公开(公告)号：WO2021079328A1

公开(公告)日：2021-04-29

申请号：PCT/IB2020/059968

申请日：2020-10-23

Applicant: I.R.A. ISTITUTO RICERCHE APPLICATE S.P.A.

Inventor： CITERNESI, Ugo Raffaello ,  ANDOLINA, Gloria ,  FORMAGGIO, Fernando ,  PEGGION, Cristina ,  DI LIDDO, Rosa ,  PICCIONE, Monica ,  BERETTA, Lorenzo ,  CIVIDINI, Andrea ,  DE MARNI, Emanuele Giuseppe ,  CITERNESI, Lorenzo

IPC: C07K7/06 ,  C12N9/22 ,  A61K8/64 ,  A61K38/00

Abstract: The invention relates to selected peptides which repair, by means of nucleotide excision repair (NER), cellular DNA damaged by the exposure to external agents in particular UV rays and the cosmetic or pharmaceutical use thereof in skin treatment. The invention also relates to compositions for topical application containing the peptides preferably carried in liposomes to prevent and treat skin damage caused by the exposure to UV rays in particular in subjects affected by xeroderma pigmentosum.