTEES OF PRINCETON UNIVERSITY

    Inventor： SCHWARTZ, Jeffrey ,  LIM, Kelly

    IPC: H01L21/00 ,  H01L21/30

    CPC classification number: A61L27/042 ,  A61L27/18 ,  A61L27/306 ,  A61L27/3633 ,  A61L27/3804 ,  A61L27/54 ,  A61L2400/18 ,  A61L2420/06 ,  A61L2420/08 ,  C08L83/04

    Abstract: A method is disclosed for coating surfaces that are unreactive or of low reactivity toward an inorganic alkoxide, in order to modify surface properties. The surface is activated by oxidation or amination to produce reactive functionality on the surface, followed by chemical reaction with an inorganic alkoxide to form an inorganic adhesion layer on the surface. This adhesion layer transforms the surface into one that reacts readily with a phosphonic acid that can then be used to impart hydrophobic or cell-adhesive properties to the surface or that can be transformed to attach bioactive substrates through metal-catalyzed coupling procedures. The adhesion layer can serve to bond directly with other organics that are reactive toward such metal oxides. Also disclosed are coated surfaces and constructs comprising the coated surfaces.

    DRUG ELUTING FOAMS AND THE PRODUCTION THEREOF
    7.
    发明申请
    DRUG ELUTING FOAMS AND THE PRODUCTION THEREOF 审中-公开
    药物治疗药物及其生产

    公开(公告)号：WO2016137327A1

    公开(公告)日：2016-09-01

    申请号：PCT/NL2016/050142

    申请日：2016-02-29

    Applicant: POLYGANICS IP B.V.

    Inventor： TOOREN, Martin Franke ,  RIBBELS, Romke Stephan Rudolf

    IPC: A61L27/54 ,  A61L27/56 ,  A61L27/58

    CPC classification number: A61L27/56 ,  A61L27/18 ,  A61L27/54 ,  A61L27/58 ,  A61L2420/08

    Abstract: The invention is directed to a multilayered drug eluting biodegradable foam comprising at least two layers, wherein each layer independently comprises a polymer and wherein at least one of said layers is a drug-comprising layer, which comprises at least one drug that is mixed with the polymer in said drug-comprising layer.

    Abstract translation: 本发明涉及一种包含至少两层的可生物降解泡沫的多层药物，其中每层独立地包含聚合物，并且其中至少一个所述层是药物包含层，其包含至少一种与 所述药物包含层中的聚合物。

    MULTI-LAYER ADHESIVE TAPE TO COMPRESS AND CONTRACT A SCAR
    8.
    发明申请
    MULTI-LAYER ADHESIVE TAPE TO COMPRESS AND CONTRACT A SCAR 审中-公开
    多层粘合带压缩和合同一个SCAR

    公开(公告)号：WO2016107897A1

    公开(公告)日：2016-07-07

    申请号：PCT/EP2015/081404

    申请日：2015-12-30

    Applicant: MACTAC EUROPE SPRL

    Inventor： BOELEN, Audrey ,  BARBIEUX, Régis

    IPC: A61L15/58 ,  A61L15/40

    CPC classification number: A61L15/58 ,  A61F13/0243 ,  A61F13/0253 ,  A61F13/0259 ,  A61L15/225 ,  A61L15/42 ,  A61L2420/08

    Abstract: The current invention concerns a multi-layer adhesive tape to compress and contract one or more scars, comprising: ‒ a top layer (4); ‒ a bonding layer (3) adjacent to said top layer (4); ‒ a bottom layer (2) adjacent to said bonding layer (3) and opposite to said top layer (4); ‒ an adhesive layer (1) adjacent to said flexible bottom layer (2) and opposite to said bonding layer (3); and ‒ a first peelable liner (7) at least adjacent to said adhesive layer (1) and opposite to said bottom layer (2), wherein the widths (L') of said top layer (4) and bonding layer (3) are larger than the widths (L) of said bottom layer (2) and adhesive layer (1), and wherein said adhesive layer (1) comprises a rubber-or acrylic-based pressure-sensitive adhesive. The invention further concerns a multi-layer adhesive tape to compress and contract one or more scars, wherein said top layer (4) has a thickness between 20 and 1100 µm.

    Abstract translation: 本发明涉及一种用于压缩和收缩一个或多个疤痕的多层胶带，包括：顶层（4）; - 与所述顶层（4）相邻的接合层（3）; - 邻近所述粘合层（3）并与所述顶层（4）相对的底层（2）。 - 与所述柔性底层（2）相邻并与所述粘合层（3）相对的粘合层（1）; 和 - 至少与所述粘合剂层（1）相邻并且与所述底层（2）相对的第一可剥离衬垫（7），其中所述顶层（4）和粘结层（3）的宽度（L'）为 大于所述底层（2）和粘合剂层（1）的宽度（L），并且其中所述粘合剂层（1）包括橡胶或丙烯酸类压敏粘合剂。 本发明还涉及一种用于压缩和收缩一个或多个疤痕的多层胶带，其中所述顶层（4）具有在20和1100μm之间的厚度。

    PROCESS FOR FORMING A THERMALLY AND CHEMICALLY INERT MULTILAYER FILM
    9.
    发明申请
    PROCESS FOR FORMING A THERMALLY AND CHEMICALLY INERT MULTILAYER FILM 审中-公开
    形成一个热和化学反应多层膜的方法

    公开(公告)号：WO2016083456A1

    公开(公告)日：2016-06-02

    申请号：PCT/EP2015/077655

    申请日：2015-11-25

    Applicant: SWISS MEDICAL COATINGS SARL

    Inventor： BALIC, Edin

    IPC: A61L27/30 ,  A61L27/34 ,  A61L27/50 ,  A61L31/08 ,  A61L31/10 ,  A61L31/14

    CPC classification number: A61L27/306 ,  A61L27/34 ,  A61L27/50 ,  A61L31/088 ,  A61L31/10 ,  A61L31/14 ,  A61L2420/02 ,  A61L2420/08 ,  C08L27/18

    Abstract: A process for forming a thermally and chemically inert multi-layer film on a substrate, comprising depositing a composition comprising one or more inorganic oxide material, or mixtures thereof, on the substrate such as to form a continuous layer comprising a at least partially fused inorganic oxide material; depositing a composition comprising one or more non-fluorinated silane compounds, or mixtures thereof, on the continuous layer comprising a fused inorganic oxide material such as to form a layer comprising non-fluorinated polysiloxane; depositing a composition comprising one or more fluorinated silane compounds on the layer comprising non-fluorinated polysiloxane such as to form a layer comprising fluorinated silanes bearing a fluorinated group; depositing a composition comprising one or more copolymers of tetrafluoroethylene on the layer comprisingfluorinated silanes bearing a fluorinated group such as to form a layer comprising a copolymer of tetrafluoroethylene.

    Abstract translation: 一种在衬底上形成热和化学惰性的多层膜的方法，包括在衬底上沉积包含一种或多种无机氧化物材料或其混合物的组合物，以形成包含至少部分熔融的无机 氧化物; 在包含熔融无机氧化物材料的连续层上沉积包含一种或多种非氟化硅烷化合物或其混合物的组合物，以形成包含非氟化聚硅氧烷的层; 在包含非氟化聚硅氧烷的层上沉积包含一种或多种氟化硅烷化合物的组合物，以形成含有氟化基团的含氟硅烷的层; 在包含氟化基团的氟化硅烷的层上沉积包含一种或多种四氟乙烯的共聚物的组合物，以形成包含四氟乙烯共聚物的层。

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