公开(公告)号：WO2023002505A1

公开(公告)日：2023-01-26

申请号：PCT/IN2022/050649

申请日：2022-07-19

申请人： INDIAN COUNCIL OF MEDICAL RESEARCH

发明人： NANDI, Shyam Sundar ,  LAMBE, Upendra ,  SAWANT, Sonali Ankush ,  DESHPANDE, Jagadish

IPC分类号： C12Q1/68 ,  C12Q1/70 ,  A61K39/215

摘要： The present invention relates to novel oligonucleotide sequences for rapid screening of epidemiologically important variants of SARS-CoV-2, wherein said oligonucleotide sequences acts as primers for amplification of sequences having Single-nucleotide polymorphisms (SNP)/mutations in the spike glycoprotein gene. The invention also relates to an assay for rapid screening of epidemiologically important variants of SARS-CoV-2 based upon using novel oligonucleotide sequences as primers. In particular, invention relates to oligonucleotide sequences of SEQ ID Nos. 1 – 37 for rapid screening of epidemiologically important variants of SARS-CoV-2.

公开(公告)号：WO2022208531A1

公开(公告)日：2022-10-06

申请号：PCT/IN2022/050276

申请日：2022-03-22

申请人： INDIAN COUNCIL OF MEDICAL RESEARCH

发明人： NANDI, Shyam Sundar ,  ROY, Subarna ,  LAMBE, Upendra ,  SAWANT, Sonali Ankush ,  GOHIL, Trupti ,  MURHEKAR, Manoj ,  DESHPANDE, Jagadish

IPC分类号： C12Q1/6844 ,  C12Q1/6876 ,  C12R1/16

摘要： The present invention relates to a novel primers and rapid loop mediated isothermal amplification method for detection of Corynebacterium diphtheriae. Further, the present invention also provides an assay for differentiating between toxigenic and non-toxigenic strains of C. diphtheriae.