公开(公告)号：WO2017033176A1

公开(公告)日：2017-03-02

申请号：PCT/IL2016/050620

申请日：2016-06-14

Applicant: HYGIEACARE, INC.

Inventor： MERON, Gavriel David ,  FRISCH, Mordechai Yehuda

IPC: A61B7/04 ,  A61M3/02 ,  A61B10/02

CPC classification number: A61K35/37 ,  A61B5/42 ,  A61B5/6823 ,  A61B7/008 ,  A61B2505/05 ,  A61B2562/0204 ,  A61K9/0031 ,  A61K35/74 ,  A61K2035/11 ,  A61M1/0058 ,  A61M3/0204 ,  A61M2205/3375 ,  C12Q1/04

Abstract: Systems, kits and methods are provided, which analyze the large intestine content and utilize acoustic signals detected during delivery of water into the large intestine and drained large intestine contents to derive large intestine characteristics such as microbiotal analysis. Systems may include a water delivery unit including a water supply and a nozzle connected thereto, configured to introduce water controllably into a patient's large intestine, and an analysis unit that provides information about the drained contents using optical examination or biological assays. The information may be related to acoustic analysis of signals from acoustic sensors that are attachable to a patient's abdomen. A variety of sensor configurations, positioning options, analysis strategies and large intestine characteristics are presented.

Abstract translation: 提供了系统，试剂盒和方法，其分析大肠内容物，并利用在将大肠输送期间检测到的声信号和排出的大肠内容物，以获得大肠特征如微量分析。 系统可以包括水输送单元，其包括供水和连接到其上的喷嘴，其被配置为将水可控地引入患者的大肠中;以及分析单元，其使用光学检查或生物测定提供关于排出的内容的信息。 该信息可能与来自可附接到患者腹部的声学传感器的信号的声学分析有关。 介绍了各种传感器配置，定位选择，分析策略和大肠特征。

公开(公告)号：WO2023021339A1

公开(公告)日：2023-02-23

申请号：PCT/IB2022/055523

申请日：2022-06-15

Applicant: HYGIEACARE, INC.

Inventor： MERON, Gavriel David ,  LEVITAN, Orly ,  ARLINSKY, David Natan

IPC: C12Q1/04 ,  A61B1/12 ,  A61B5/00 ,  A61K35/37 ,  A61K35/74 ,  A61K9/00 ,  A61M3/02 ,  B25J15/00 ,  B25J9/06 ,  B25J9/10

Abstract: Sampling systems and methods for non-invasive analysis and sampling of inner-colonic microbiome and its potential derivatives are provided. Methods may relate portions of the drained contents to respective sections of the large intestine (including the ascending portion), during and/or after the draining and according to the time of drainage of the portions and optically-monitored (and possibly spectrally analyzed) characteristics of the drained content, and derive microbiome characteristics of the large intestine sections by analyzing the corresponding portions of the drained contents. An electromechanical sampling device may comprise a collection unit configured to collect s ample (s) from the contents, and an electromechanical robotic unit configured to move the collection unit to and from a sampling position and to manipulate the collection unit into a respective casing, to deposit the sample(s).