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公开(公告)号:WO2017117386A8
公开(公告)日:2017-08-03
申请号:PCT/US2016069198
申请日:2016-12-29
Applicant: ICAHN SCHOOL MED MOUNT SINAI
Inventor: CAGAN ROSS , DAS TIRTHA KAMAL
IPC: A61K31/00 , A61K31/33 , A61K31/395 , A61P35/00 , C40B30/00
CPC classification number: A61K31/69 , A61K31/167 , A61K31/18 , A61K31/366 , A61K31/4045 , A61K31/436 , A61K31/437 , A61K31/44 , A61K31/4406 , A61K31/4545 , A61K31/4745 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5377 , A61K31/704 , A61K45/06 , G01N33/5011 , G01N33/5023 , G01N2333/91205 , G01N2440/14 , A61K2300/00
Abstract: The invention relates to improved methods of treating a cancer in a patient in need thereof using combination drug regimens that can improve therapeutic efficacy of kinase inhibitor(s). Such combination drug regimens may also reduce side effects of kinase inhibitor(s) and/or prevent or reduce cancer resistance to the kinase inhibitor(s).
Abstract translation: 本发明涉及使用可改善激酶抑制剂的治疗功效的组合药物疗法治疗有需要的患者的癌症的改进方法。 这种组合药物疗法还可以减少激酶抑制剂的副作用和/或预防或减少癌症对激酶抑制剂的抗性。